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Secnidazole (trade names Flagentyl, Sindose, Secnil, Solosec) is a
nitroimidazole 5-Nitroimidazole is an organic compound with the formula O2NC3H2N2H. The nitro group at position 5 on the imidazole ring is the most common positional isomer. The term nitroimidazole also refers to a class of antibiotics that share similar chemi ...
anti-infective An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable d ...
. Effectiveness in the treatment of
dientamoebiasis Dientamoebiasis is a medical condition caused by infection with ''Dientamoeba fragilis'', a single-cell parasite that infects the lower gastrointestinal tract of humans. It is an important cause of traveler's diarrhea, chronic abdominal pain, chron ...
has been reported. It has also been tested against ''
Atopobium vaginae ''Fannyhessea vaginae'' is a species of bacteria in the family ''Atopobiaceae''. It is a facultative anaerobic, Gram-positive rod-shaped or elliptical coccobacilli found as single elements or in pairs or short chains. It is typically isolated fr ...
''. In the United States, secnidazole is FDA approved for the treatment of
bacterial vaginosis Bacterial vaginosis (BV) is a disease of the vagina caused by excessive growth of bacteria. Common symptoms include increased vaginal discharge that often smells like fish. The discharge is usually white or gray in color. Burning with urination ...
and
trichomoniasis Trichomoniasis (trich) is an infectious disease caused by the parasite ''Trichomonas vaginalis''. About 70% of affected people do not have symptoms when infected. When symptoms occur, they typically begin 5 to 28 days after exposure. Symptoms ca ...
in adult women.


References


Further reading

* Nitroimidazole antibiotics Antiprotozoal agents {{antiinfective-drug-stub