Scutavirus
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''Scutavirus'' is a genus of
viruses A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...
in the order ''
Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...
'', in the family ''
Herpesviridae ''Herpesviridae'' is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. The members of this family are also known as herpesviruses. The family name is derived from the Greek word ''ἕρπειν ...
'', in the subfamily ''
Alphaherpesvirinae ''Alphaherpesvirinae'' is a subfamily of viruses in the family ''Herpesviridae'', primarily distinguished by reproducing more quickly than other subfamilies in the ''Herpesviridae''. In animal virology the most important herpesviruses belong to ...
''. Turtles and tortoises serve as natural hosts. Diseases associated with this genus include fibropapillomatosis.


Species

The genus consists of the following two species: * ''
Chelonid alphaherpesvirus 5 Turtle fibropapillomatosis (FP) is a disease of sea turtles. The condition is characterized by benign but ultimately debilitating epithelial tumours on the surface of biological tissues. FP exists all over the world, but it is most prominent in ...
'' * ''
Testudinid alphaherpesvirus 3 ''Testudinid alphaherpesvirus 3'' (TeHV-3) is a species of virus in the genus ''Scutavirus'', subfamily ''Alphaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore g ...
''


Structure

Viruses in ''Scutavirus'' are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented.


Life cycle

Viral replication is nuclear, and is
lysogenic Lysogeny, or the lysogenic cycle, is one of two cycles of viral reproduction (the lytic cycle being the other). Lysogeny is characterized by integration of the bacteriophage nucleic acid into the host bacterium's genome or formation of a circul ...
. Entry into the host cell is achieved by attachment of the viral gB, gC, gD and gH proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Turtles and tortoises serve as the natural host.


References


External links


Viralzone: ''Scutavirus''

ICTV
{{Taxonbar, from=Q18813465 Alphaherpesvirinae Virus genera