Scott L. Pomeroy is the

Bronson Crothers Bronson Crothers (July 10, 1884 – July 17, 1959) was an American pediatric neurologist and a professor at Harvard Medical School. He studied birth trauma, cerebral palsy, and other neurological disabilities in children. Early life Bronson Crothe ...

Professor of Neurology and Director of the Intellectual and Developmental Disabilities Research Center of

Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...

, Chairman of the Department of Neurology and Neurologist-in-Chief of

Boston Children's Hospital Boston Children's Hospital formerly known as Children's Hospital Boston until 2012 is a nationally ranked, freestanding acute care children's hospital located in Boston, Massachusetts, adjacent both to its teaching affiliate, Harvard Medical Scho ...

, and an Associate Member of the

Broad Institute The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: , pronunciation respelling: ), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, Cambridge, Massachusetts, U ...

MIT The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the mo ...

and

Harvard Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...

Education

Pomeroy graduated from Wyoming High School in Ohio in 1971, received a B.A. in 1975 from

Miami University Miami University (informally Miami of Ohio or simply Miami) is a public research university in Oxford, Ohio. The university was founded in 1809, making it the second-oldest university in Ohio (behind Ohio University, founded in 1804) and the 10 ...

, M.D. / Ph.D. degrees in 1982 from the

University of Cincinnati College of Medicine The University of Cincinnati Academic Health Center (AHC) is a collection of health colleges and institutions of the University of Cincinnati, Cincinnati, Ohio. It trains health care professionals and provides research and patient care. AHC has st ...

and completed residencies in Pediatrics and Child Neurology respectively at

and

Washington University in St. Louis Washington University in St. Louis (WashU or WUSTL) is a private research university with its main campus in St. Louis County, and Clayton, Missouri. Founded in 1853, the university is named after George Washington. Washington University is r ...

and St. Louis Children's Hospital.

Research

His research was the first to apply genomic tools (such as

DNA microarrays A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to ...

) to understand the neurodevelopmental origins and molecular mechanisms of childhood brain tumors, especially

medulloblastoma Medulloblastoma is a common type of primary brain cancer in children. It originates in the part of the brain that is towards the back and the bottom, on the floor of the skull, in the cerebellum, or posterior fossa. The brain is divided into two ...

s, providing the basis for the current classification of these tumors.Confronting Cancer: Telling the Threatening Tumors from the Harmless Ones. NY Times April 9, 2002.Taylor MD, Northcott PA, Korshunov A, Remke M, Cho YJ, Clifford SC, Eberhart CG, Parsons W, Rutkowski S, Gajjar A, Ellison DW, Lichter P, Gilbertson RJ, Pomeroy SL, Kool M, Pfister SM. Molecular subgroups of medulloblastoma: The current consensus. ''Acta Neuropathol'' 2012; 123:456-472.Louis DN, et al. WHO Classification of Tumours of the Central Nervous System, 2016. This, in turn, led to targeted therapies for brain tumors based upon their more fundamental biology rather than their microscopic appearance. In addition, he has contributed to understanding the neurological outcomes of survivors of nervous system infections and cancer. He also serves as the child neurology editor of the textbook ''Neurology in Clinical Practice'' , one of the leading texts in the field, and of the nervous system volumes of the ''Netter Collection of Medical Illustrations''.Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL (eds). Bradley's Neurology in Clinical Practice (7th edition). Philadelphia: Elsevier 2016.

Awards

*Young Investigator Award, Child Neurology Society, 1989 *Compassionate Caregiver Award, Kenneth Schwartz Center, inaugural recipient 1999 *Sidney Carter Award, American Academy of Neurology, 2002 *Daniel Drake Medal, University of Cincinnati, 2007 *National Academy of Medicine, Elected Member 2017 *Bernard Sachs Award, Child Neurology Society, 2019

Selected publications

*Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, McLaughlin ME, Kim JYH, Goumnerova LC, Black PM, Lau C, Allen JC, Zagzag D, Olson JM, Curran T, Wetmore C, Biegel JA, Poggio T, Mukherjee S, Rifkin R, Califano A, Stolovitzky G, Louis DN, Mesirov JP, Lander ES and Golub TR. Prediction of central nervous system embryonal tumour outcome based on gene expression. ''Nature'' 2002; 415:436-442. *Cho YJ, Tsherniak A, Tamayo P, Greulich H, Lu J, Berhoukim R, Getz G, Amanil V, Goumnerova L, Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A, Haberler C, Delattre O, Kool M, Meyerson M, Mesirov JP, Pomeroy SL. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. ''J Clin Oncol'' 2011; 29:1424-1430. *Pugh TJ, Weeraratne SD, Archer TC, Pomeranz Krummel DA, Auclair D, Bochicchio J, Carneiro MO, Carter SL, Cibulskis K, Erlich RL, Greulich H, Lawrence MS, Lennon NJ, McKenna A, Meldrim J, Ramos AH, Ross MG, Russ C, Shefler E, Sivachenko A, Sogoloff B, Stanjanov P, Tamayo P, Mesirov JP, Amani V, Teider N, Sengupta S, Pierre Francois J, Northcott PA, Taylor MD, Yu F, Crabtree GR, Kautzman AG, Gabriel SB, Getz G, Jäger N, Jones DTW, Lichter P, Pfister SM, Roberts TM, Meyerson M*, Pomeroy SL*, Cho YJ*. Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. (*corresponding authors) ''Nature'' 2012; 488:106-110.

References

External links

*http://www.theschwartzcenter.org/supporting-caregivers/nccy-award/past-award-recipients/ *https://connects.catalyst.harvard.edu/Profiles/display/Person/41538 *https://med.uc.edu/about/drakemedal/ *https://nam.edu/national-academy-of-medicine-elects-80-new-members/ {{DEFAULTSORT:Pomeroy, Scott Miami University alumni University of Cincinnati College of Medicine alumni Harvard Medical School faculty Living people Year of birth missing (living people) Members of the National Academy of Medicine Washington University in St. Louis fellows Pediatric neurologists