Schrödinger, Inc. is an international scientific software company that specializes in developing computational tools and software for drug discovery and materials science.
Schrödinger's software is used by
pharmaceutical companies,
biotech
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
firms, and academic researchers to simulate and model the behavior of molecules at the atomic level. This accelerates the design and develops new drugs and materials more efficiently, reducing the time and cost of bringing them to market.
Schrödinger's software tools include molecular dynamics simulations, quantum mechanics calculations, and virtual screening tools. The company also offers consulting services and collaborates with partners in the industry to advance the field of computational chemistry and drug discovery.
Products and services
Schrödinger's computational platforms evaluate compounds in silico, with experimental accuracy on properties such as binding affinity and solubility. The company's products include molecular modeling programs, and an Enterprise Informatics Platform named LiveDesign, which is intended to facilitate communication among interdisciplinary research teams.
In addition to computational platforms, Schrödinger develops custom software for enterprises, as well as training, computer-cluster design and implementation, and research-based drug discovery projects.
Partners
Schrödinger's partners include pharmaceutical companies, including
Bayer
Bayer AG (, commonly pronounced ; ) is a German multinational corporation, multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of busi ...
,
Takeda, and more.
Nimbus Therapeutics, co-founded by Schrödinger, uses Schrödinger's drug screening and design platform for
drug discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by ...
. In 2016, Nimbus Therapeutics sold an
Acetyl-CoA carboxylase
Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme () that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT). ACC is ...
(ACC) inhibitor designed by Schrödinger to
Gilead Sciences in a deal worth up to $1.2 billion. As of spring 2019 the ACC inhibitor was moving through late-stage clinical trials in
non-alcoholic steatohepatitis.
Recognition
In November 2013, Schrödinger, in collaboration with
Cycle Computing
Cycle Computing is a company that provides software for orchestrating computing and storage resources in cloud environments. The flagship product is CycleCloud, which supports Amazon Web Services, Google Compute Engine, Microsoft Azure, and intern ...
and the
University of Southern California
The University of Southern California (USC, SC, or Southern Cal) is a Private university, private research university in Los Angeles, California, United States. Founded in 1880 by Robert M. Widney, it is the oldest private research university in C ...
, set a record for the world's largest and fastest cloud computing run by using 156,000 cores on
Amazon Web Services to screen over 205,000 molecules for materials science research. That work was a follow-up to a 2012 collaboration which saw Cycle Computing creating a 50,000 core virtual supercomputer using Amazon and Schrödinger's infrastructure, which at that time was used to analyze 2.1 million compounds in 3 hours.
References
External links
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American companies established in 1990
Software companies based in New York City
Molecular modelling software
Publicly traded companies based in New York City
Research support companies
Life sciences industry
Companies listed on the Nasdaq
2020 initial public offerings
Software companies of the United States
1990 establishments in the United States
1990 establishments in New York City
Software companies established in 1990