Schaumann Bodies
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In
pathology Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in ...
, Schaumann bodies are calcium and protein inclusions inside of
Langhans giant cell Langhans giant cells are large cells found in granulomatous conditions. They are formed by the fusion of epithelioid cells ( macrophages), and contain nuclei arranged in a horseshoe-shaped pattern in the cell periphery. Although traditionally ...
s as part of a granuloma. Many conditions can cause Schaumann bodies, including: *
Sarcoidosis Sarcoidosis (also known as ''Besnier-Boeck-Schaumann disease'') is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomata. The disease usually begins in the lungs, skin, or lymph nodes. Less commonly a ...
, *
Hypersensitivity pneumonitis Hypersensitivity pneumonitis (HP) or extrinsic allergic alveolitis (EAA) is a syndrome caused by the repetitive inhalation of antigens from the environment in susceptible or sensitized people. Common antigens include molds, bacteria, bird dropping ...
, and *
Berylliosis Berylliosis, or chronic beryllium disease (CBD), is a chronic allergic-type lung response and chronic lung disease caused by exposure to beryllium and its compounds, a form of beryllium poisoning. It is distinct from acute beryllium poisoning, wh ...
. *uncommonly, Crohn's disease and
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, i ...
.


Etymology

These inclusions were named after Swedish dermatologist Jörgen Nilsen Schaumann.


See also

*
Asteroid body An asteroid body is a microscopic finding seen within the giant cells of granulomas in diseases such as sarcoidosis and foreign-body giant cell reactions. There is controversy about their composition. Traditionally, they were thought to be cytos ...


References

Anatomical pathology {{pathology-stub