Salicylanilide is a chemical compound which is the
amide of
salicylic acid
Salicylic acid is an organic compound with the formula HOC6H4CO2H. A colorless, bitter-tasting solid, it is a precursor to and a metabolite of aspirin (acetylsalicylic acid). It is a plant hormone, and has been listed by the EPA Toxic Substance ...
and
aniline. It is classified as both a
salicylamide and an
anilide.
Derivatives of salicylanilide have a variety of pharmacological uses.
Chlorinated derivatives including
niclosamide,
oxyclozanide, and
rafoxanide are used as
anthelmintics, especially as
flukicides.
Brominated derivatives including
dibromsalan,
metabromsalan, and
tribromsalan are used as
disinfectant
A disinfectant is a chemical substance or compound used to inactivate or destroy microorganisms on inert surfaces. Disinfection does not necessarily kill all microorganisms, especially resistant bacterial spores; it is less effective than st ...
s with
antibacterial and
antifungal
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as crypto ...
activities.
File:Bromochlorosalicylanilide.svg , Bromochlorosalicylanilide
File:Niclosamide.svg , Niclosamide
File:Oxyclozanide.svg , Oxyclozanide
File:Rafoxanide.svg , Rafoxanide
Uses
Salicylanilides may be used as
antiseptics.
References
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