SR 59230A is a selective antagonist of the

beta-3 adrenergic receptor The beta-3 adrenergic receptor (β3-adrenoceptor), also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it. Function Actions of the β3 receptor include *Enhancement of lipolysis in adipose tissue. *Ther ...

, but was subsequently shown to also act at α₁ adrenoceptors at high doses. It has been shown to block the

hyperthermia Hyperthermia, also known simply as overheating, is a condition in which an individual's body temperature is elevated beyond normal due to failed thermoregulation. The person's body produces or absorbs more heat than it dissipates. When extreme ...

produced by

MDMA 3,4-Methylenedioxymethamphetamine (MDMA), commonly seen in Tablet (pharmacy), tablet form (ecstasy) and crystal form (molly or mandy), is a potent empathogen–entactogen with stimulant properties primarily used for Recreational dru ...

in animal studies.

References

Beta blockers Phenol ethers Secondary alcohols 1-Aminotetralins {{Alcohol-stub