Sodium-dependent phosphate transport protein 2B (NaPi2b) is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''SLC34A2''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Clinical significance
Sodium-dependent phosphate transport protein 2b (NaPi2b) is a
tumor-associated antigen
Tumor antigen is an antigenic substance produced in tumor Cell (biology), cells, i.e., it triggers an immune response in the Host (biology), host. Tumor antigens are useful tumor markers in identifying tumor cells with diagnostic tests and are po ...
.
See also
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Solute carrier family
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Pulmonary alveolar microlithiasis
Pulmonary alveolar microlithiasis (PAM) is a rare, inherited disorder of lung phosphate balance that is associated with small stone formation in the airspaces of the lung. Mutations in the gene '' SLC34A2'' result in loss of a key sodium, phospha ...
References
Further reading
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Solute carrier family
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