Neuronal-specific septin-3 is a

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...

that in humans is encoded by the ''SEPT3''

gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...

Function

This gene belongs to the

septin Septins are a group of guanosine triphosphate, GTP-molecular binding, binding proteins gene expression, expressed in all eukaryote, eukaryotic cells except plants. Different septins form protein complexes with each other. These complexes can furt ...

family of GTPases. Members of this family are required for

cytokinesis Cytokinesis () is the part of the cell division process during which the cytoplasm of a single eukaryotic cell divides into two daughter cells. Cytoplasmic division begins during or after the late stages of nuclear division in mitosis and meios ...

. Expression is upregulated by retinoic acid in a human

teratocarcinoma Germ cell tumor (GCT) is a neoplasm derived from germ cells. Germ-cell tumors can be cancerous or benign. Germ cells normally occur inside the gonads (ovary and testis). GCTs that originate outside the gonads may be birth defects resulting from er ...

cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in multiple transcript variants.

Function

References

Further reading