(''S'')-SCQ1 is a drug which acts as a potent and selective

antagonist An antagonist is a character in a story who is presented as the chief foe of the protagonist. Etymology The English word antagonist comes from the Greek ἀνταγωνιστής – ''antagonistēs'', "opponent, competitor, villain, enemy, riv ...

for the 5-HT_2B and 5-HT_2C

serotonin Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vas ...

receptors, but with only modest affinity for the closely related 5-HT_2A receptor and other targets such as 5-HT₇. Since most currently available 5-HT₂ class ligands have relatively poor selectivity and bind to all three subtypes, the selectivity of (''S'')-SCQ1 is expected to be useful for studying 5-HT_2A receptor mediated responses in the absence of 5-HT_2B and 5-HT_2C activation.

References

{{Serotonergics 5-HT2C antagonists Benzochromenes Ketones Spiro compounds Nitrogen heterocycles

See also

References