SADI-S
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SADI-S (Single anastomosis duodeno–ileal bypass with
sleeve gastrectomy Sleeve gastrectomy is a surgical weight-loss procedure in which the stomach is reduced to about 15% of its original size, by surgical removal of a large portion of the stomach along the greater curvature. The result is a sleeve or tube like struc ...
) is a bariatric surgical technique to address metabolic disorders and to lose weight. It is a variation on the Duodenal Switch surgery, incorporating a vertical sleeve gastrectomy with a
gastric bypass Gastric bypass surgery refers to a technique in which the stomach is divided into a small upper pouch and a much larger lower "remnant" pouch and then the small intestine is rearranged to connect to both. Surgeons have developed several differ ...
technique. The SADI-S is a type of bariatric surgery with a single surgical anastomosis. It has a restrictive component when reducing the greater curvature of the stomach, but especially a malabsorptive component, as the common channel is also reduced. The objective of this surgical technique is to lessen the intestinal loop where nutrients are absorbed.


Technique

It can be performed by
laparotomy A laparotomy is a surgical procedure involving a surgical incision through the abdominal wall to gain access into the abdominal cavity. It is also known as a celiotomy. Origins and history The first successful laparotomy was performed without ane ...
or
laparoscopy Laparoscopy () is an operation performed in the abdomen or pelvis using small incisions (usually 0.5–1.5 cm) with the aid of a camera. The laparoscope aids diagnosis or therapeutic interventions with a few small cuts in the abdomen.Medlin ...
. A small gastric sleeve is created by sectioning the greater curvature of the stomach, such as in the sleeve technique. Subsequently, the duodenum is transected respecting the pylorus. A duodenum-intestinal anastomosis is carried out between and from the ileocecal valve. Therefore, this distance becomes the length of the common channel where nutrients are absorbed.


Advantages

The SADI-S is a single anastomosis bariatric surgery. It is different from the classic duodenal switch, the gastric bypass (RNY) or
sleeve gastrectomy Sleeve gastrectomy is a surgical weight-loss procedure in which the stomach is reduced to about 15% of its original size, by surgical removal of a large portion of the stomach along the greater curvature. The result is a sleeve or tube like struc ...
. It is a type of bariatric surgery carried out to lose weight and to mitigate various metabolic issues including
Type 2 Diabetes Type 2 diabetes, formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urinatio ...
, dislipidemia, Metabolic Syndrome, and
Polycystic Ovarian Syndrome Polycystic ovary syndrome, or PCOS, is the most common endocrine disorder in women of reproductive age. The syndrome is named after the characteristic cysts which may form on the ovaries, though it is important to note that this is a sign and no ...
. In published studies, total weight loss and the positive impact or remission of Type 2 Diabetes was better with the SADI-S surgery than with gastric bypass or sleeve gastrectomy. When compared to RNY surgery, the SADI preserves the stomach/pyloric valve, thus maintaining more anatomical control over release of food into the intestines, and reducing the risk or frequency of dumping syndrome. When compared to the Duodenal Switch (DS), in addition to requiring only a single anastomosis (which reduces the incidence of leakage or stricture complication ), the SADI surgery typically leaves a longer common channel than the DS. This reduces the severity of malnutrition tied to malabsorption, and mitigates the degree of diarrhea and flatulence associated with DS.


Disadvantages

As with other bariatric malabsorptive techniques, including RNY and DS, patients will need to take vitamin supplements A, D, E, K and minerals throughout their lives. Analytical monitoring is necessary to prevent malnutrition. Stones in the gallbladder, flatulence and diarrhea are more frequent than with the non-bariatric population. The surgical risks are similar as in other bariatric techniques, including intestinal perforation, infection, abscess, venous thrombosis, pulmonary embolism, and andanastomotic leaks (although the single anastomosis is designed to present less risk overall compared to the multi-anastomosis techniques). In the long term, it can produce a bowel obstruction. There is a greater chance of bile reflux than a traditional duodenal switch. While previously considered experimental, in 2020 and 2018, respectively, both the
American Society of Metabolic and Bariatric Surgery
(ASMBS) an
The International Federation for Surgery of Obesity and Metabolic Disorders
(IFSO) released statements endorsing SADI as an effective and established surgical technique.''Single Anastomosis Duodenal-Ileal Bypass with Sleeve Gastrectomy/One Anastomosis Duodenal Switch (SADI-S/OADS) IFSO Position Statement-Update 2020'' Obesity Surgery 30, p3 (2021). While there is no research to indicate that it has any significant reduction in vitamin or mineral supplementation as compared to the Roux-en-Y gastric bypass surgical technique, the typically longer common channel in SADI, compared to Duodenal Switch surgery, means there is a somewhat lower degree of nutritional deficiency.


See also

*
SIPS surgery Stomach Intestinal Pylorus-Sparing (SIPS) surgery is a type of weight-loss surgery. It was developed in 2013 by two U.S. surgeons, Daniel Cottam from Utah and Mitchell S. Roslin from New York. It is substantively the same procedure as the SADI s ...


Bibliography

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External links

* {{Commonscatinline
Single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S). One to three-year follow-up.
Surgical procedures and techniques Bariatric surgery