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Ruth Frances Bishop (12 May 1933 – 12 May 2022)''Who's Who in Australia'', ConnectWeb, 2013. was an Australian
virologist Virology is the scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host cells for reproduction, th ...
, who was a leading member of the team that discovered the human
rotavirus ''Rotavirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae''. Rotaviruses are the most common cause of diarrhoeal disease among infants and young children. Nearly every child in the world is infected with a rotavirus ...
.


Biography

Bishop was born in Dandenong, Victoria, and grew up in Frankston where her father was principal of Frankston High School.Precel, Nicole (30 October 2013).
Professor Ruth Bishop wins 2013 CSL Florey Medal
. '' Frankston Standard Leader''.
News Limited News Corp Australia is an Australian media conglomerate and wholly owned subsidiary of the American News Corp. One of Australia's largest media conglomerates, News Corp Australia employs more than 8,000 staff nationwide and approximately 3,000 ...
. Retrieved 17 October 2015
Bishop graduated with a
PhD PHD or PhD may refer to: * Doctor of Philosophy (PhD), an academic qualification Entertainment * '' PhD: Phantasy Degree'', a Korean comic series * '' Piled Higher and Deeper'', a web comic * Ph.D. (band), a 1980s British group ** Ph.D. (Ph.D. a ...
in
microbiology Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, ...
in 1961. In 1973, Bishop, along with Geoffrey Davidson ( Royal Children's Hospital) and collaborators Ian Holmes and Brian Ruck (
University of Melbourne The University of Melbourne is a public research university located in Melbourne, Australia. Founded in 1853, it is Australia's second oldest university and the oldest in Victoria. Its main campus is located in Parkville, an inner suburb no ...
), examined cells from the intestines of children with
gastroenteritis Gastroenteritis, also known as infectious diarrhea and gastro, is an inflammation of the gastrointestinal tract including the stomach and intestine. Symptoms may include diarrhea, vomiting, and abdominal pain. Fever, lack of energy, and dehydrat ...
. Intestinal biopsies were taken at the Royal Children's Hospital in Melbourne, Australia, and sent to Ian Holmes and Brian Ruck (University of Melbourne) to be examined by electron-microscopy. Under the
electron microscope An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a ...
cells were seen to be infected with viruses, which were originally named "duovirus" because they were seen in the duodenum and had a double
capsid A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or m ...
. The name "rotavirus" was later suggested by the Irishman, Thomas Henry Flewett, because of the round, wheel-like shape of virus particles. Rotaviruses cause diarrhoea and vomiting in young children and are a leading cause of death in the developing countries. Three thousand children are now hospitalised with rotavirus every year, down from 10,000 before the vaccine was introduced in 2007. Bishop said the invention of electron microscopy helped her make the discovery. The team's discovery led to a global effort to control of rotavirus. Bishop also published theoretical works about the patterns in the epidemiology of rotavirus infection. From 1983 to 1988, Bishop was Chair of the Committee on Diarrhoeal Diseases with the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of ...
(WHO).


Awards and honours

Bishop was made an
Officer of the Order of Australia The Order of Australia is an honour that recognises Australian citizens and other persons for outstanding achievement and service. It was established on 14 February 1975 by Elizabeth II, Queen of Australia, on the advice of the Australian Gov ...
(AO) in the 1996 Queen's Birthday Honours in recognition of service to medical research, particularly for her contributions to the understanding of gastroenteritis in children.BISHOP, Ruth Frances AO
''It's an Honour'', 11 June 1996.
In the 2019 Queen's Birthday Honours she was promoted to
Companion of the Order of Australia The Order of Australia is an honour that recognises Australian citizens and other persons for outstanding achievement and service. It was established on 14 February 1975 by Elizabeth II, Queen of Australia, on the advice of the Australian Gov ...
(AC) for "eminent service to global child health through the development of improved vaccines for paediatric gastroenteritis, and to medical research". In 2001, she was inducted to the Victorian Honour Roll of Women. In 2011, she received the Prince Mahidol Award awarded by the Thai Royal Family for outstanding achievement in public health. Bishop was awarded the Florey Medal in 2013 for her discovery of rotavirus and subsequent work helping to develop a vaccine. The medal recognises significant achievements in biomedical research.ABC News Online (28 Oct 2013) "Professor Ruth Bishop awarded Florey Medal for work on rotavirus vaccine.

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References

{{DEFAULTSORT:Bishop, Ruth 1933 births 2022 deaths Australian virologists Australian women scientists Officers of the Order of Australia Companions of the Order of Australia World Health Organization officials University of Melbourne alumni University of Melbourne faculty University of Melbourne women Australian officials of the United Nations