Ronald Keith Siegel (January 2, 1943 – March 24, 2019) was an American psychopharmacologist who was an associate research professor in the Department of Psychiatry and Biobehavioral Sciences at the

University of California, Los Angeles The University of California, Los Angeles (UCLA) is a public land-grant research university in Los Angeles, California. UCLA's academic roots were established in 1881 as a teachers college then known as the southern branch of the California ...

. Siegel was the author of several noted studies and books on

psychopharmacology Psychopharmacology (from Greek grc, ψῡχή, psȳkhē, breath, life, soul, label=none; grc, φάρμακον, pharmakon, drug, label=none; and grc, -λογία, -logia, label=none) is the scientific study of the effects drugs have on mo ...

hallucination A hallucination is a perception in the absence of an external stimulus that has the qualities of a real perception. Hallucinations are vivid, substantial, and are perceived to be located in external objective space. Hallucination is a combinati ...

, and

paranoia Paranoia is an instinct or thought process that is believed to be heavily influenced by anxiety or fear, often to the point of delusion and irrationality. Paranoid thinking typically includes persecutory beliefs, or beliefs of conspiracy co ...

. A native of

Herkimer, New York Herkimer is a town in Herkimer County, New York, United States, southeast of Utica. It is named after Nicholas Herkimer. The population was 10,175 at the 2010 census. The town contains a village also called Herkimer. Herkimer County Community ...

, he received his

B.A. Bachelor of arts (BA or AB; from the Latin ', ', or ') is a bachelor's degree awarded for an undergraduate program in the arts, or, in some cases, other disciplines. A Bachelor of Arts degree course is generally completed in three or four years ...

sociology Sociology is a social science that focuses on society, human social behavior, patterns of social relationships, social interaction, and aspects of culture associated with everyday life. It uses various methods of empirical investigation and ...

from

Brandeis University , mottoeng = "Truth even unto its innermost parts" , established = , type = Private research university , accreditation = NECHE , president = Ronald D. Liebowitz , pr ...

and his

Ph.D. A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is ...

psychology Psychology is the scientific study of mind and behavior. Psychology includes the study of conscious and unconscious phenomena, including feelings and thoughts. It is an academic discipline of immense scope, crossing the boundaries between ...

from

Dalhousie University Dalhousie University (commonly known as Dal) is a large public research university in Nova Scotia, Canada, with three campuses in Halifax, a fourth in Bible Hill, and a second medical school campus in Saint John, New Brunswick. Dalhousie offe ...

. He was affiliated with the Albert Einstein College of Medicine at

Yeshiva University Yeshiva University is a private Orthodox Jewish university with four campuses in New York City."About YU
on the Yeshiva Universi ...

before joining the research faculty of UCLA in 1972, where he remained until his retirement in 2008. Throughout his career, he was a consultant to several government commissions on drug use. His research focused on the effects of drugs on human behavior, including numerous clinical studies in which human volunteers (sometimes referred to by Siegel as " psychonauts") took drugs such as

ketamine Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a recreational drug. It is one of the safest anesthetics, as, in contrast with opiates, ether, and propofol, it suppresses ...

LSD Lysergic acid diethylamide (LSD), also known colloquially as acid, is a potent psychedelic drug. Effects typically include intensified thoughts, emotions, and sensory perception. At sufficiently high dosages LSD manifests primarily mental, vi ...

marijuana Cannabis, also known as marijuana among other names, is a psychoactive drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various tra ...

mescaline Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. Biological sour ...

psilocybin Psilocybin ( , ) is a naturally occurring psychedelic prodrug compound produced by more than 200 species of fungi. The most potent are members of the genus ''Psilocybe'', such as '' P. azurescens'', '' P. semilanceata'', and '' P.&nbs ...

, and

THC Tetrahydrocannabinol (THC) is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C21H30O2) describes multiple isomers, the term ''THC'' ...

. In 2005, Siegel was an expert witness for the defense in the

Robert Blake Robert Blake may refer to: Sportspeople * Bob Blake (American football) (1885–1962), American football player * Robbie Blake (born 1976), English footballer * Bob Blake (ice hockey) (1914–2008), American ice hockey player * Rob Blake (born ...

murder trial, testifying on the long-term effects of

methamphetamine Methamphetamine (contracted from ) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. Methamph ...

and cocaine use. According to the jury foreman in the trial, Siegel was "one of the most compelling witnesses" in discrediting the testimony of Ronald Hambleton, who claimed that Blake had asked him to murder Bonnie Lee Bakley. In the course of his testimony in the Blake trial, Siegel disclosed that in one study, he had taught monkeys to smoke crack cocaine. He died on March 24, 2019 from complications of

Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As ...

Bibliography

* (with Jolly West) *''Intoxication: The Universal Drive for Mind-Altering Substances'' (1989, 2005) * *'' Whispers: The Voices of Paranoia'' (1994) * * *

Notes

{{DEFAULTSORT:Siegel, Ronald K American pharmacologists Psychopharmacologists Psychedelic drug researchers American medical writers American male non-fiction writers Harvard Medical School people David Geffen School of Medicine at UCLA faculty Albert Einstein College of Medicine alumni 1943 births 2019 deaths