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Rick Strassman is an American clinical associate professor of psychiatry at the
University of New Mexico School of Medicine The University of New Mexico School of Medicine (UNM School of Medicine) is a division of the University of New Mexico Health Sciences Center (UNM HSC) located in Albuquerque, New Mexico. The UNM School of Medicine is home to a variety of degree-g ...
. He has held a fellowship in clinical psychopharmacology research at the University of California San Diego and was Professor of Psychiatry for eleven years at the University of New Mexico. After 20 years of intermission, Strassman was the first person in the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territori ...
to undertake human research with psychedelic,
hallucinogenic Hallucinogens are a large, diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes. Most hallucinogens can be categorized ...
, or
entheogenic Entheogens are psychoactive substances that induce alterations in perception, mood, consciousness, cognition, or behavior for the purposes of engendering spiritual development or otherwiseRätsch, Christian, ''The Encyclopedia of Psychoact ...
substances with his research on ''N,N''-dimethyltryptamine, also known as DMT. He is also the author of '' DMT: The Spirit Molecule'', which summarizes his academic research into DMT and other experimental studies of it, and includes his own reflections and conclusions based on this research.


Life and education

Strassman was born in Los Angeles, California, on February 8, 1952. He graduated from Ulysses S. Grant High School in Van Nuys in 1969. He studied zoology at
Pomona College Pomona College ( ) is a private liberal arts college in Claremont, California. It was established in 1887 by a group of Congregationalists who wanted to recreate a "college of the New England type" in Southern California. In 1925, it became t ...
in Claremont for two years before transferring to Stanford University, where he graduated with departmental honors in biological sciences in 1973. He continued laboratory research at Stanford before attending
Albert Einstein College of Medicine Albert Einstein College of Medicine is a research-intensive medical school located in the Morris Park neighborhood of the Bronx in New York City. Founded in 1953, Einstein operates as an independent degree-granting institution as part of t ...
of
Yeshiva University Yeshiva University is a private Orthodox Jewish university with four campuses in New York City."About YU
on the Yeshiva Universi ...
in New York, where he graduated with an
M.D. Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. ...
with departmental honors, specializing in psychiatry. He began his general psychiatry residency at the
University of California, Davis The University of California, Davis (UC Davis, UCD, or Davis) is a public land-grant research university near Davis, California. Named a Public Ivy, it is the northernmost of the ten campuses of the University of California system. The inst ...
, where he received the Sandoz Award for outstanding graduating resident in 1981. From 1982 to 1983, he trained as a fellow in clinical psychopharmacology research at the
University of California, San Diego The University of California, San Diego (UC San Diego or colloquially, UCSD) is a public land-grant research university in San Diego, California. Established in 1960 near the pre-existing Scripps Institution of Oceanography, UC San Diego is t ...
. He then served on the clinical faculty in the psychiatry department at UC Davis Medical Center, before becoming an assistant professor in the psychiatry department at the University of New Mexico School of Medicine in Albuquerque in 1984. At UNM, Strassman researched the function of the pineal gland. His research group documented the first known role of melatonin in humans. He became clinical associate professor of psychiatry in 1991. He has published over 40 peer-reviewed scientific articles on
psychopharmacology Psychopharmacology (from Greek grc, ψῡχή, psȳkhē, breath, life, soul, label=none; grc, φάρμακον, pharmakon, drug, label=none; and grc, -λογία, -logia, label=none) is the scientific study of the effects drugs have on mo ...
,
neurology Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal ...
,
psychiatry Psychiatry is the specialty (medicine), medical specialty devoted to the diagnosis, prevention, and treatment of mental disorders. These include various maladaptations related to mood, behaviour, cognition, and perceptions. See glossary of psych ...
,
neuroendocrinology Neuroendocrinology is the branch of biology (specifically of physiology) which studies the interaction between the nervous system and the endocrine system; i.e. how the brain regulates the hormonal activity in the body. The nervous and endocrine ...
and
neuropsychopharmacology Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (study of effects of drugs on the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails ...
.


Developmental biology research

As an undergraduate at Stanford, working in the developmental biology laboratory of Norman K. Wessells, Strassman developed a new model for growing embryonic avian dorsal root ganglion neurons, suspended in a semi-solid agar matrix, thus allowing three-dimensional assessment of growing patterns. Using this model, he discovered a nonrandom pattern of growth of the leading edge of these cells.


Melatonin research

Strassman's interest in the human biology of altered states of consciousness led him to study the pineal gland
hormone A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and behavior. Hormones are require ...
melatonin in the 1980s, at which time there were suggestive data regarding its psychoactive effects. This research took place at the University of New Mexico's School of Medicine in Albuquerque, where he became a tenured associate professor of psychiatry. He first developed a model of all-night suppression of melatonin by all-night bright light. He then established a successful exogenous melatonin infusion protocol that replicated endogenous melatonin levels in the bright-light conditions. All-night bright-light suppression of melatonin suppressed the normal trough of body temperature seen between 3-4 a.m., the time of maximum melatonin levels. Exogenous infusion of melatonin, replicating endogenous levels in the bright-light condition (in which endogenous melatonin was suppressed) reestablished the normal core body temperature trough. But melatonin's psychoactive effects were only sedative, leading him to focus on DMT in his future work.


Research into DMT

From 1990 to 1995, Strassman led a government-funded clinical research team at the University of New Mexico studying the effects of ''N,N''-dimethyltryptamine, also known as DMT, on human subjects in experimental conditions. The research continued from his work on melatonin. Strassman's studies between 1990 and 1995 aimed to experimentally investigate DMT's effects. DMT is a powerful psychedelic drug found in hundreds of plants and every mammal that has been studied. It is made primarily in mammalian lung tissue and is related to serotonin and melatonin. As a result of his research, Strassman came to call DMT the "spirit molecule" because its effects include many features of
religious experience A religious experience (sometimes known as a spiritual experience, sacred experience, or mystical experience) is a subjective experience which is interpreted within a religious framework. The concept originated in the 19th century, as a defense ...
, such as visions, voices, disembodied consciousness, powerful emotions, novel insights, and feelings of overwhelming significance. During the project's five years, he administered approximately 400 doses of DMT to nearly 60 human volunteers. Strassman was the first in 20 years to legally administer psychedelics to people in the United States, and his research has widely been regarded as kicking off the "psychedelic renaissance", in which many psychedelic compounds have begun to be scientifically studied for the first time since the early 1970s. Strassman characterized DMT's biological and psychological effects in his first set of dose-response studies, effects consistent with activation of central and/or peripheral serotonin receptors. His team published a companion article describing the psychological effects and preliminary results of a new rating scale, the Hallucinogen Rating Scale, or HRS. Researchers have widely accepted the HRS as a sensitive and specific measure of the psychological effects of a wide variety of psychoactive substances, with over 45 articles documenting its use as of mid-2015. A follow-up study demonstrated lack of tolerance of the psychological effects of repeated closely spaced doses of DMT, making it unique among classical psychedelics. More than half of Strassman's volunteers reported profound encounters/interaction with nonhuman beings while in a dissociated state. Strassman has conjectured that when a person is approaching death or possibly when in a dream state, the body releases a relatively large amount of DMT, mediating some of the imagery survivors of near-death experiences report. But there are no data correlating endogenous DMT activity to non-drug-related altered states of consciousness. He also has theorized that the pineal gland may form DMT under certain conditions. In 2013 researchers first reported DMT in the pineal gland microdialysate of rodents. Strassman has detailed his research in his book ''DMT: The Spirit Molecule'', and co-produced a 2010 documentary film of the same name based on this book. He has also conducted similar research on psilocybin, a psychedelic alkaloid found in hallucinogenic mushrooms. In unpublished studies, he administered doses of up to 1.1 mg/kg, nearly three times the doses considered "psychedelic" in contemporary clinical research with this compound.


Religious models for integrating DMT experiences

Inspired by visions he had when he took
LSD Lysergic acid diethylamide (LSD), also known colloquially as acid, is a potent psychedelic drug. Effects typically include intensified thoughts, emotions, and sensory perception. At sufficiently high dosages LSD manifests primarily mental, vi ...
in the early 1970s, Strassman began studying Buddhism as a young man. He trained for 20 years in
Zen Buddhism Zen ( zh, t=禪, p=Chán; ja, text= 禅, translit=zen; ko, text=선, translit=Seon; vi, text=Thiền) is a school of Mahayana Buddhism that originated in China during the Tang dynasty, known as the Chan School (''Chánzong'' 禪宗), an ...
, received lay ordination in a Western Buddhist order, and led a meditation group of the order. But his work with DMT led him to feel Buddhist models may not be the most suitable way for us to explain and integrate the spiritual dimensions of the DMT experience: Strassman suggests that DMT experiences may most closely resemble those found in the Hebrew Bible's model of prophecy: Some of Strassman's experimental participants say that other entities can resemble creatures more like insects and aliens than anything in the Bible.Strassman (2001): 206-208. As a result, Strassman wrote that these experiences of his experimental participants "also left me feeling confused and concerned about where the spirit molecule was leading us. It was at this point that I began to wonder if I was getting in over my head with this research."Strassman (2001): 202. He has also hypothesized that endogenous DMT experiences could be the cause of
alien abduction Alien abduction (also called abduction phenomenon, alien abduction syndrome, or UFO abduction) refers to the phenomenon of people reporting their experience of being kidnapped by extraterrestrial beings and subjected to physical and psychologica ...
experiences.


See also

* Luis Eduardo Luna *
Terence McKenna Terence Kemp McKenna (November 16, 1946 – April 3, 2000) was an American ethnobotanist and mystic who advocated the responsible use of naturally occurring psychedelic plants. He spoke and wrote about a variety of subjects, including ...
*
Dennis McKenna Dennis Jon McKenna (born December 17, 1950 in Paonia, Colorado) is an American ethnopharmacologist, research pharmacognosist, lecturer and author. He is the brother of well-known psychedelics proponent Terence McKenna and is a founding board ...
* Jeremy Narby * David E. Nichols *
Jonathan Ott Jonathan Ott (born 1949 in Hartford, Connecticut) is an ethnobotanist, writer, translator, publisher, natural products chemist and botanical researcher in the area of entheogens and their cultural and historical uses, and helped coin the term "' ...
*
Benny Shanon Benny Shanon ( he, בני שנון; born 1948) is an emeriti professor of psychology at the Hebrew University of Jerusalem and holds the Mandel Chair in cognitive psychology and education. Born in Tel Aviv, Shanon studied philosophy and linguistics ...
* '' DMT: The Spirit Molecule'', a documentary based on Strassman's nonfiction book of the same name


Bibliography

*''DMT: The Spirit Molecule: A Doctor's Revolutionary Research into the Biology of Near-Death and Mystical Experiences'', 320 pages
Park Street Press
2001, *''Inner Paths to Outer Space: Journeys to Alien Worlds through Psychedelics and Other Spiritual Technologies'', 376 pages, with Slawek Wojtowicz, Luis Eduardo Luna and Ede Frecska
Park Street Press
2008, *''DMT and the Soul of Prophecy: A New Science of Spiritual Revelation in the Hebrew Bible'', 352 pages
Park Street Press
2014, *''Joseph Levy Escapes Death'', Regents Press Printers & Publishers, 2019


References


External links


Official homepageCottonwood Research FoundationRick Strassman's YouTube Channel
{{DEFAULTSORT:Strassman, Rick Psychedelic drug researchers Living people People from Los Angeles 1952 births Pomona College alumni