Rugulovasines are bio-active

alkaloids Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar st ...

made by ''Penicillium''. Rugulovasine A and B bind strongly to the 5-HT_1A, 5-HT_2A, and 5-HT_2C receptors, but lack meaningful binding affinity towards the α₁ adrenergic and

dopamine receptors Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through diffe ...

. Little is known about the ''in vivo'' activity of Rugulovasine A and B, although they have hypotensive effects in cats.

References

Tryptamine alkaloids {{Alkaloid-stub Rugulovasine