Ruggero Oddi (July 20, 1864 – March 22, 1913) was an Italian

physiologist Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical a ...

and

anatomist Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its ...

who was a native of

Perugia Perugia (, , ; lat, Perusia) is the capital city of Umbria in central Italy, crossed by the River Tiber, and of the province of Perugia. The city is located about north of Rome and southeast of Florence. It covers a high hilltop and part o ...

. He is most well known for the

Sphincter of Oddi The sphincter of Oddi (also hepatopancreatic sphincter or Glisson's sphincter), abbreviated as SO, is a muscular valve that in some animals, including humans, controls the flow of digestive juices (bile and pancreatic juice) out of the pancreas t ...

, which was named after him.

Biography

He studied medicine at Perugia,

University of Bologna The University of Bologna ( it, Alma Mater Studiorum – Università di Bologna, UNIBO) is a public research university in Bologna, Italy. Founded in 1088 by an organised guild of students (''studiorum''), it is the oldest university in continuo ...

Ruggero Oddi
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Florence Florence ( ; it, Firenze ) is a city in Central Italy and the capital city of the Tuscany region. It is the most populated city in Tuscany, with 383,083 inhabitants in 2016, and over 1,520,000 in its metropolitan area.Bilancio demografico an ...

, and in 1894 was appointed head of the Physiology Institute at the

University of Genoa The University of Genoa, known also with the acronym UniGe ( it, Università di Genova), is one of the largest universities in Italy. It is located in the city of Genoa and regional Metropolitan City of Genoa, on the Italian Riviera in the Liguri ...

. In 1900 he was relieved of his position at Genoa because of

narcotic The term narcotic (, from ancient Greek ναρκῶ ''narkō'', "to make numb") originally referred medically to any psychoactive compound with numbing or paralyzing properties. In the United States, it has since become associated with opiates ...

s usage and fiscal improprieties. Later, he sought employment as a doctor with the

Belgian Belgian may refer to: * Something of, or related to, Belgium * Belgians, people from Belgium or of Belgian descent * Languages of Belgium, languages spoken in Belgium, such as Dutch, French, and German *Ancient Belgian language, an extinct languag ...

colonial medical service, and spent some time working in the

Belgian Congo The Belgian Congo (french: Congo belge, ; nl, Belgisch-Congo) was a Belgian colony in Central Africa from 1908 until independence in 1960. The former colony adopted its present name, the Democratic Republic of the Congo (DRC), in 1964. Colo ...

. Oddi died on March 22, 1913 in

Tunis ''Tounsi'' french: Tunisois , population_note = , population_urban = , population_metro = 2658816 , population_density_km2 = , timezone1 = CET , utc_offset1 ...

Tunisia ) , image_map = Tunisia location (orthographic projection).svg , map_caption = Location of Tunisia in northern Africa , image_map2 = , capital = Tunis , largest_city = capital , ...

. While still a student, in 1887, 23-year-old Oddi described a small group of circular and longitudinal muscle fibers that wrapped around the end of the

bile Bile (from Latin ''bilis''), or gall, is a dark-green-to-yellowish-brown fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine. In humans, bile is produced continuously by the liver (liver bile ...

and

pancreatic The pancreas is an Organ (anatomy), organ of the digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity, abdomen behind the stomach and functions as a gland. The pancreas is a mixed or heterocrine ...

ducts in 1887. This structure was later to be known as the

eponymous An eponym is a person, a place, or a thing after whom or which someone or something is, or is believed to be, named. The adjectives which are derived from the word eponym include ''eponymous'' and ''eponymic''. Usage of the word The term ''epon ...

sphincter of Oddi The sphincter of Oddi (also hepatopancreatic sphincter or Glisson's sphincter), abbreviated as SO, is a muscular valve that in some animals, including humans, controls the flow of digestive juices (bile and pancreatic juice) out of the pancreas t ...

". Oddi was not the original discoverer of the

sphincter A sphincter is a circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. Sphincters are found in many animals. There are over 60 types in the hum ...

; English physician

Francis Glisson Francis Glisson (1597 – 14 October 1677Guido Giglioni'Glisson, Francis (1599?–1677)' ''Oxford Dictionary of National Biography'', Oxford University Press, Sept 2004; online edn, May 2006, accessed 31 December 2008) was a British physicia ...

initially identified it two centuries earlier, however it was Oddi who was first able to characterize its physiological properties. Inflammation of the junction of the

duodenum The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear, and the terms anterior intestine or proximal intestine m ...

and

common bile duct The common bile duct, sometimes abbreviated as CBD, is a duct in the gastrointestinal tract of organisms that have a gallbladder. It is formed by the confluence of the common hepatic duct and cystic duct and terminates by uniting with pancreati ...

at the

is referred to as "odditis".

References

Sources

* * * * * * * * * * * Italian physiologists 1864 births 1913 deaths University of Perugia alumni University of Bologna alumni University of Florence alumni University of Genoa faculty Italian anatomists People from Perugia {{italy-med-bio-stub