Rudolph John Anderson
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Rudolph John Anderson (1879–1961) was an
American American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, pe ...
biochemist and a
United States Army The United States Army (USA) is the land service branch of the United States Armed Forces. It is one of the eight U.S. uniformed services, and is designated as the Army of the United States in the U.S. Constitution.Article II, section 2, cla ...
officer.


Biography


Early life

Rudolph Anderson was born in 1879 in
Haina Haina (Kloster) is a municipality in Waldeck-Frankenberg in northwest Hesse, Germany. Geography Location Haina lies in Waldeck-Frankenberg south of Frankenberg and east of Burgwald at the southwest slope of the Kellerwald range. It lies on the ...
,
Sweden Sweden, formally the Kingdom of Sweden,The United Nations Group of Experts on Geographical Names states that the country's formal name is the Kingdom of SwedenUNGEGN World Geographical Names, Sweden./ref> is a Nordic country located on ...
. At the age of 13, he moved to
Boston Boston (), officially the City of Boston, is the state capital and most populous city of the Commonwealth of Massachusetts, as well as the cultural and financial center of the New England region of the United States. It is the 24th- mo ...
where he attended an English grammar school from which he graduated by the time he turned 17. Deciding that continuing his education in
High School A secondary school describes an institution that provides secondary education and also usually includes the building where this takes place. Some secondary schools provide both '' lower secondary education'' (ages 11 to 14) and ''upper seconda ...
was pointless for him, he started working on various industrial jobs during the day while studying during the night. That continued for several years, until, at one of the rubber manufacturing companies, he got a job as a laboratory boy and assistant to a chemist.


Turn of the Century

During the turn of the century, he got a chief chemist position at the manufacturing pharmaceutical company in
New Orleans New Orleans ( , ,New Orleans
Merriam-Webster.
; french: La Nouvelle-Orléans , es, Nuev ...
. In 1906, he graduated from
Tulane University Tulane University, officially the Tulane University of Louisiana, is a private university, private research university in New Orleans, Louisiana. Founded as the Medical College of Louisiana in 1834 by seven young medical doctors, it turned into ...
and got his Ph.D. from
Cornell University Medical College The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York. Weill Cornell Medicine is affiliated with New ...
. In 1909, he came back to Sweden where he applied for doctoral program at University of Uppsala. The university declined his application, and Anderson, discouraged, went to the
University of Berlin Humboldt-Universität zu Berlin (german: Humboldt-Universität zu Berlin, abbreviated HU Berlin) is a German public research university in the central borough of Mitte in Berlin. It was established by Frederick William III on the initiative o ...
where he was accepted to Emil Fischer's laboratory. The laboratory was already full, and he was transported to
Hermann Leuchs Friedrich Hermann Leuchs (8 August 1879 – 2 May 1945) was a German chemist. Life Leuchs studied chemistry at the University of Munich from 1898. He transferred to the University of Berlin and received his Ph.D. there in 1902 under Emil Fischer. ...
laboratory where he was solving the problem on the chemistry of color reaction of combination of
brucine Brucine, is an alkaloid closely related to strychnine, most commonly found in the ''Strychnos nux-vomica'' tree. Brucine poisoning is rare, since it is usually ingested with strychnine, and strychnine is more toxic than brucine. In synthetic ch ...
with
nitric acid Nitric acid is the inorganic compound with the formula . It is a highly corrosive mineral acid. The compound is colorless, but older samples tend to be yellow cast due to decomposition into oxides of nitrogen. Most commercially available nitri ...
. By 1911, Anderson completed the work for his doctoral degree but soon realized that he ran out of money. Fortunately his friend,
Donald Dexter Van Slyke Donald Dexter Van Slyke (March 29, 1883 – May 4, 1971) was a Dutch American biochemist. His achievements included the publication of 317 journal articles and 5 books, as well as numerous awards, among them the National Medal of Science and t ...
, received a letter from his father asking for recommendations. His father was a chief chemist at
Agricultural Experiment Station An agricultural experiment station (AES) or agricultural research station (ARS) is a scientific research center that investigates difficulties and potential improvements to food production and agribusiness. Experiment station scientists work with f ...
in
Geneva Geneva ( ; french: Genève ) frp, Genèva ; german: link=no, Genf ; it, Ginevra ; rm, Genevra is the List of cities in Switzerland, second-most populous city in Switzerland (after Zürich) and the most populous city of Romandy, the French-speaki ...
,
New York New York most commonly refers to: * New York City, the most populous city in the United States, located in the state of New York * New York (state), a state in the northeastern United States New York may also refer to: Film and television * '' ...
and was seeking for a chemist there. Because he was recommended by his friend, Anderson went to Geneva, and soon after it was assigned to study cows
metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cell ...
. Later on he convinced the director that it would be important to know more about
phytic acid Phytic acid is a six-fold dihydrogenphosphate ester of inositol (specifically, of the ''myo'' isomer), also called inositol hexakisphosphate (IP6) or inositol polyphosphate. At physiological pH, the phosphates are partially ionized, resulting ...
before starting to experiment on dairy cows.


World War I

World War I World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...
interrupted his studies in
Berlin Berlin ( , ) is the capital and largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's most populous city, according to population within city limits. One of Germany's sixteen constitue ...
, Germany and he needed to abandon it for a time being. Later on he returned to Geneva where he continued on his work on phytic acid but also expanded his research to include important
fragrance oil Fragrance oils, also known as aroma oils, aromatic oils, and flavor oils, are blended synthetic aroma compounds or natural essential oils that are diluted with a carrier like propylene glycol, vegetable oil, or mineral oil. To allergic or otherwis ...
s that he found in animal urine. He spent several months working side by side with Graham Lusk at
Cornell Medical College The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York. Weill Cornell Medicine is affiliated with NewY ...
where he learned about animal
calorimetry In chemistry and thermodynamics, calorimetry () is the science or act of measuring changes in ''state variables'' of a body for the purpose of deriving the heat transfer associated with changes of its state due, for example, to chemical reacti ...
. During the war, he volunteered and later commissioned as a Captain for the
Sanitary Corps Sanitation refers to public health conditions related to clean drinking water and treatment and disposal of human excreta and sewage. Preventing human contact with feces is part of sanitation, as is hand washing with soap. Sanitation systems ...
in the Division of Food and Nutrition.Marquis Who's Who, Inc. ''Who Was Who in American History, the Military''. Chicago: Marquis Who's Who, 1975. P. 11 In 1919, he was discharged from the army, but before returning to Geneva he completed the necessary requirements for his Ph.D. in Lusk's laboratory.


Post World War I

He was a chief biochemist and professor at
Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach an ...
. Anderson researched dietary
polyneuritis Peripheral neuropathy, often shortened to neuropathy, is a general term describing disease affecting the peripheral nerves, meaning nerves beyond the brain and spinal cord. Damage to peripheral nerves may impair sensation, movement, gland, or or ...
of
poultry Poultry () are domesticated birds kept by humans for their eggs, their meat or their feathers. These birds are most typically members of the superorder Galloanserae (fowl), especially the order Galliformes (which includes chickens, quails, a ...
and the
chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ...
and genetics of grape
pigment A pigment is a colored material that is completely or nearly insoluble in water. In contrast, dyes are typically soluble, at least at some stage in their use. Generally dyes are often organic compounds whereas pigments are often inorganic compo ...
s. He then focused his researched into nucleic acids of plants, but got carried away and left his focus onto the
sterol Sterol is an organic compound with formula , whose molecule is derived from that of gonane by replacement of a hydrogen atom in position 3 by a hydroxyl group. It is therefore an alcohol of gonane. More generally, any compounds that contain the go ...
s present in the oils of plant seeds. In 1926 he was relocated to
Yale University Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the wo ...
where he focused his research on isolating the sterols of the ''tubercle bacillus'' which resulted in the making of
Tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
vaccine. He became professor of chemistry at the same university and was retired as
professor emeritus ''Emeritus'' (; female: ''emerita'') is an adjective used to designate a retired chair, professor, pastor, bishop, pope, director, president, prime minister, rabbi, emperor, or other person who has been "permitted to retain as an honorary title ...
in 1948. He was elected as president of the American Society of Biological Chemists in 1941 and became a member of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
in 1946. The same year, he became a member of the Connecticut Academy of Sciences, and in 1947 he got M.D. degree from the University of Lund in Sweden. In 1948 he was awarded the
Trudeau Medal Trudeau is a surname. Notable people with the surname include: *Trudeau family, a notable Canadian family known in politics, business and film, including: **Charles-Émile Trudeau (1887–1935), Canadian businessman and father of Pierre Trudeau * ...
from the
National Tuberculosis Association National may refer to: Common uses * Nation or country ** Nationality – a ''national'' is a person who is subject to a nation, regardless of whether the person has full rights as a citizen Places in the United States * National, Maryland, ce ...
, and in 1951 became an honorary member of the Connecticut Medical Society. During his lifetime, he was also a managing editor of ''
Journal of Biological Chemistry The ''Journal of Biological Chemistry'' (''JBC'') is a weekly peer-reviewed scientific journal that was established in 1905., jbc.org Since 1925, it is published by the American Society for Biochemistry and Molecular Biology. It covers research in ...
'' from 1937 to 1958.


References


Further reading

* {{DEFAULTSORT:Anderson, Rudolph J. 1879 births 1961 deaths American biochemists Weill Cornell Medical College alumni Tulane University alumni United States Army officers Journal of Biological Chemistry editors Swedish emigrants to the United States