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Rudolf Hugo Nietzki (9 March 1847 – 28 September 1917) was a German chemist who specialized in industrial dyes derived from
coal tar Coal tar is a thick dark liquid which is a by-product of the production of coke and coal gas from coal. It is a type of creosote. It has both medical and industrial uses. Medicinally it is a topical medication applied to skin to treat psoriasi ...
. While a professor at the
University of Basel The University of Basel (Latin: ''Universitas Basiliensis'', German: ''Universität Basel'') is a university in Basel, Switzerland. Founded on 4 April 1460, it is Switzerland's oldest university and among the world's oldest surviving universit ...
in Switzerland he initiated the university's association with to the local chemical industry.


Life

Rudolf Hugo Nietzki was born on 9 March 1847 in Heilsberg, East Prussia (now
Lidzbark Warmiński Lidzbark Warmiński (; german: Heilsberg, ), often shortened to Lidzbark, is a historical town located within the Warmian-Masurian Voivodeship, in northern Poland. It is the capital of Lidzbark County. Lidzbark Warmiński was once the capital of ...
, Poland) to a Protestant family. His father was Carl Johann Emil Nietzki, a priest, rector and writer. He attended the
Königsberg Königsberg (, ) was the historic Prussian city that is now Kaliningrad, Russia. Königsberg was founded in 1255 on the site of the ancient Old Prussian settlement ''Twangste'' by the Teutonic Knights during the Northern Crusades, and was named ...
gymnasium (secondary school), which he left before graduating, then began training as a pharmacist. He studied pharmacy in Zinten (now
Kornevo Kornevo (russian: Корнево) is a rural locality (a village) in Rozhdestvenskoye Rural Settlement, Sobinsky District, Vladimir Oblast, Russia. The population was 24 as of 2010. Geography Kornevo is located 38 km north of Sobinka Sob ...
, Kaliningrad, Russia) and Kreuzburg, Silesia (now
Kluczbork Kluczbork (german: Kreuzburg O.S., szl, Kluczborek) is a town in southern Poland with 23,554 inhabitants (2019), situated in the Opole Voivodeship. It is the capital of Kluczbork County and an important railroad junction. In Kluczbork the major ...
, Poland). In 1865 he qualified as an assistant. He worked as a pharmacist in Hirschberg, Silesia, where he met
Paul Ehrlich Paul Ehrlich (; 14 March 1854 – 20 August 1915) was a Nobel Prize-winning German physician and scientist who worked in the fields of hematology, immunology, and antimicrobial chemotherapy. Among his foremost achievements were finding a cure ...
, who later invented chemotherapy. Nietzki attended the
University of Berlin Humboldt-Universität zu Berlin (german: Humboldt-Universität zu Berlin, abbreviated HU Berlin) is a German public research university in the central borough of Mitte in Berlin. It was established by Frederick William III on the initiative o ...
from 1867 to 1870, where he studied pharmacy. He served as a military pharmacist during the Franco-Prussian War of 1870–71, then returned to the university. Nietzki sat the ''
Staatsexamen The ("state examination" or "exam by state"; pl.: ''Staatsexamina'') is a German government licensing examination that future physicians, dentists, teachers, pharmacists, food chemists, psychotherapists and jurists (i.e., lawyers, judges, public ...
'' to qualify as a pharmacist in 1871, and served as the private assistant of the chemist
August Wilhelm von Hofmann August Wilhelm von Hofmann (8 April 18185 May 1892) was a German chemist who made considerable contributions to organic chemistry. His research on aniline helped lay the basis of the aniline-dye industry, and his research on coal tar laid the g ...
(1818–92). In 1874 he received his PhD in the
University of Göttingen The University of Göttingen, officially the Georg August University of Göttingen, (german: Georg-August-Universität Göttingen, known informally as Georgia Augusta) is a public research university in the city of Göttingen, Germany. Founded ...
. After graduating Nietzki worked as an analyst in the sulfuric acid and soda factory of Matthes & Weber in
Düsseldorf Düsseldorf ( , , ; often in English sources; Low Franconian and Ripuarian: ''Düsseldörp'' ; archaic nl, Dusseldorp ) is the capital city of North Rhine-Westphalia, the most populous state of Germany. It is the second-largest city in th ...
. From 1876 he was assistant to Antoine Paul Nicolas Franchimont (1844–1919) at
Leiden University Leiden University (abbreviated as ''LEI''; nl, Universiteit Leiden) is a Public university, public research university in Leiden, Netherlands. The university was founded as a Protestant university in 1575 by William the Silent, William, Prince o ...
. In 1879 he began to work for Kalle & Co. in Biebrich, Rhineland Palatinate. In a letter to
Heinrich Caro Heinrich Caro (February 13, 1834 in Posen, Prussia Germany now Poznań, Poland – September 11, 1910 in Dresden), was a German chemist. He was a Sephardic Jew. He started his study of chemistry at the Friedrich Wilhelms University and later ...
that year Nietski wrote of his position with this dye company, "I have my own small but nice laboratory and nothing to do with the manufacturing; moreover I shall have the same position as you have in Ludwigshafen: That of an inventor!" In 1880 Nietzki married Minna Bickerle. He moved to
Basel , french: link=no, Bâlois(e), it, Basilese , neighboring_municipalities= Allschwil (BL), Hégenheim (FR-68), Binningen (BL), Birsfelden (BL), Bottmingen (BL), Huningue (FR-68), Münchenstein (BL), Muttenz (BL), Reinach (BL), Riehen (BS ...
, Switzerland, where he worked for Geigy. Nietzki studied for his
habilitation Habilitation is the highest university degree, or the procedure by which it is achieved, in many European countries. The candidate fulfills a university's set criteria of excellence in research, teaching and further education, usually including a ...
under the Swiss chemist
Jules Piccard Jules Piccard, also known as Julius Piccard (20 September 1840, in Lausanne – 11 April 1933, in Lausanne) was a Swiss chemist. He was the father of twins Auguste Piccard (1884–1962) and Jean Felix Piccard (1884–1963), both renowned balloonis ...
(1840–1933) in 1884 at the
University of Basel The University of Basel (Latin: ''Universitas Basiliensis'', German: ''Universität Basel'') is a university in Basel, Switzerland. Founded on 4 April 1460, it is Switzerland's oldest university and among the world's oldest surviving universit ...
. He was appointed Associate Professor of Chemistry at Basel in 1887. In 1888 Nietzki wrote a highly regarded textbook on organic dyes. In 1895 he became Professor of Chemistry. Nietzki specialized in industrially useful dyes, and initiated the University of Basel's association with the chemical industry. He worked in his private laboratory, subsidized by the state, in the Kleinbasel ice factory. He was assisted by
Friedrich Fichter Friedrich Fichter (6 July 1869 – 1952) was a professor of inorganic chemistry at the University of Basel. His main field of interest was electrochemistry. He initiated the founding of the scientific journal ''Helvetica Chimica Acta''. Life Fi ...
as inorganic chemist and
Hans Rupe Johan Hermann Wilhelm Rupe (October 9, 1866, in Basel – January 12, 1951) was a professor of organic chemistry at the University of Basel. His main field of interest was terpenes and campher as well as optical activity. Life Rupe was bo ...
as organic chemist. Nietzki resigned due to illness in 1911. He was made Professor Emeritus by the university. He died on 28 September 1917 in
Neckargemünd Neckargemünd ( pfl, Neggergmin) is a town in Germany, in the district of Rhein-Neckar-Kreis, state of Baden-Württemberg. It lies on the Neckar, 10 km upriver from Heidelberg at the confluence with the river Elsenz. This confluence of the t ...
, Baden-Württemberg.


Work

Nietzki played a leading role in the development of a new class of synthetic dyes derived from
coal tar Coal tar is a thick dark liquid which is a by-product of the production of coke and coal gas from coal. It is a type of creosote. It has both medical and industrial uses. Medicinally it is a topical medication applied to skin to treat psoriasi ...
. He made his name through his work on
quinone The quinones are a class of organic compounds that are formally "derived from aromatic compounds
uch as benzene or naphthalene Uch ( pa, ; ur, ), frequently referred to as Uch Sharīf ( pa, ; ur, ; ''"Noble Uch"''), is a historic city in the southern part of Pakistan's Punjab province. Uch may have been founded as Alexandria on the Indus, a town founded by Alexand ...
by conversion of an even number of –CH= groups into –C(=O)– groups with any necessary rearrangement of double ...
derivatives and
azo dye Azo dyes are organic compounds bearing the functional group R−N=N−R′, in which R and R′ are usually aryl and substituted aryl groups. They are a commercially important family of azo compounds, i.e. compounds containing the C-N=N ...
s. In 1876 he analyzed the synthetic dye ''Anilinschwarz'' (
Aniline Aniline is an organic compound with the formula C6 H5 NH2. Consisting of a phenyl group attached to an amino group, aniline is the simplest aromatic amine In organic chemistry, an aromatic amine is an organic compound consisting of an aroma ...
black). In 1877 he discovered that indamine dyes were formed in the oxidative coupling of p-diamines and monoamines. He synthesized nitranil acid and developed a simple method for the preparation of p-benzoquinone. In 1878 he created "
Biebrich scarlet Biebrich scarlet (C.I. 26905) is a molecule used in Lillie's trichrome. The dye was created in 1878 by the German chemist Rudolf Nietzki. Biebrich scarlet dyes are used to color hydrophobic materials like fats and oils. The dye is an illegal dye ...
" the first tetra azo dye. While working at Kalle & Co. Nietzki recognized that
Raphael Meldola Raphael Meldola FRS (19 July 1849 – 16 November 1915) was a British chemist and entomologist. He was Professor of Organic Chemistry in the University of London, 1912–15. Life Born in Islington, London, he was descended from Raphael Me ...
's synthetic dye, Meldola's Blue, was a member of the
oxazine Oxazines are heterocyclic compounds containing one oxygen and one nitrogen atom in a doubly unsaturated six-membered ring. Isomers exist depending on the relative position of the heteroatoms and relative position of the double bonds. By extension ...
class.


Publications

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Notes


Sources

* * * * * {{DEFAULTSORT:Nietzki, Rudolf Hugo 1847 births 1917 deaths 19th-century German chemists 20th-century German chemists People from Lidzbark Warmiński