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Rubidium-82 chloride is a form of
rubidium chloride Rubidium chloride is the chemical compound with the formula RbCl. This alkali metal halide salt is composed of rubidium and chlorine, and finds diverse uses ranging from electrochemistry to molecular biology. Structure In its gas phase, RbCl is d ...
containing a radioactive isotope of
rubidium Rubidium is the chemical element with the symbol Rb and atomic number 37. It is a very soft, whitish-grey solid in the alkali metal group, similar to potassium and caesium. Rubidium is the first alkali metal in the group to have a density higher ...
. It is marketed under the brand name Cardiogen-82 by
Bracco Diagnostics The Bracco Group is an Italian multinational active in the healthcare sector with more than 3,300 employees worldwide, which operates in a variety of business areas. *Diagnostic imaging, with products for X-ray imaging, including computed tomog ...
for use in
Myocardial perfusion imaging Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle (myocardium). It evaluates many heart conditions, such as coronary artery disease (CAD), h ...
. It is rapidly taken up by
heart muscle Cardiac muscle (also called heart muscle, myocardium, cardiomyocytes and cardiac myocytes) is one of three types of vertebrate muscle tissues, with the other two being skeletal muscle and smooth muscle. It is an involuntary, striated muscle tha ...
cells, and therefore can be used to identify regions of heart muscle that are receiving poor
blood flow Hemodynamics or haemodynamics are the dynamics of blood flow. The circulatory system is controlled by homeostatic mechanisms of autoregulation, just as hydraulic circuits are controlled by control systems. The hemodynamic response continuously m ...
in a technique called
PET A pet, or companion animal, is an animal kept primarily for a person's company or entertainment rather than as a working animal, livestock, or a laboratory animal. Popular pets are often considered to have attractive appearances, intelligence, ...
perfusion imaging. The
half-life Half-life (symbol ) is the time required for a quantity (of substance) to reduce to half of its initial value. The term is commonly used in nuclear physics to describe how quickly unstable atoms undergo radioactive decay or how long stable ato ...
of the
rubidium-82 Rubidium-82 (82Rb) is a radioactive isotope of rubidium. 82Rb is widely used in myocardial perfusion imaging. This isotope undergoes rapid uptake by myocardiocytes, which makes it a valuable tool for identifying myocardial ischemia in Positron Em ...
is only 1.27 minutes; it is normally produced at the place of use by rubidium generators.


References


Further reading

* (Note: only about 1/2 page on Rb-generator) * * Rubidium compounds Chlorides Metal halides Alkali metal chlorides Radiopharmaceuticals {{Pharma-stub