Roy Markham
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Roy Markham FRS (29 January 1916 – 16 November 1979) was a British plant virologist who served as the fifth director of the
John Innes Centre The John Innes Centre (JIC), located in Norwich, Norfolk, England, is an independent centre for research and training in plant and microbial science founded in 1910. It is a registered charity (No 223852) grant-aided by the Biotechnology and B ...
from 1967 until his death in 1979.


Early life

Markham was born in London in 1916. His family relocated to
Bridge of Allan Bridge of Allan ( sco, Brig Allan, gd, Drochaid Ailein), also known colloquially as ''Bofa'', is a town in the Stirling council area in Scotland, just north of the city of Stirling. Overlooked by the National Wallace Monument, it lies on the A ...
in Scotland while he was young and returned to London in 1925. He attended several schools in England and in
Magdeburg Magdeburg (; nds, label=Low Saxon, Meideborg ) is the capital and second-largest city of the German state Saxony-Anhalt. The city is situated at the Elbe river. Otto I, the first Holy Roman Emperor and founder of the Archdiocese of Magdebur ...
, Germany, but he disliked all of these until he started at St Paul's School in London, aged 15. During his years at St Paul's, he enjoyed his annual summer holidays at his family's house in
Ventnor Ventnor () is a seaside resort and civil parish established in the Victorian era on the southeast coast of the Isle of Wight, England, from Newport. It is situated south of St Boniface Down, and built on steep slopes leading down to the sea. ...
on the
Isle of Wight The Isle of Wight ( ) is a county in the English Channel, off the coast of Hampshire, from which it is separated by the Solent. It is the largest and second-most populous island of England. Referred to as 'The Island' by residents, the Isle of ...
. It was there that he met Margaret Mullen, whom he later married.


Research career

He joined
Christ's College, Cambridge Christ's College is a constituent college of the University of Cambridge. The college includes the Master, the Fellows of the College, and about 450 undergraduate and 170 graduate students. The college was founded by William Byngham in 1437 as ...
in 1935, specialising in biochemistry for the second part of his degree. He graduated in 1938 with an upper second class degree and became a PhD student in the laboratory of
Norman Pirie Norman Wingate (Bill) Pirie FRS (1 July 1907 – 29 March 1997), was a British biochemist and virologist who, along with Frederick Bawden, discovered that a virus can be crystallized by isolating tomato bushy stunt virus in 1936. This was a ...
, with whom he had worked as an undergraduate. For his thesis, which he completed in 1944, he worked on the isolation of plant viruses, including
tomato bushy stunt virus Tomato bushy stunt virus (TBSV) is a virus of the tombusvirus family. It was first reported in tomatoes in 1935 and primarily affects vegetable crops, though it is not generally considered an economically significant plant pathogen. Depending up ...
and
tobacco mosaic virus ''Tobacco mosaic virus'' (TMV) is a positive-sense single-stranded RNA virus species in the genus ''Tobamovirus'' that infects a wide range of plants, especially tobacco and other members of the family Solanaceae. The infection causes characteri ...
(TMV). Markham continued working in Cambridge following his PhD, joining the Molteno Institute to work on the biochemistry of
RNA Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid ( DNA) are nucleic acids. Along with lipids, proteins, and carbohydra ...
s. One of his contemporaries at Cambridge was
James Watson James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist, and zoologist. In 1953, he co-authored with Francis Crick the academic paper proposing the double helix structure of the DNA molecule. Watson, Crick and ...
, who in his book, ''
The Double Helix ''The Double Helix: A Personal Account of the Discovery of the Structure of DNA'' is an autobiographical account of the discovery of the double helix structure of DNA written by James D. Watson and published in 1968. It has earned both critical ...
'', recalls seeking TMV for an experiment: He returned to work on the structure of plant viruses at the end of the 1950s. He was particularly interested in using
electron microscopy An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a hi ...
to look at virus architecture.


Virus Research Unit

In 1960, Markham became director of the
Agricultural Research Council The Agricultural and Food Research Council (AFRC) was a British Research Council responsible for funding and managing scientific and technological developments in farming and horticulture. History The AFRC was formed in 1983 from its predecessor, ...
(ARC) Virus Research Unit in Cambridge, succeeding Kenneth Smith. The research station was first opened in 1927 and became a research unit of the ARC in 1948.


John Innes Institute

The John Innes Institute moved from
Bayfordbury Bayfordbury, Hertfordshire, is a large Grade II* listed country house with surrounding parkland, and the location of a University of Hertfordshire campus, housing its biology/geography field station and observatory. History of Bayfordbury Bayford ...
, Hertfordshire to
Norwich Norwich () is a cathedral city and district of Norfolk, England, of which it is the county town. Norwich is by the River Wensum, about north-east of London, north of Ipswich and east of Peterborough. As the seat of the See of Norwich, with ...
, Norfolk in 1967, following its association with the newly-formed
University of East Anglia The University of East Anglia (UEA) is a public research university in Norwich, England. Established in 1963 on a campus west of the city centre, the university has four faculties and 26 schools of study. The annual income of the institution f ...
(UEA). Before the institute's move was completed, its director, Kenneth S Doods, resigned to take up a position with the
Food and Agriculture Organization The Food and Agriculture Organization of the United Nations (FAO)french: link=no, Organisation des Nations unies pour l'alimentation et l'agriculture; it, Organizzazione delle Nazioni Unite per l'Alimentazione e l'Agricoltura is an intern ...
in Turkey. Roy Markham was appointed as his successor, and he, along with the Virus Research Unit, moved to Norwich in October 1967. Markham played an important role in establishing the institute at its new location. Its move from Bayfordbury had led the majority of the institute's staff to find employment elsewhere, and only 17 staff members moved to Norwich in 1967. However, under Markham's directorship, the institute grew and was reorganised into four new departments: Cell Biology, Genetics, Applied Genetics and Ultrastructural Studies. Markham also persuaded the trustees of the John Innes Foundation, which owned the land on which the institute was built, to provide a large lecture hall and recreational facilities, including a swimming pool, for the staff. He took great interest in developing much of the technology at the new institute and listed himself under the 'Electronics Section' in the institute's annual reports.


Death

Roy Markham suffered a heart attack in 1978, from which he recovered. However, he later developed bowel cancer and died on 16 November 1979.


References

{{DEFAULTSORT:Markham, Roy 1916 births 1979 deaths People educated at St Paul's School, London Alumni of Christ's College, Cambridge Academics of the University of East Anglia Fellows of the Royal Society New Naturalist writers British botanists