The following highways are numbered 780:

Australia

Canada

Saskatchewan Highway 780 Saskatchewan ( ; ) is a province in western Canada, bordered on the west by Alberta, on the north by the Northwest Territories, on the east by Manitoba, to the northeast by Nunavut, and on the south by the U.S. states of Montana and North Dako ...

United States

Interstate 780 Interstate 780 (I-780) is an east–west auxiliary Interstate Highway in the San Francisco Bay Area of Northern California. It runs from Curtola Parkway and Lemon Street in Vallejo to I-680 just north of the Benicia–Martinez Bridge in B ...

Florida State Road 780 State Road 780 (SR 780), known as Fruitville Road, is a east–west street in Sarasota, Florida. The western terminus is an intersection with US 301/ SR 683 (Washington Boulevard). The eastern terminus is east of an interchange with Interstate 7 ...

Nevada State Route 780 (former) * Ohio State Route 780 (former) * PA-780

Pennsylvania Route 780 Pennsylvania Route 780 (PA 780) is an state highway located in Westmoreland County, Pennsylvania, Westmoreland County, Pennsylvania. The western terminus is at Pennsylvania Route 56, PA 56/Pennsylvania Route 366, PA 366 in New Kensington, Pennsy ...

(former) * PA-780

(current) * Ellipse sign 780

Puerto Rico Highway 780 * Circle sign 780

Virginia State Route 780 {{Road index, 780