Roshan Cools (born 10 June 1975) is a Professor of

Cognitive Neuropsychiatry Cognitive neuropsychiatry is a growing multidisciplinary field arising out of cognitive psychology and neuropsychiatry that aims to understand mental illness and psychopathology in terms of models of normal psychological function. A concern wit ...

Radboud University Nijmegen Radboud University (abbreviated as RU, nl, Radboud Universiteit , formerly ''Katholieke Universiteit Nijmegen'') is a public research university located in Nijmegen, the Netherlands. The university bears the name of Saint Radboud, a 9th century D ...

. She is interested in the motivational and cognitive control of human behaviour and how it is impacted by

neuromodulation Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons. Neuromodulators typically bind to metabotropic, G-protein coupled receptors (GPCRs) to initiate a second m ...

. She was elected to the

Royal Netherlands Academy of Arts and Sciences The Royal Netherlands Academy of Arts and Sciences ( nl, Koninklijke Nederlandse Akademie van Wetenschappen, abbreviated: KNAW) is an organization dedicated to the advancement of science and literature in the Netherlands. The academy is housed ...

in 2018.

Early life and education

Cools was born in the

Netherlands ) , anthem = ( en, "William of Nassau") , image_map = , map_caption = , subdivision_type = Sovereign state , subdivision_name = Kingdom of the Netherlands , established_title = Before independence , established_date = Spanish Netherl ...

. Her father was a brain scientist and she recalls conversations about the brain and dopamine at the dinner table. Cools studied neuropsychology at the

University of Groningen The University of Groningen (abbreviated as UG; nl, Rijksuniversiteit Groningen, abbreviated as RUG) is a Public university#Continental Europe, public research university of more than 30,000 students in the city of Groningen (city), Groningen in ...

. She graduated

cum laude Latin honors are a system of Latin phrases used in some colleges and universities to indicate the level of distinction with which an academic degree has been earned. The system is primarily used in the United States. It is also used in some Sou ...

in 1998 and moved to the

United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and North ...

. Cools worked with

Trevor Robbins Trevor William Robbins CBE FRS FMedSci is a Professor of cognitive neuroscience and former Head of the Department of Psychology at the University of Cambridge. Robbins interests are in the fields of cognitive neuroscience, behavioural neuros ...

at the University of Cambridge on

Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...

for her PhD awarded in 2002.

Career and research

After earning her doctoral degree she worked as a Junior Research fellow and

Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...

Dorothy Hodgkin Fellow at

St John's College, Cambridge St John's College is a Colleges of the University of Cambridge, constituent college of the University of Cambridge founded by the House of Tudor, Tudor matriarch Lady Margaret Beaufort. In constitutional terms, the college is a charitable corpo ...

. She moved to the

University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant u ...

, where she spent two years as a

postdoctoral A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to p ...

fellow with Mark D'Esposito. She won a

Royal Society University Research Fellowship __NOTOC__ The Royal Society University Research Fellowship (URF) is a research fellowship awarded to outstanding early career scientists in the United Kingdom who are judged by the Royal Society to have the potential to become leaders in their fie ...

which was based at the University of Cambridge. In 2007 Cools moved back to the

, where she worked in the Centre for Cognitive Neuroimaging in the Donders Institute for Brain. At the

Cools leads the Motivational and Cognitive Control Lab. She was promoted to Full Professor in 2011. She studies the role of

neuromodulators Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons. Neuromodulators typically bind to metabotropic, G-protein coupled receptors (GPCRs) to initiate a second m ...

(

dopamine Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic compound, organic chemical of the catecholamine and phenethylamine families. Dopamine const ...

and

serotonin Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vas ...

) in the control of decision making. She showed that the genes associated with dopamine impact how we learn from the long-term consequences of decisions, whilst

is more strongly associated with short-term choices. She has also shown that people who gamble have increased levels of dopamine in their brains, whilst people who are addicted to drugs have average or lower than normal levels of dopamine. She used her expertise in decision making to show that dominant individuals are avid social learners; whilst they value their independence, they rely on social learning in complex decision making tasks. She is interested in advancing understanding of

neuropsychiatric Neuropsychiatry or Organic Psychiatry is a branch of medicine that deals with psychiatry as it relates to neurology, in an effort to understand and attribute behavior to the interaction of neurobiology and social psychology factors. Within neurop ...

disorders, including

impulse control disorder Impulse-control disorder (ICD) is a class of psychiatric disorders characterized by impulsivity – failure to resist a temptation, an urge, or an impulse; or having the inability to not speak on a thought. Many psychiatric disorders feature imp ...

Attention Deficit Hyperactivity Disorder Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by excessive amounts of inattention, hyperactivity, and impulsivity that are pervasive, impairing in multiple contexts, and otherwise age-inap ...

(

ADHD Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by excessive amounts of inattention, hyperactivity, and impulsivity that are pervasive, impairing in multiple contexts, and otherwise age-inapp ...

) and

. She demonstrated that people suffering from

schizophrenia Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdra ...

have motivation deficits from very early stages of their diagnoses, which are unrelated to their treatments. Cools is interested in the mechanisms by which we exert willpower and what happens to willpower in people with

. She believes that the goals that are characteristic of human behaviour can be classified as motivational (i.e. maximise reward) and cognitive (i.e. complete task). Her research considers the interactions between motivational and cognitive control. Cools demonstrated that the neural networks of

psychopathic Psychopathy, sometimes considered synonymous with sociopathy, is characterized by persistent antisocial behavior, impaired empathy and remorse, and bold, disinhibited, and egotistical traits. Different conceptions of psychopathy have been ...

criminals are different to that or normal people, with a strong focus on

reward Reward may refer to: Places * Reward (Shelltown, Maryland), a historic home in Shelltown Maryland * Reward, California (disambiguation) * Reward-Tilden's Farm, a historic home in Chestertown Maryland Arts, entertainment, and media * "Rewa ...

and a lack of

self-control Self-control, an aspect of inhibitory control, is the ability to regulate one's emotions, thoughts, and behavior in the face of temptations and impulses. As an executive function, it is a cognitive process that is necessary for regulating one's b ...

. She was appointed to the Advisory Council for Science and Technology Policy to the

Dutch government The politics of the Netherlands take place within the framework of a parliamentary representative democracy, a constitutional monarchy, and a decentralised unitary state.''Civil service systems in Western Europe'' edited by A. J. G. M. Bekke, ...

in 2014.

Awards and honours

Her awards and honours include; * 2012 James McDonnell Scholar Award * 2013 Elected Fellow of the

Association for Psychological Science The Association for Psychological Science (APS), previously the American Psychological Society, is an international non-profit organization whose mission is to promote, protect, and advance the interests of scientifically oriented psychology in ...

* 2015

Netherlands Organisation for Scientific Research The Dutch Research Council (NWO, Dutch: Nederlandse Organisatie voor Wetenschappelijk Onderzoek) is the national research council of the Netherlands. NWO funds thousands of top researchers at universities and institutes and steers the course of ...

Vici Award * 2016 Elected Member of the

Academia Europaea The Academia Europaea is a pan-European Academy of Humanities, Letters, Law, and Sciences. The Academia was founded in 1988 as a functioning Europe-wide Academy that encompasses all fields of scholarly inquiry. It acts as co-ordinator of Europea ...

* 2017

Ammodo Award in Social Sciences * 2018 Elected Member of the

International Neuropsychological Society The International Neuropsychological Society is an international non-profit learned society dedicated to promoting research in neuropsychology. It was established in 1967 with only a few members, with its membership growing to about 5,000 by 2015. ...

* 2018 Elected Member of the

* 2019 Elected to the

Faculty of 1000 F1000 (formerly "Faculty of 1000") is an open research publisher for scientists, scholars, and clinical researchers. F1000 offers a different research evaluation service from standard academic journals by offering peer-review after, rather than ...

She delivered a

TED Talk TED Conferences, LLC (Technology, Entertainment, Design) is an American-Canadian non-profit media organization that posts international talks online for free distribution under the slogan "ideas worth spreading". TED was founded by Richard Sau ...

in 2013.

Selected publications

Her publications include; * * *

References

{{DEFAULTSORT:Cools, Roshan Academic staff of Radboud University Nijmegen University of Groningen alumni Alumni of the University of Cambridge Alumni of St John's College, Cambridge Members of Academia Europaea Members of the Royal Netherlands Academy of Arts and Sciences Dutch neuroscientists University of California, Berkeley alumni 1975 births Living people