Silvana Romina Goldszmid is an Argentine-American biologist researching tumor immunology. She is an NIH Stadtman Investigator at the

National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...

Education

Romina Goldszmid completed a M.S. in biochemistry and a Ph.D. in tumor immunology working on

dendritic Dendrite derives from the Greek word "dendron" meaning ( "tree-like"), and may refer to: Biology *Dendrite, a branched projection of a neuron *Dendrite (non-neuronal), branching projections of certain skin cells and immune cells Physical * Dendr ...

cell-based vaccines for melanoma immunotherapy from the

University of Buenos Aires The University of Buenos Aires ( es, Universidad de Buenos Aires, UBA) is a public university, public research university in Buenos Aires, Argentina. Established in 1821, it is the premier institution of higher learning in the country and one o ...

, part of which was performed as a visiting scholar in the laboratory of

Ralph M. Steinman Ralph Marvin Steinman (January 14, 1943 – September 30, 2011) was a Canadian physician and medical researcher at Rockefeller University, who in 1973 discovered and named dendritic cells while working as a postdoctoral fellow in the labora ...

at the

Rockefeller University The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...

. In 2004, she came to the

National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...

to conduct postdoctoral research in infectious disease immunology with Alan Sher in the Laboratory of Parasitic Diseases (LPD) at the National Institute of Allergy and Infectious Diseases (NIAID).

Career and research

In 2009, Goldszmid returned to tumor immunology, joining laboratory of at CCR, NCI, as a staff scientist. In 2015, she became an NIH Earl Stadtman Investigator in the Laboratory of Integrative Cancer Immunology and an adjunct investigator in LPD, NIAID. In 2019, she won a Presidential Early Career Award for Scientists and Engineers. Goldszmid has a long-standing interest in understanding the mechanisms governing the development, functional maturation and dynamics of the mononuclear phagocyte cellular network .g. dendritic cells, monocytes and macrophagesthat plays an instrumental role in host defense. In particular, her research focuses on linking the microbiome, mononuclear phagocyte development, and cancer and infectious diseases with the ultimate goal of identifying new potential therapeutic interventions to improve cancer treatment. Goldszmid and her colleagues showed for the first time that the gut microbiota control the response to cancer immunotherapy and chemotherapy by modulating myeloid-cell functions in the tumor microenvironment.

References

{{DEFAULTSORT:Goldszmid, Romina American immunologists Argentine biologists 21st-century American biologists 21st-century Argentine scientists 21st-century American women scientists American women biologists Argentine women scientists Women medical researchers American medical researchers Argentine medical researchers Cancer researchers National Institutes of Health people Argentine emigrants to the United States University of Buenos Aires alumni Living people Year of birth missing (living people)