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Major-General Major general (abbreviated MG, maj. gen. and similar) is a military rank used in many countries. It is derived from the older rank of sergeant major general. The disappearance of the "sergeant" in the title explains the apparent confusion of a ...
Sir Robert McCarrison, CIE, FRCP (15 March 1878 – 18 May 1960) was a
Northern Ireland Northern Ireland ( ga, Tuaisceart Éireann ; sco, label= Ulster-Scots, Norlin Airlann) is a part of the United Kingdom, situated in the north-east of the island of Ireland, that is variously described as a country, province or region. Nort ...
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
and
nutritionist A nutritionist is a person who advises others on matters of food and nutrition and their impacts on health. Some people specialize in particular areas, such as sports nutrition, public health, or animal nutrition, among other disciplines. In many ...
in the
Indian Medical Service The Indian Medical Service (IMS) was a military medical service in British India, which also had some civilian functions. It served during the two World Wars, and remained in existence until the independence of India in 1947. Many of its officer ...
, who was made a Companion of the Indian Empire (CIE) in 1923, (See p.3946 for list heading) received a knighthood in July 1933, and was appointed as Honourable Physician to the King in 1935. McCarrison was born in
Portadown Portadown () is a town in County Armagh, Northern Ireland. The town sits on the River Bann in the north of the county, about southwest of Belfast. It is in the Armagh City, Banbridge and Craigavon Borough Council area and had a population of a ...
, in
County Armagh County Armagh (, named after its county town, Armagh) is one of the six counties of Northern Ireland and one of the traditional thirty-two counties of Ireland. Adjoined to the southern shore of Lough Neagh, the county covers an area of and ha ...
,
Northern Ireland Northern Ireland ( ga, Tuaisceart Éireann ; sco, label= Ulster-Scots, Norlin Airlann) is a part of the United Kingdom, situated in the north-east of the island of Ireland, that is variously described as a country, province or region. Nort ...
. He qualified in Medicine at
Queen's College, Belfast , mottoeng = For so much, what shall we give back? , top_free_label = , top_free = , top_free_label1 = , top_free1 = , top_free_label2 = , top_free2 = , established = , closed = , type = Public research university , parent = ...
in 1900. He joined the
Indian Medical Service The Indian Medical Service (IMS) was a military medical service in British India, which also had some civilian functions. It served during the two World Wars, and remained in existence until the independence of India in 1947. Many of its officer ...
and was posted as Medical Officer to Indian troops guarding the mountainous Northern Frontiers. He was promoted to Captain in January 1904, to Major in July 1912, Lieutenant-Colonel in January 1918, (List heading: "To be Brevet Lieutenant-Colonerl" is on p.10) Colonel from 1929, and to Major-General in July 1933. He retired from the Indian Medical Service on 19 August 1935. McCarrison's research in India on the cause of
goitre A goitre, or goiter, is a swelling in the neck resulting from an enlarged thyroid gland. A goitre can be associated with a thyroid that is not functioning properly. Worldwide, over 90% of goitre cases are caused by iodine deficiency. The term is ...
won widespread recognition and in 1913 he was promoted to do research. In 1928 he became Director of Nutritional Research in India, where he remained until his retirement from the Indian Medical Service in 1935, when he returned to
England England is a country that is part of the United Kingdom. It shares land borders with Wales to its west and Scotland to its north. The Irish Sea lies northwest and the Celtic Sea to the southwest. It is separated from continental Europe b ...
, settling at
Oxford Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the ...
.


Pioneer in nutrition research

McCarrison carried out the very first experiments to demonstrate the effect of
nutrition Nutrition is the biochemical and physiological process by which an organism uses food to support its life. It provides organisms with nutrients, which can be metabolized to create energy and chemical structures. Failure to obtain sufficient n ...
on the
epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidenc ...
of disease. McCarrison is credited with being the first to experimentally demonstrate the effect of deficient dietaries upon animal tissues and organs. He also carried out human experiments aimed at identifying the cause of goitre, and included himself as one of the experimental subjects. Much of McCarrison's work was pioneering. His 1921 book ''Studies in Deficiency Disease'' was considered notable at the time, being published at a time when knowledge of vitamins and their role in nutrition was crystallizing. McCarrison himself noted that prior to publication of his studies on the pathogenesis of deficiency disease "no systemic ''post-mortem'' examination of animals fed on food deficient in
vitamin B B vitamins are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. Though these vitamins share similar names (B1, B2, B3, etc.), they are chemically distinct compounds that often coex ...
had ever been made; the histopathological effects of such food on the various systems of the body were wholly unknown; above all, its effects on the gastro-intestinal tract and the organs of digestion and assimilation, and the significance of these effects for clinical medicine, were wholly unsuspected". At age 23, McCarrison went to India, where he spent 30 years on nutritional problems.. Retrieved 12 August 2010 He attained the rank of major-general in the Indian Medical Service, and founded the Nutritional Research Laboratories in
Coonoor Coonoor, natively spelt as Kunnur (), is a Taluk and a municipality of the Nilgiris district in the Indian State of Tamil Nadu. As of 2011, the town had a population of 45,494. Demographics According to 2011 census, Coonoor had a populatio ...
. After retiring from the Indian Medical Service in 1935, he gave a series of Cantor lectures at the Royal Society of Arts, about the influence of diet on health. This comprised three lectures delivered on successive Mondays at the Society. The first lecture focused on the processes of nutrition; the second, on food essentials and their relationship to bodily structure and function; the third on disease prevention and physique improvement by attention to diet. The lectures were subsequently published in book form under the title ''Nutrition and Health'', and at the time of the third edition in 1962, were still not seen as "dated", with the advances of the preceding 25 years largely filling the details of the principles previously recognised by McCarrison. "McCarrison's work on goitre,
cretinism Congenital iodine deficiency syndrome is a medical condition present at birth marked by impaired physical and mental development, due to insufficient thyroid hormone (hypothyroidism) often caused by insufficient dietary iodine during pregnancy. It ...
, and
thyroid The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans it is in the neck and consists of two connected lobes. The lower two thirds of the lobes are connected by a thin band of tissue called the thyroid isthmus. The thy ...
, begun in the western Himalayas in 1902, generated scores of scientific publications during the following thirty-five years", While McCarrison's work is often considered the start of serious studies of goitre and cretinism in
South Asia South Asia is the southern subregion of Asia, which is defined in both geographical and ethno-cultural terms. The region consists of the countries of Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka.;;;;;;;; ...
, it was preceded by that of Commissioner
David Scott David Randolph Scott (born June 6, 1932) is an American retired test pilot and NASA astronaut who was the seventh person to walk on the Moon. Selected as part of the third group of astronauts in 1963, Scott flew to space three times and c ...
at Rangur in north-east India around 1825, and was investigated by Mountford Bramley at
Kathmandu , pushpin_map = Nepal Bagmati Province#Nepal#Asia , coordinates = , subdivision_type = Country , subdivision_name = , subdivision_type1 = Province , subdivision_name1 = Bagmati Prov ...
in 1832. In 1918, McCarrison founded the ''Beri-Beri Enquiry Unit'' in a single room laboratory at the
Pasteur Institute The Pasteur Institute (french: Institut Pasteur) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines f ...
in Conoor, India. He was invalided to Britain from 1920–1922, and in 1923 the enquiry was axed on financial grounds. It was restored two years later as the ''Deficiency Disease Inquiry'', which McCarrison headed from 1925-1929. Around 1928-29, this developed further into the Nutrition Research Laboratories (NRL. Renamed the National Institute of Nutrition in 1969), with McCarrison as its first Director, until his retirement in 1935. In 1926, as head of the ''Deficiency Diseases Inquiry'', McCarrison submitted written and oral evidence on
malnutrition Malnutrition occurs when an organism gets too few or too many nutrients, resulting in health problems. Specifically, it is "a deficiency, excess, or imbalance of energy, protein and other nutrients" which adversely affects the body's tissues a ...
to the ''Royal Commission on Agriculture in India''. (Full text at Internet Archive The primary objective of McCarrison's submission was to indicate the significance of malnutrition "as a cause of physical inefficiency and ill-health among the masses in India"; the relationship between nutrition and agriculture; and "the necessity for closer co-ordination of nutritional, medical, veterinary and agricultural research" in India.McCarrison, Lieut.-Colonel R (1928), p.95 McCarrison's submission had impact. "A decade later, when the Commission's chairman,
Lord Linlithgow Marquess of Linlithgow, in the County of Linlithgow or West Lothian, is a title in the Peerage of the United Kingdom. It was created on 23 October 1902 for John Hope, 7th Earl of Hopetoun. The current holder of the title is Adrian Hope. This ...
, became Viceroy of India he showed a personal interest in nutrition, pushing it to the top of the research agenda. In 1936 a Nutrition Advisory Committee was established and roughly a tenth of IRFA's annual grants went to fund nutrition research at Coonoor and
Calcutta Kolkata (, or , ; also known as Calcutta , List of renamed places in India#West Bengal, the official name until 2001) is the Capital city, capital of the Indian States and union territories of India, state of West Bengal, on the eastern ba ...
".


Retirement from India

After
the Second World War World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposing ...
, from 1945 to 1955, McCarrison served as director of postgraduate
medical education Medical education is education related to the practice of being a medical practitioner, including the initial training to become a physician (i.e., medical school and internship (medical), internship) and additional training thereafter (e.g., Re ...
at
Oxford University Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the ...
.


Personal life

In 1906 he married Helen Stella Johnston, to whom he was still married at the time of his death.


Legacy

* The National Institute of Nutrition in
Hyderabad Hyderabad ( ; , ) is the capital and largest city of the Indian state of Telangana and the ''de jure'' capital of Andhra Pradesh. It occupies on the Deccan Plateau along the banks of the Musi River (India), Musi River, in the northern part ...
, India, continues to pay tribute to is origins in 1928 under McCarrison. * McCarrison is grouped, along with
Sir Albert Howard Sir Albert Howard (8 December 187320 October 1947) was an English botanist. His academic background might have been botany. While working in India he was generally considered a Pathologist; this more than likely being the reason for his consist ...
and
Richard St. Barbe Baker Richard St. Barbe Baker , Hon. LL.D. F.I.A.L., For.Dip.Cantab., ACF (9 October 1889 – 9 June 1982) was an English biologist and botanist, environmental activist and author, who contributed greatly to worldwide reforestation efforts. As a ...
, as one of three progenitors of the
organic agriculture Organic farming, also known as ecological farming or biological farming,Labelling, article 30 o''Regulation (EU) 2018/848 of the European Parliament and of the Council of 30 May 2018 on organic production and labelling of organic products and re ...
movement.


McCarrison Society

In 1966, a group of doctors, dentists and veterinarians, interested in the promotion of nutrition and health, founded the McCarrison Society in honour of his efforts, with a Scottish group established in 1981 due to both travel logistics and differing needs in the Scottish population. The Society aims "to assemble scientific knowledge on nutrition and health that is free from economic and political pressures with the object of securing the physical and mental health of future generations". The Society meetings sometimes raise questions with elusive answers, with speakers presenting material based on scanty, often anectdotal data, inviting criticism that it is "a gathering of cranks". However, "one answer to that criticism is that speakers at MCarrison meetings tend to be rather well qualified. But the main point is that the society has a way of asking questions about the environment - what are we doing to it and what it is doing to us - that are of profound importance". The journal "Nutrition and Health" is the official journal of the McCarrison Society and is listed in PUBMED. The journal was started by members in 1978 with the objective of publishing peer reviewed scientific work and reviews on nutrition and health from academic research workers who were independent of the food and agricultural industries or those with a conflict of interest. The Society's website summarises McCarrison's work thus:
His researches were extensive; they included work on the newly discovered
vitamins A vitamin is an organic molecule (or a set of molecules closely related chemically, i.e. vitamers) that is an essential micronutrient that an organism needs in small quantities for the proper functioning of its metabolism. Essential nutrien ...
and on the contrasting disease patterns in the
Indian subcontinent The Indian subcontinent is a list of the physiographic regions of the world, physiographical region in United Nations geoscheme for Asia#Southern Asia, Southern Asia. It is situated on the Indian Plate, projecting southwards into the Indian O ...
. He demonstrated how many common diseases increasingly prevalent in industrial societies were caused simply by diets made defective by extensive food processing, often with the use of chemical additives. He deplored the universal consumption in Britain and America of refined white flour, instead of halite flour, and the substitution of canned, preserved and artificially sweetened products for fresh natural food. McCarrison's work was widely published in the medical press. He was honoured for his discoveries, but completely ignored by government and the medical profession at a time when medical thought was absorbed in the study of disease rather than on prevention and the promotion of health.


Publications

The following is a selection of works published by McCarrison. To avoid duplication, this does not include works cited, which are to be found in the References section. * * * * *
download page
* * * . Retrieved 12 August 2010 * * (Full text at Internet Archive). * (Online registration to view articles is free). * * * * * * * (1945 photo-lithographic reproduction by Lee Foundation for Nutritional Research. Full text at Internet Archive). ** * * (Pay-per-view access). * * * * * * * * . Retrieved 12 August 2010 *
JUSTOR link
* * * * * * * * * * * } * * *


Explanatory notes

a. The bulk of McCarrison's work appears to have been published in the ''
British Medical Journal ''The BMJ'' is a weekly peer-reviewed medical trade journal, published by the trade union the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world's oldest general medical journals. Origi ...
'' (BMJ), although he did publish in other journals, such as ''
JAMA ''The Journal of the American Medical Association'' (''JAMA'') is a peer-reviewed medical journal published 48 times a year by the American Medical Association. It publishes original research, reviews, and editorials covering all aspects of biom ...
'' and ''
The Lancet ''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, ...
'', amongst others. Some publications are also found in the ''
Proceedings of the Royal Society of Medicine The ''Journal of the Royal Society of Medicine'' is a peer-reviewed medical journal. It is the flagship journal of the Royal Society of Medicine with full editorial independence. Its continuous publication history dates back to 1809. Since July 20 ...
''. Free access to publications ''BMJ'' and the ''Proceedings'' is to be found in the external links section. Some of McCarrison's publications listed are from those journals, but links were not located at time of listing. They should however, be available at these websites, along with other publications by or about McCarrison from those two journals which have not been located or listed. b. This letter is by the "nominal overseer" of McCarrison's last salaried post. It contains particularly insightful commentary on the contribution of McCarrison at a time of significant change in the existing university and medical institutions of the UK. c. The author of this obituary letter on McCarrison is identified only as "N.C.P.", which are also the initials of N.C. Penrose, author of a 1951 letter defending the legacy of McCarrison's earlier works. d. A book review of the 1953 edition is cited in this article, hence the listing. However, there have been other publications of this book both before and since. A publication from 1944 (''Nutrition and National Health'') is to be found via web searches comprising the same lecture and essay collection. And publications in 1961 and 1982, under ''Nutrition and Health'', are also to be found. A new edition was produced in 2010, and may found at Lulu, a
Print on Demand Print on demand (POD) is a printing technology and business process in which book copies (or other documents, packaging or materials) are not printed until the company receives an order, allowing prints of single or small quantities. While oth ...
/
Self-Publishing Self-publishing is the publication of media by its author at their own cost, without the involvement of a publisher. The term usually refers to written media, such as books and magazines, either as an ebook or as a physical copy using POD (pr ...
service.


Citations


General and cited references

The following works discuss aspects of the life and work of Robert McCarrison. * * ebook * * * * . Retrieved 11 August 2010. * retrieved 11 August 2010 * * ** * * *


External links


''British Medical Journal'' online archive
Access to articles is free, but requires a simple registration.
RSM journal archives back to 1809 at PubMed Central
Contains archives of the Proceedings of the Royal Society of Medicine, access to which is free
McCarrison Society for Nutrition and Health - homepage
{{DEFAULTSORT:Maccarrison, Robert 1878 births 1960 deaths 20th-century Irish medical doctors 20th-century Irish non-fiction writers British Indian Army generals British nutritionists Companions of the Order of the Indian Empire Diet food advocates Dietitians Fellows of the Royal College of Physicians Indian Army personnel of World War I Indian Medical Service officers Knights Bachelor Medical doctors from Northern Ireland People from Portadown