Robert Cooley Elderfield (May 30, 1904 – December 10, 1979) was an American

chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe th ...

. He was born in

Niagara Falls, New York Niagara Falls is a City (New York), city in Niagara County, New York, United States. As of the 2020 United States Census, 2020 census, the city had a total population of 48,671. It is adjacent to the Niagara River, across from the city of Niagara ...

United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...

. He studied at the

Choate School Choate Rosemary Hall (often known as Choate; ) is a private, co-educational, college-preparatory boarding school in Wallingford, Connecticut, United States. Choate is currently ranked as the second best boarding school and third best private high ...

Wallingford, Connecticut Wallingford is a town in New Haven County, Connecticut, United States, centrally located between New Haven and Hartford, and Boston and New York City. The population was 44,396 at the 2020 census. The community was named after Wallingford, in En ...

, later at the

University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...

receiving his Ph.D. from the

Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the ...

in 1930. He worked at the

Rockefeller Institute of Medical Research The Rockefeller University is a private Private or privates may refer to: Music * " In Private", by Dusty Springfield from the 1990 album ''Reputation'' * Private (band), a Denmark-based band * "Private" (Ryōko Hirosue song), from the 19 ...

from 1930 till 1936 when he changed to

Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...

. He was moved to

in 1952. He started his research with cardiac

glycoside In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. ...

s and cardiac

aglycone An aglycone (aglycon or genin) is the compound remaining after the glycosyl group on a glycoside is replaced by a hydrogen atom. For example, the aglycone of a cardiac glycoside would be a steroid molecule. Detection A way to identify aglycone ...

s shifting to the synthesis of

primaquine Primaquine is a medication used to treat and prevent malaria and to treat ''Pneumocystis'' pneumonia. Specifically it is used for malaria due to ''Plasmodium vivax'' and ''Plasmodium ovale'' along with other medications and for prevention if othe ...

and other

antimalarial Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young c ...

s; at the end he did some research in new anticancer agents

External links

Robert Elderfield's Biographical Memoir from the National Academy of Sciences
1904 births 1979 deaths 20th-century American chemists People from Niagara Falls, New York People from Wallingford, Connecticut University of Michigan alumni University of Michigan faculty Scientists from New York (state) {{US-chemist-stub