Rheumatologic Conditions
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Rheumatism or rheumatic disorders are conditions causing chronic, often intermittent pain affecting the joints or
connective tissue Connective tissue is one of the four primary types of animal tissue, along with epithelial tissue, muscle tissue, and nervous tissue. It develops from the mesenchyme derived from the mesoderm the middle embryonic germ layer. Connective tiss ...
. Rheumatism does not designate any specific disorder, but covers at least 200 different conditions, including
arthritis Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. In som ...
and "non-articular rheumatism", also known as "regional pain syndrome" or "soft tissue rheumatism". There is a close overlap between the term soft tissue disorder and rheumatism. Sometimes the term "soft tissue rheumatic disorders" is used to describe these conditions. The term "Rheumatic Diseases" is used in MeSH to refer to
connective tissue disorders A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds togeth ...
. The branch of medicine devoted to the diagnosis and therapy of rheumatism is called rheumatology.


Types

Many rheumatic disorders of chronic, intermittent
pain Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, ...
(including joint pain, neck pain or back pain) have historically been caused by infectious diseases. Their
etiology Etiology (pronounced ; alternatively: aetiology or ætiology) is the study of causation or origination. The word is derived from the Greek (''aitiología'') "giving a reason for" (, ''aitía'', "cause"); and ('' -logía''). More completely, e ...
was unknown until the 20th century and not treatable. Postinfectious arthritis, also known as reactive arthritis, and
rheumatic fever Rheumatic fever (RF) is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a streptococcal throat infection. Signs and symptoms include fever, multiple painful jo ...
are other examples. In the United States, major rheumatic disorders are divided into 10 major categories based on the nomenclature and classification proposed by the American College of Rheumatology (ACR) in 1983. * Diffuse connective tissue diseases ** Rheumatoid arthritis **
Juvenile arthritis Childhood arthritis (also known as juvenile arthritis, JRA, Juvenile Idiopathic Disease or Arthritis, or Still's Disease) is any form of chronic arthritis or chronic arthritis-related conditions which affects individuals under the age of 16. Most ...
**
Systemic lupus erythematosus Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary among people and may be mild to severe. Comm ...
**
Sjögren syndrome Sjögren syndrome or Sjögren's syndrome (SjS, SS) is a Chronic disease, long-term autoimmune disease that affects the body's moisture-producing (lacrimal and salivary) glands, and often seriously affects other organ systems, such as the lungs, k ...
** Scleroderma ** Polymyositis ** Dermatomyositis ** Behçet's disease ** Relapsing polychondritis * Arthritis associated with spondylitis (i.e. spondarthritis) ** Ankylosing spondylitis ** Reactive arthritis ** Psoriatic arthritis * Osteoarthritis (i.e. osteoarthrosis, degenerative joint disease) * Rheumatic syndromes associated with infectious agents (direct and indirect or reactive) * Metabolic and endocrine diseases associated with rheumatic states ** Gout, pseudogout * Neoplasms * Neurovascular disorders * Bone and cartilage disorders * Extraarticular disorders **
Bursitis Bursitis is the inflammation of one or more bursae (fluid filled sacs) of synovial fluid in the body. They are lined with a synovial membrane that secretes a lubricating synovial fluid. There are more than 150 bursae in the human body. The bursa ...
/ Tendinitis of the shoulder, wrist, biceps, leg, knee cap (patella), ankle, hip, and Achilles tendon **
Capsulitis In anatomy, capsulitis is inflammation of a capsule. Types include: * Adhesive capsulitis of shoulder * Plica syndrome, which is an inflammation of the articular capsule of the knee joint Adhesive capsulitis of shoulder Adhesive capsulitis of ...
* Miscellaneous disorders associated with articular manifestations **
Palindromic rheumatism Palindromic rheumatism (PR) is a syndrome characterised by recurrent, self-resolving inflammatory attacks in and around the joints, consists of arthritis or periarticular soft tissue inflammation. The course is often acute onset, with sudden and r ...
is thought to be a form of rheumatoid arthritis.


Diagnosis

Blood and urine tests will measure levels of creatinine and uric acid to determine kidney function, an elevation of the ESR and CRP is possible. After a purine-restricted diet, another urine test will help determine whether the body is producing too much uric acid or the body isn't excreting enough uric acid.
Rheumatoid factor Rheumatoid factor (RF) is the autoantibody that was first found in rheumatoid arthritis. It is defined as an antibody against the Fc portion of IgG and different RFs can recognize different parts of the IgG-Fc. RF and IgG join to form immune com ...
may be present, especially in the group that is likely to develop rheumatoid arthritis. A fine needle is used to draw fluid from a joint to determine if there is any build up of fluid. The presence of uric acid crystals in the fluid would indicate gout. In many cases there may be no specific test, and it is often a case of eliminating other conditions before getting a correct diagnosis.


Management

Initial therapy of the major rheumatological diseases is with analgesics, such as
paracetamol Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior ...
and non-steroidal anti-inflammatory drugs (NSAIDs). Steroids, especially glucocorticoids, and stronger analgesics are often required for more severe cases.


History

The term ''rheumatism'' stems from the Late Latin ''rheumatismus'', ultimately from Greek ῥευματίζομαι "to suffer from a flux", with '' rheum'' meaning bodily fluids, i.e. any discharge of blood or bodily fluid. Before the 17th century, the joint pain which was thought to be caused by viscous humours seeping into the joints was always referred to as gout, a word adopted in Middle English from Old French ''gote'' "a drop; the gout, rheumatism", not to be confused with the present day specific term referring to excess of uric acid. The English term ''rheumatism'' in the current sense has been in use since the late 17th century, as it was believed that chronic joint pain was caused by excessive flow of '' rheum'' which means bodily fluids into a joint.


See also

* Corbett's electrostatic machine


References


Further reading

*


External links


American College of Rheumatology

National Institute of Arthritis and Musculoskeletal and Skin Diseases
- US National Institute of Arthritis and Musculoskeletal and Skin Diseases {{Authority control Rheumatology Soft tissue disorders