A retrochalcone is a

chalcone Chalcone is the organic compound C6H5C(O)CH=CHC6H5. It is an α,β-unsaturated ketone. A variety of important biological compounds are known collectively as chalcones or chalconoids. Chemical properties Chalcones have two absorption maxima a ...

-like compound in which the normally present hydroxy groups at the 2' and 6' positions are missing. The retrochalcone structure has a propenal bridge connected to two benzene rings at each end. The ring closest to the oxygen, is labelled with primed numbers, normally with a hydroxy group at the 4' position. This is the A ring. The ring closest to the double bond is numbered with simple digits starting from 1 at the bridge connection. This is the B ring. There is usually a hydroxy group at the 4 position. The retrochalcones are found naturally where they are derivatives of flavones. Retrochalcones can be classed as minor flavonoids. One example derivative is echinatin. It has systematic name (E)-1-(4-hydroxyphenol)-3-(3-methoxy-4-hydroxyphenol)-2-propen-1-one, or derived name 4',4-dihydroxy-2-methoxychalcone and was found in ''

Glycyrrhiza echinata ''Glycyrrhiza echinata'' is a species of flowering plant in the genus ''Glycyrrhiza'', with various common names that include Chinese licorice, German licorice, and hedgehog licorice, Eastern European licorice, Hungarian licorice, Prickly licori ...

''.

List

* Licochalcone A (E)-3- -hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl1-(4-hydroxyphenyl)prop-2-en-1-one *Licochalcone B *Licochalcone C *Licochalcone D *Licochalcone E (E)-3- -hydroxy-2-methoxy-5-[(2S)-3-methylbut-3-en-2-ylhenyl">2S)-3-methylbut-3-en-2-yl.html" ;"title="-hydroxy-2-methoxy-5-[(2S)-3-methylbut-3-en-2-yl">-hydroxy-2-methoxy-5-[(2S)-3-methylbut-3-en-2-ylhenyl1-(4-hydroxyphenyl)prop-2-en-1-one *tepanone ((2E)-1-phenyl-3-(2´-hydroxy-3´,4´,6´-trimethoxyphenyl)prop-2-enone

References

{{Reflist Phenyl compounds Chalconoids