Respiratory inductance plethysmography (RIP) is a method of evaluating
pulmonary ventilation by measuring the movement of the chest and abdominal wall.
Accurate measurement of pulmonary ventilation or breathing often requires the use of devices such as masks or mouthpieces coupled to the airway opening. These devices are often both encumbering and invasive, and thus ill suited for continuous or ambulatory measurements. As an alternative RIP devices that sense respiratory excursions at the body surface can be used to measure pulmonary ventilation.
According to a paper by Konno and Mead "the chest can be looked upon as a system of two compartments with only one degree of freedom each". Therefore, any
volume
Volume is a measure of occupied three-dimensional space. It is often quantified numerically using SI derived units (such as the cubic metre and litre) or by various imperial or US customary units (such as the gallon, quart, cubic inch). The de ...
change of the abdomen must be equal and opposite to that of the rib cage. The paper suggests that the volume change is close to being
linearly
Linearity is the property of a mathematical relationship (''function'') that can be graphically represented as a straight line. Linearity is closely related to '' proportionality''. Examples in physics include rectilinear motion, the linear r ...
related to changes in antero-posterior (front to back of body) diameter. When a known air volume is inhaled and measured with a
spirometer
A spirometer is an apparatus for measuring the volume of air inspired and expired by the lungs. A spirometer measures ventilation, the movement of air into and out of the lungs. The spirogram will identify two different types of abnormal ventilat ...
, a volume-motion relationship can be established as the sum of the abdominal and rib cage displacements. Therefore, according to this theory, only changes in the antero-posterior diameter of the abdomen and the rib cage are needed to estimate changes in lung volume.
Several sensor methodologies based on this theory have been developed. RIP is the most frequently used, established and accurate
plethysmography
A plethysmograph is an instrument for measuring changes in volume within an organ or whole body (usually resulting from fluctuations in the amount of blood or air it contains). The word is derived from the Greek "plethysmos" (increasing, enlar ...
method to estimate lung volume from respiratory movements .
RIP has been used in many clinical and academic research studies in a variety of domains including
polysomnographic (sleep), psychophysiology, psychiatric research, anxiety and stress research, anesthesia, cardiology and pulmonary research (asthma, COPD, dyspnea).
Technology
A respiratory inductance plethysmograph consists of two
sinusoid
A sine wave, sinusoidal wave, or just sinusoid is a mathematical curve defined in terms of the ''sine'' trigonometric function, of which it is the graph. It is a type of continuous wave and also a smooth periodic function. It occurs often in ma ...
wire coils insulated and placed within two 2.5 cm (about 1 inch) wide, lightweight elastic and adhesive bands. The
transducer
A transducer is a device that converts energy from one form to another. Usually a transducer converts a signal in one form of energy to a signal in another.
Transducers are often employed at the boundaries of automation, measurement, and contr ...
bands are placed around the rib cage under the armpits and around the abdomen at the level of the
umbilicus (belly button). They are connected to an
oscillator
Oscillation is the repetitive or periodic variation, typically in time, of some measure about a central value (often a point of equilibrium) or between two or more different states. Familiar examples of oscillation include a swinging pendulum ...
and subsequent frequency
demodulation
Demodulation is extracting the original information-bearing signal from a carrier wave. A demodulator is an electronic circuit (or computer program in a software-defined radio) that is used to recover the information content from the modulated ...
electronics to obtain digital waveforms. During inspiration the cross-sectional area of the rib cage and abdomen increases altering the self-inductance of the coils and the frequency of their oscillation, with the increase in cross-sectional area proportional to lung volumes. The electronics convert this change in frequency to a digital respiration waveform where the amplitude of the waveform is proportional to the inspired breath volume. A typical pitch of the wire sinusoid is in the range 1-2 cm and the inductance of the belt is ~ 2-4 microhenries per metre of belt. The inductance can be measured by making it part of the
tuned circuit
An LC circuit, also called a resonant circuit, tank circuit, or tuned circuit, is an electric circuit consisting of an inductor, represented by the letter L, and a capacitor, represented by the letter C, connected together. The circuit can ac ...
of an oscillator and then measuring the oscillation frequency.
Single Vs. Dual Band Respiration
Dual Band Respiration
Konno and Mead extensively evaluated a two-degrees-of-freedom model of chest wall motion, whereby ventilation could be derived from measurements of rib cage and abdomen displacements. With this model,
tidal volume
Tidal volume (symbol VT or TV) is the volume of air moved into or out of the lungs during a normal breath. In a healthy, young human adult, tidal volume is approximately 500 ml per inspiration or 7 ml/kg of body mass.
Mechanical vent ...
(Vt) was calculated as the sum of the anteroposterior dimensions of the rib cage and abdomen, and could be measured to within 10% of actual Vt as long as a given posture was maintained.
Single Band Respiration
Changes in volume of the thoracic cavity can also be inferred from displacements of the rib cage and
diaphragm. Motion of the rib cage can be directly assessed, whereas the motion of the diaphragm is indirectly assessed as the outward movement of the anterolateral abdominal wall.
However, accuracy issues arise when trying to assess accurate respiratory volumes from a single respiration band placed either at the thorax, abdomen or midline. Due to differences in posture and thoraco-abdominal respiratory synchronization it is not possible to obtain accurate respiratory volumes with a single band. Furthermore, the shape of the acquired waveform tends to be non-linear due to the non-exact co-ordination of the two respiratory compartments. This further limits quantification of many useful respiratory indices and limits utility to only respiration rates and other basic timing indices. Therefore, to accurately perform volumetric respiratory measurements, a dual band respiratory sensor system must be required.
RIP Data Analysis
![VivoSenseRIP](https://upload.wikimedia.org/wikipedia/commons/9/92/VivoSenseRIP.jpg)
]
Dual band respiratory inductance plethysmography can be used to describe various measures of complex respiratory patterns. The image shows waveforms and measures commonly analyzed.
''Respiratory rate'' is the number of breaths per minute. A non-specific measure of respiratory disorder.
''Tidal volume (Vt)'' is the volume inspired and expired with each breath. Variability in the wave form can be used to differentiate between restrictive (less) and obstructive pulmonary diseases as well as acute anxiety.
''Minute ventilation'' is equivalent to tidal volume multiplied by respiratory rate and is used to assess metabolic activity.
''Peak inspiratory flow (PifVt)'' is a measure that reflects respiratory drive, the higher its value, the greater the respiratory drive in the presence of coordinated thoraco-abdominal or even moderately discoordinated thoraco-abdominal movements.
''Fractional inspiratory time (Ti/Tt) '' is the "Duty cycle" (Ti/Tt, ratio of time of inspirationy to total breath time). Low values may reflect
severe airways obstruction and can also occur during speech. Higher values are observed when snoring.
''Work of breathing '' is a measure of a "Rapid shallow breathing index".
''Peak/mean inspiratory and expiratory flow'' measures the presence of upper airway flow limitations during inspiration and expiration.
''%RCi'' is the percent contribution of the rib cage excursions to the tidal volume Vt. The %RCi contribution to Tidal Volume ratio is obtained by dividing the inspired volume in the RC band by the inspired volume in the algebraic sum of RC + AB at the point of the peak of inspiratory tidal volume. This value is higher in woman than in men. The values are also generally higher during acute
hyperventilation
Hyperventilation is irregular breathing that occurs when the rate or tidal volume of breathing eliminates more carbon dioxide than the body can produce. This leads to hypocapnia, a reduced concentration of carbon dioxide dissolved in the blood. ...
.
''Phase Angle - Phi'' - Normal breathing involves a combination of both thoracic and abdominal (diaphragmatic) movements. During inhalation, both the thoracic and abdominal cavities simultaneously expand in volume, and thus in girth as well. If there is a blockage in the trachea or nasopharynx, the phasing of these movements will shift in relation to the degree of the obstruction. In the case of a total obstruction, the strong chest muscles force the thorax to expand, pulling the diaphragm upward in what is referred to as "paradoxical" breathing – paradoxical in that the normal phases of thoracic and abdominal motion are reversed. This is commonly referred to as the Phase Angle.
''
Apnea
Apnea, BrE: apnoea, is the temporal cessation of breathing. During apnea, there is no movement of the muscles of inhalation, and the volume of the lungs initially remains unchanged. Depending on how blocked the airways are ( patency), there ...
&
hypopnea
Hypopnea is overly shallow breathing or an abnormally low respiratory rate. Hypopnea is defined by some to be less severe than apnea (the complete cessation of breathing), while other researchers have discovered hypopnea to have a "similar if n ...
detection'' - Diagnostic components of sleep apnea/hypopnea syndrome and periodic breathing.
''Apnea & hypopnea classification'' - Phase relation between thorax and abdomen classifies apnea/hypopnea events into central, mixed, and obstructive types.
''qDEEL quantitative difference of end expiratory lung volume'' is a change in the level of end expiratory lung volume and may be elevated in
Cheyne-Stokes respiration and periodic breathing.
Accuracy
Dual band respiratory inductance plethysmography was validated in determining tidal volume during exercise and shown to be accurate. A version of RIP embedded in a garment called the LifeShirt was used for these validation studies.
References
{{Reflist
External links
Use of RIP for preclinical research in freely moving animals :
emkaPACK4G Jacketed External Telemetry(large animals)
Jacketed External Telemetry JETlarge animals)
DECROsmall animals)
Biotechnology
Biomedicine