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René Joseph Quinton (1866–1925) was a French biologist, aviation pioneer and decorated World War I soldier. In his biology career, he developed a treatment based on seawater injections that he called ''sérum de Quinton'', which has been abandoned by medicine. An aviation pioneer, he was vice-president of the ''Ligue Aéronautique de France'' and a proponent of the development of aviation in France. During World War I, he rose through the ranks to end the war as ''Commandeur de la Légion d'honneur'', with multiple awards and decorations from France and Allies.


Early life

Quinton was born on 15 December 1866, in Chaumes-en-Brie (Seine-et-Marne) France. His father, Paul Edouart Quinton was a medical doctor. His mother, Marie Pauline Elisabeth Amyot, had no profession. He attended secondary school at the ''Collège Chaptal'', in
Paris Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. S ...
. As a young adult, Quinton was interested in literature; he read and wrote poetry and started writing a novel. He was influenced by
Flaubert Gustave Flaubert ( , , ; 12 December 1821 – 8 May 1880) was a French novelist. Highly influential, he has been considered the leading exponent of literary realism in his country. According to the literary theorist Kornelije Kvas, "in Flauber ...
’s work and his writing endeavors were described as perfectionist and meticulous by his friends. According to his friend Armand Charpentier, Quinton’s wealthy situation allowed him to spend a lot of time in the pursuit of writing perfection, but after 10 years of writing, and not completing any project, his interests turned to biology. He decided to enter the ''
Collège de France The Collège de France (), formerly known as the ''Collège Royal'' or as the ''Collège impérial'' founded in 1530 by François I, is a higher education and research establishment (''grand établissement'') in France. It is located in Paris ne ...
'' as an assistant at the ''Laboratoire de Physiologie pathologique''. His passion lay in the study of the origins of life: for Quinton, the sea was the matrix of life, a theory on which he would base the remainder of his career in biology. Quinton also had an interest in aviation. At the ''Collège de France'', he met French physiologist
Étienne-Jules Marey Étienne-Jules Marey (; 5 March 1830, Beaune, Côte-d'Or – 15 May 1904, Paris) was a French scientist, physiologist and chronophotographer. His work was significant in the development of cardiology, physical instrumentation, aviation, cinema ...
, who was working on the study of flight, and rapidly became his disciple and friend.


Biology

Quinton’s interest in the origins of life and seawater as the matrix of life led him to theorize his ''Loi de constance'' and to create ''sérum de Quinton''.


Loi de Constance

Quinton posited a ''Loi de constance'' (Law of constancy) that opposed, on some points,
Darwin's theory of evolution Darwinism is a theory of biological evolution developed by the English naturalist Charles Darwin (1809–1882) and others, stating that all species of organisms arise and develop through the natural selection of small, inherited variations that ...
. In his ''Loi de constance'', he hypothesized that nature repeats rather than evolves. In this ''Loi'', Quinton included the following sub categories: ''constance marine'' (marine constancy), ''constance osmotique'' (osmotic constancy) and ''constance thermique'' (thermal constancy). He reported his findings in the only book he would ever publish: ''L’eau de mer, milieu organique'', in 1904. The publication provoked disagreements and was met with resistance, nonetheless, it was the basis for therapeutic applications that Quinton would begin in the following years. Today, Quinton’s book is published as part of the French cultural heritage, but its content is considered antiquated and the views it describes not valid.


Sérum de Quinton

Quinton’s theories led him to conclude “that Seawater is the "vital liquid" of all living beings and the means of curing all kinds of disease”. He imagined subcutaneous seawater injections as a therapeutic treatment. In 1907, Quinton patented the ''sérum de Quinton'' (Quinton serum). He described it as seawater harvested from the Atlantic, in specific areas where he considered the water “pure” and with special precautions. The harvest was then immediately transported to Paris where it was sterilized without boiling or chemical products, brought to a specific saline concentration, and stored in vials. With this patented technique, the serum was comparable, according to Quinton, to blood. As such, it could be used to treat the following conditions:
enteritis Enteritis is inflammation of the small intestine. It is most commonly caused by food or drink contaminated with pathogenic microbes,Dugdale, David C., IIII, and George F Longretc"Enteritis" MedlinePlus Medical Encyclopedia, 18 October 2008. Access ...
, constipation, diarrhea,
colitis Colitis is swelling or inflammation of the large intestine ( colon). Colitis may be acute and self-limited or long-term. It broadly fits into the category of digestive diseases. In a medical context, the label ''colitis'' (without qualification) ...
, newborn
gastroenteritis Gastroenteritis, also known as infectious diarrhea and gastro, is an inflammation of the gastrointestinal tract including the stomach and intestine. Symptoms may include diarrhea, vomiting, and abdominal pain. Fever, lack of energy, and dehydra ...
, lactose intolerance, athrepsia, and skin conditions. It was also presented as a prenatal treatment to prevent the future baby(ies) from developing
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
,
syphilis Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, an ...
or
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
, and to help expecting mothers with nausea. He proceeded to open and fund Parisian dispensaries, reserved for destitute patients, to treat, at no charge, these conditions. These treatments were reported, at the time, to be very successful and with no side effects. However, they have since been abandoned by medicine and removed from the Vidal dictionary, the French dictionary that catalogs medications and dietary supplements. Today, Quinton serum continues to be sold by Quinton Laboratory as personal and hygiene products, not medicine, in the form of drinkable vials or nasal sprays.


The dog experiments

Some experiments of René Quinton, to support his theory that seawater can be used as a substitute for blood, are the dog experiments. In his 1897 experiments, Quinton reported the following. He removed the totality of a dog’s blood and replaced it with sterilized seawater. The dog developed an infection and fever, but went on to recuperate within 5 days, and was still alive 5 years later. Quinton concluded that his purified seawater formula could be used as a substitute for blood transfusion. Harriett Hall challenges the study: “There is a huge body of established scientific knowledge that would have to be overthrown before we could accept that an animal’s entire blood volume could be replaced with saline without resulting in death. Extraordinary claims require extraordinary evidence, and this century-old report doesn’t even meet the standards of ordinary peer-reviewed published evidence.”


Aviation

Another area of interest for René Quinton was aviation. In 1908, inspired by other countries offering rewards to creators of
aircraft An aircraft is a vehicle that is able to fly by gaining support from the air. It counters the force of gravity by using either static lift or by using the dynamic lift of an airfoil, or in a few cases the downward thrust from jet engines ...
, as well as France’s success in
ballooning Ballooning may refer to: * Hot air ballooning * Balloon (aeronautics) * Ballooning (spider) * Ballooning degeneration, a disease * Memory ballooning See also * Balloon (disambiguation) A balloon is a flexible container for (partially or fully) co ...
, René Quinton, along with
Archdeacon An archdeacon is a senior clergy position in the Church of the East, Chaldean Catholic Church, Syriac Orthodox Church, Anglican Communion, St Thomas Christians, Eastern Orthodox churches and some other Christian denominations, above that o ...
and others, founded the ''Ligue Nationale Aérienne'', of which he was president. His goal was to set up a yearly subscription that would generate enough money to offer a prize to the first French creator to invent an ideal aircraft. The league’s role was to encourage and promote enthusiasm for aviation, with the hope that France would become a leader in the field. Quinton also lobbied for the development of aircraft as an important way to spot injured soldiers and bring them to safety for care. Quinton was president of the league for 4 years after which he left for the war. When he returned, Quinton drew back from this project, focusing on ''sérum de Quinton'' instead. He facilitated the fusion of his league with ''l’Association Genérale Aéronautique'' and the ''Comité National de l’Aviation Militaire''; these 3 societies combined to form the Ligue Aéronautique de France, with General Bailly as president, and Reymond and Quinton as Vice-presidents. A meeting took place in
Biskra Biskra ( ar, بسكرة ; ; Latin Vescera) is the capital city of Biskra Province, Algeria. In 2007, its population was recorded as 307,987. Biskra is located in northeastern Algeria, about 248 miles (400 km) from Algiers, 71 miles (115&nbs ...
, where several aviators presented their creations. A second meeting was planned, but Quinton died unexpectedly before then.


World War I

When
World War I World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...
broke out, Quinton was not required to go to combat due to his age. Nonetheless, according to Georges Houard, Quinton's strong patriotism and love of France compelled him to go to war. At the beginning of the war, in 1914, he fought as ''capitaine d'artillerie de réserve''. Throughout the war, his fellows and superiors described him as brave, composed and eager;
Foch Ferdinand Foch ( , ; 2 October 1851 – 20 March 1929) was a French general and military theorist who served as the Supreme Allied Commander during the First World War. An aggressive, even reckless commander at the First Marne, Flanders and Ar ...
wrote the following about Quinton: “Officer of the rarest intrepidity, for whom it is impossible to resume the acts of bravery. Continues to show the best example of composure, energy and drive.” He rose through the ranks to end the war as ''Commandeur de la
Légion d'honneur The National Order of the Legion of Honour (french: Ordre national de la Légion d'honneur), formerly the Royal Order of the Legion of Honour ('), is the highest French order of merit, both military and civil. Established in 1802 by Napoleon ...
'', with multiple decorations.


Battlefronts

René Quinton fought on the following battlefronts during World War I:


Injuries

During the war, Quinton suffered 8 injuries, including receiving a
shrapnel Shrapnel may refer to: Military * Shrapnel shell, explosive artillery munitions, generally for anti-personnel use * Shrapnel (fragment), a hard loose material Popular culture * ''Shrapnel'' (Radical Comics) * ''Shrapnel'', a game by Adam C ...
to the nape, multiple head and face contusions, and injuries and
frostbite Frostbite is a skin injury that occurs when exposed to extreme low temperatures, causing the freezing of the skin or other tissues, commonly affecting the fingers, toes, nose, ears, cheeks and chin areas. Most often, frostbite occurs in the han ...
to the feet.


Military titles and awards

For his war efforts, René Quinton received the following titles and awards from the French military: * ''Chevalier de la Légion d'honneur, on 20 July 1916'' * ''Officier de la Légion d'honneur, on 10 July 1917'' * ''Commandeur de la Légion d'honneur'', on 16 June 1920 * ''
Croix de guerre The ''Croix de Guerre'' (, ''Cross of War'') is a military decoration of France. It was first created in 1915 and consists of a square-cross medal on two crossed swords, hanging from a ribbon with various degree pins. The decoration was first awa ...
'', 5 Palms and 2 Stars Quinton was also recognized in Allied countries. On 26 November 1914, he was named ''Chevalier de l' Ordre de Léopold'' in
Belgium Belgium, ; french: Belgique ; german: Belgien officially the Kingdom of Belgium, is a country in Northwestern Europe. The country is bordered by the Netherlands to the north, Germany to the east, Luxembourg to the southeast, France to th ...
, and in 1916 he received the ''
Croix de guerre The ''Croix de Guerre'' (, ''Cross of War'') is a military decoration of France. It was first created in 1915 and consists of a square-cross medal on two crossed swords, hanging from a ribbon with various degree pins. The decoration was first awa ...
'' from Belgium too. He received the
Distinguished Service Cross The Distinguished Service Cross (D.S.C.) is a military decoration for courage. Different versions exist for different countries. *Distinguished Service Cross (Australia) The Distinguished Service Cross (DSC) is a military decoration awarded to ...
from the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and North ...
on 27 August 1917 and on 5 March 1919 from the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
.


Death

Quinton passed away unexpectedly on 9 July 1925, from a sudden onset heart condition; he was 58 years old. On his deathbed, he identified as a soldier: he told his comrades, while saying his final goodbyes, “and that is why I insisted to die in my soldier’s garments”. He was with his cousin Lucien Corpechot when he passed. He was buried in his family vault in Loches-sur-Ource (Aube). A statue commemorating Quinton was erected in his birth town of Chaumes-en-Brie in 1931. It featured a bronze statue sculpted by Paul Dardé. However, in 1941, the statue was removed and melted by the German army. Today, only the base of the statue remains and can be seen in its original location in the Champ de foire of Chaumes-en-Brie.


Bibliography

During his lifetime, Quinton published his findings in biology in the following book, which is currently published as a historical heritage book, as the contents are considered out of date: ''L'eau de mer milieu organique: constance du milieu marin originel, comme milieu vital des cellules'' (1904). Some of his written words were also compiled in the following book about war: ''Maximes sur la guerre'' (1930).


References

{{DEFAULTSORT:Quinton, Rene 1925 deaths 1866 births 19th-century French scientists Commandeurs of the Légion d'honneur