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René-Théophile-Hyacinthe Laennec (; 17 February 1781 – 13 August 1826) was a French
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
and
musician A musician is a person who composes, conducts, or performs music. According to the United States Employment Service, "musician" is a general term used to designate one who follows music as a profession. Musicians include songwriters who wri ...
. His skill at carving his own wooden flutes led him to invent the
stethoscope The stethoscope is a medical device for auscultation, or listening to internal sounds of an animal or human body. It typically has a small disc-shaped resonator that is placed against the skin, and one or two tubes connected to two earpieces. ...
in 1816, while working at the Hôpital Necker. He pioneered its use in diagnosing various
chest The thorax or chest is a part of the anatomy of humans, mammals, and other tetrapod animals located between the neck and the abdomen. In insects, crustaceans, and the extinct trilobites, the thorax is one of the three main divisions of the crea ...
conditions. He became a lecturer at the
Collège de France The Collège de France (), formerly known as the ''Collège Royal'' or as the ''Collège impérial'' founded in 1530 by François I, is a higher education and research establishment (''grand établissement'') in France. It is located in Paris ne ...
in 1822 and professor of medicine in 1823. His final appointments were that of head of the medical clinic at the
Hôpital de la Charité Hôpital de la Charité (, "Charity Hospital") was a hospital in Paris founded in the 17th century and closed in 1935. History In 1606, Marie de Médicis invited the Brothers Hospitallers of St. John of God to come to France. The Abbot of Sain ...
and
professor Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who pr ...
at the Collège de France. He went into a coma and subsequently died of
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
on August 13, 1826 at age 45.


Early life

Laennec was born in
Quimper Quimper (, ; br, Kemper ; la, Civitas Aquilonia or ) is a commune and prefecture of the Finistère department of Brittany in northwestern France. Administration Quimper is the prefecture (capital) of the Finistère department. Geography The ...
(
Brittany Brittany (; french: link=no, Bretagne ; br, Breizh, or ; Gallo language, Gallo: ''Bertaèyn'' ) is a peninsula, Historical region, historical country and cultural area in the west of modern France, covering the western part of what was known ...
). His mother died of tuberculosis when he was five years old, and he went to live with his great-uncle the
Abbé ''Abbé'' (from Latin ''abbas'', in turn from Greek , ''abbas'', from Aramaic ''abba'', a title of honour, literally meaning "the father, my father", emphatic state of ''abh'', "father") is the French word for an abbot. It is the title for lowe ...
Laennec (a priest). As a child, Laennec became ill with
lassitude Fatigue describes a state of tiredness that does not resolve with rest or sleep. In general usage, fatigue is synonymous with extreme tiredness or exhaustion that normally follows prolonged physical or mental activity. When it does not resolve ...
and repeated instances of
pyrexia Fever, also referred to as pyrexia, is defined as having a temperature above the normal range due to an increase in the body's temperature set point. There is not a single agreed-upon upper limit for normal temperature with sources using val ...
. Laennec was also thought to have
asthma Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, cou ...
. At the age of twelve, he proceeded to
Nantes Nantes (, , ; Gallo: or ; ) is a city in Loire-Atlantique on the Loire, from the Atlantic coast. The city is the sixth largest in France, with a population of 314,138 in Nantes proper and a metropolitan area of nearly 1 million inhabita ...
, where his uncle, Guillaime-François Laennec, worked in the faculty of medicine at the university. Laennec was a gifted student. His father (a lawyer) later discouraged him from continuing as a doctor and René then had a period of time where he took long walks in the country, danced, studied Greek, and wrote poetry. However, in 1799 he returned to study. Laennec studied medicine at the
University of Paris , image_name = Coat of arms of the University of Paris.svg , image_size = 150px , caption = Coat of Arms , latin_name = Universitas magistrorum et scholarium Parisiensis , motto = ''Hic et ubique terrarum'' (Latin) , mottoeng = Here and a ...
under several famous physicians, including
Dupuytren Baron Guillaume Dupuytren (; 5 October 1777 – 8 February 1835) was a French anatomist and military surgeon. Although he gained much esteem for treating Napoleon Bonaparte's hemorrhoids, he is best known today for his description of Dupuytren' ...
and Jean-Nicolas Corvisart-Desmarets. There he was trained to use sound as a diagnostic aid. Corvisart advocated the re-introduction of
percussion A percussion instrument is a musical instrument that is sounded by being struck or scraped by a beater including attached or enclosed beaters or rattles struck, scraped or rubbed by hand or struck against another similar instrument. Exc ...
during the
French Revolution The French Revolution ( ) was a period of radical political and societal change in France that began with the Estates General of 1789 and ended with the formation of the French Consulate in November 1799. Many of its ideas are considere ...
.


Invention of the stethoscope

René Laennec wrote in the classic treatise ''De l'Auscultation Médiate'',
In 1816,
e was E, or e, is the fifth letter and the second vowel letter in the Latin alphabet, used in the modern English alphabet, the alphabets of other western European languages and others worldwide. Its name in English is ''e'' (pronounced ); plu ...
consulted by a young woman laboring under general symptoms of diseased heart, and in whose case percussion and the application of the hand were of little avail on account of the great degree of fatness. The other method just mentioned direct
auscultation Auscultation (based on the Latin verb ''auscultare'' "to listen") is listening to the internal sounds of the body, usually using a stethoscope. Auscultation is performed for the purposes of examining the circulatory and respiratory systems (hea ...
being rendered inadmissible by the age and sex of the patient, I happened to recollect a simple and well-known fact in acoustics, ... the great distinctness with which we hear the scratch of a pin at one end of a piece of wood on applying our ear to the other. Immediately, on this suggestion, I rolled a quire of paper into a kind of cylinder and applied one end of it to the region of the heart and the other to my ear, and was not a little surprised and pleased to find that I could thereby perceive the action of the heart in a manner much more clear and distinct than I had ever been able to do by the immediate application of my ear.
Laennec had discovered that the new
stethoscope The stethoscope is a medical device for auscultation, or listening to internal sounds of an animal or human body. It typically has a small disc-shaped resonator that is placed against the skin, and one or two tubes connected to two earpieces. ...
was superior to the normally used method of placing the ear over the chest, particularly if the patient was overweight. A stethoscope also avoided the embarrassment of placing the ear against the chest of a woman. Laennec is said to have seen schoolchildren playing with long, hollow sticks in the days leading up to his innovation. The children held their ear to one end of the stick while the opposite end was scratched with a pin, the stick transmitted and amplified the scratch. His skill as a flautist may also have inspired him. He built his first instrument as a 25 cm by 2.5 cm hollow wooden cylinder, which he later refined into three detachable parts. The refined design featured a funnel-shaped cavity to augment the sound, separable from the body of the stethoscope. His clinical work allowed him to follow chest patients from bedside to the autopsy table. He was therefore able to correlate sounds captured by his new instruments with specific pathological changes in the chest, in effect pioneering a new non-invasive diagnostic tool. Pulmonary phthisis, for example, was one ailment he could more clearly identify using his knowledge of typical and atypical chest sounds. Laennec was the first to classify and discuss the terms
rales Crackles are the clicking, rattling, or crackling noises that may be made by one or both lungs of a human with a respiratory disease during inhalation. They are usually heard only with a stethoscope ("on auscultation"). Pulmonary crackles are a ...
,
rhonchi Respiratory sounds, also known as lung sounds or breath sounds, refer to the specific sounds generated by the movement of air through the respiratory system. These may be easily audible or identified through auscultation of the respiratory system ...
,
crepitance Crackles are the clicking noise, clicking, rattling, or crackling noises that may be made by one or both lungs of a human with a respiratory disease during inhalation. They are usually heard only with a stethoscope ("on auscultation"). Pulmonary ...
, and
egophony Egophony (British English, aegophony) is an increased resonance of voice sounds heard when auscultating the lungs, often caused by lung consolidation and fibrosis. It is due to enhanced transmission of high-frequency sound across fluid, such as in ...
– terms that doctors now use on a daily basis during physical exams and diagnoses. Laënnec presented his findings and research on the stethoscope to the
French Academy of Sciences The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV of France, Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French Scientific me ...
, and in 1819 he published his masterpiece ''On Mediate Auscultation''. Two volumes. Laennec coined the phrase ''mediate
auscultation Auscultation (based on the Latin verb ''auscultare'' "to listen") is listening to the internal sounds of the body, usually using a stethoscope. Auscultation is performed for the purposes of examining the circulatory and respiratory systems (hea ...
'' (indirect listening), as opposed to the popular practice at the time of directly placing the ear on the chest ( immediate auscultation). He named his instrument the
stethoscope The stethoscope is a medical device for auscultation, or listening to internal sounds of an animal or human body. It typically has a small disc-shaped resonator that is placed against the skin, and one or two tubes connected to two earpieces. ...
, from the Greek words '' tethos' (chest), and '' kopos' (examination). The stethoscope quickly gained popularity as ''De l'Auscultation Médiate'' was translated and distributed across France, England, Italy, and Germany in the early 1820s. However, not all doctors readily embraced the new stethoscope. Although the ''
New England Journal of Medicine ''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. It is among the most prestigious peer-reviewed medical journals as well as the oldest continuously published one. Hist ...
'' reported the invention of the stethoscope two years later in 1821, as late as 1885, a professor of medicine stated, "He that hath ears to hear, let him use his ears and not a stethoscope." Even the founder of the
American Heart Association The American Heart Association (AHA) is a nonprofit organization in the United States that funds cardiovascular medical research, educates consumers on healthy living and fosters appropriate cardiac care in an effort to reduce disability and death ...
, L.A. Connor (1866–1950), carried a silk handkerchief with him to place on the wall of the chest for ear auscultation. Laennec often referred to the stethoscope as "the cylinder", and as he neared death only a few years later, he bequeathed his own stethoscope to his nephew, referring to it as "the greatest legacy of my life". The modern type, with two earpieces, was invented in 1851 by A. Leared; in 1852 G.P. Cammann perfected the design of the instrument for commercial production, which has become the current standard form.


Other medical contributions

He developed the understanding of
peritonitis Peritonitis is inflammation of the localized or generalized peritoneum, the lining of the inner wall of the abdomen and cover of the abdominal organs. Symptoms may include severe pain, swelling of the abdomen, fever, or weight loss. One part or ...
and
cirrhosis Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is the impaired liver function caused by the formation of scar tissue known as fibrosis due to damage caused by liver disease. Damage causes tissue repai ...
. Although the disease of cirrhosis was known, Laennec gave cirrhosis its name, using the Greek word ( ''kirrhos'', tawny) that referred to the tawny, yellow nodules characteristic of the disease. He coined the term ''
melanoma Melanoma, also redundantly known as malignant melanoma, is a type of skin cancer that develops from the pigment-producing cells known as melanocytes. Melanomas typically occur in the skin, but may rarely occur in the mouth, intestines, or eye ( ...
'' and described ''
metastases Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, ...
'' of melanoma to the lungs. In 1804, while still a medical student, he was the first person to lecture on melanoma. This lecture was subsequently published in 1805. Laennec actually used the term ''melanose'', which he derived from the Greek (, ''melan'', ''mela'') for "black". Over the years, there were bitter exchanges between Laennec and
Dupuytren Baron Guillaume Dupuytren (; 5 October 1777 – 8 February 1835) was a French anatomist and military surgeon. Although he gained much esteem for treating Napoleon Bonaparte's hemorrhoids, he is best known today for his description of Dupuytren' ...
, the latter objecting that there was no mention of his work in this area and his role in its discovery. He also studied
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
. Coincidentally, his nephew, Mériadec Laennec, is said to have diagnosed tuberculosis in Laennec using Laennec's stethoscope. Laennec wrote ''A Treatise on the Disease of the Chest'', in which he focused on diseases of the chest such as ''
phthisis pulmonalis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
'' (tuberculosis) and diagnostics such as ''
pectoriloquy Pectoriloquy is the increased resonance of the voice through the lung structures, so that it is clearly comprehensible using a stethoscope on the chest. It usually indicates consolidation of the underlying lung parenchyma. Types include egophony ...
''. He discussed the symptoms of Phthisis pulmonalis and what parts of the body it affects. It was written in an academic manner for learning purposes. Laennec advocated objective scientific observation. Professor Benjamin Ward Richardson stated in ''Disciples of Aesculapius'' that "the true student of medicine reads Laennec's treatise on mediate auscultation and the use of the stethoscope once in two years at least as long as he is in practice. It ranks with the original work of
Vesalius Andreas Vesalius (Latinized from Andries van Wezel) () was a 16th-century anatomist, physician, and author of one of the most influential books on human anatomy, ''De Humani Corporis Fabrica Libri Septem'' (''On the fabric of the human body'' '' ...
,
Harvey Harvey, Harveys or Harvey's may refer to: Arts, entertainment, and media * ''Harvey'' (play), a 1944 play by Mary Chase about a man befriended by an invisible anthropomorphic rabbit * Harvey Awards ("Harveys"), one of the most important awards ...
and
Hippocrates Hippocrates of Kos (; grc-gre, Ἱπποκράτης ὁ Κῷος, Hippokrátēs ho Kôios; ), also known as Hippocrates II, was a Greek physician of the classical period who is considered one of the most outstanding figures in the history of ...
."


Religious views

Laennec "was intensely religious and was a devout Catholic all his life". He was noted as a very kind man and his charity to the poor became proverbial.
Austin Flint Austin Flint I (October 20, 1812 – March 13, 1886) was an American physician. He was a founder of Buffalo Medical College, precursor to The State University of New York at Buffalo. He served as president of the American Medical Association. ...
, the 1884 president of the
American Medical Association The American Medical Association (AMA) is a professional association and lobbying group of physicians and medical students. Founded in 1847, it is headquartered in Chicago, Illinois. Membership was approximately 240,000 in 2016. The AMA's state ...
, said that "Laennec's life affords a striking instance among others disproving the vulgar error that the pursuit of science is unfavourable to religious faith." In J. Forbes' annotated translation of Laennec's treatise, Forbes reported:


Legacy and tribute

Medical terms named after Laennec: *
Laennec's cirrhosis Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is the impaired liver function caused by the formation of scar tissue known as fibrosis due to damage caused by liver disease. Damage causes tissue repai ...
refers to the appearance of regenerated liver, comprising small lobules separated by a fine, fibrous tissue; * Laennec's thrombus is an antenatal thrombus in the heart; * Laennec's pearls refer to sputum produced by asthmatics; * ''Hamman's murmur'', also known as ''Laënnec–Hamman symptom'', ''Laënnec–Müller–von Bergmann–Hamman symptom'', or ''Hamman's crunch'', is a crunching sound due to spontaneous mediastinal emphysema, heard over the precordium. Honors: * At the
Université Claude Bernard Lyon 1 Claude Bernard University Lyon 1 (french: link=no, Université Claude-Bernard Lyon 1, UCBL) is one of the three public universities of Lyon, France. It is named after the French physiologist Claude Bernard and specialises in science and technolo ...
one of the four medical schools is named after Laennec. * On 17 February 2016,
Google Google LLC () is an American multinational technology company focusing on search engine technology, online advertising, cloud computing, computer software, quantum computing, e-commerce, artificial intelligence, and consumer electronics. ...
celebrated his 235th birthday with a
Google Doodle A Google Doodle is a special, temporary alteration of the logo on Google's homepages intended to commemorate holidays, events, achievements, and notable historical figures. The first Google Doodle honored the 1998 edition of the long-running an ...
.


Laennec in fiction

A Rene Laennec appears in Rudyard Kipling's ''
Rewards and Fairies ''Rewards and Fairies'' is a historical fantasy book by Rudyard Kipling published in 1910. The title comes from the poem "Farewell, Rewards and Fairies" by Richard Corbet, which was referred to by the children in the first story of Kipling's ...
'', the second of two books where two children, Dan and Una, encounter past inhabitants of England. In the short section "Marlake Witches", set during the Napoleonic Wars, Una meets a consumptive young lady who speaks of being treated by a French doctor, a prisoner on parole, one Rene Laennec. This prisoner discusses with a local herbalist the use of 'wooden trumpets' for listening to patients' chests, much to the distrust of the local doctor. Obviously, Kipling was aware of Laennec's work and invented an English connection. He was the subject of a 1949 French film '' Doctor Laennec'' in which he was played by
Pierre Blanchar Pierre Blanchar (30 June 1892 – 21 November 1963) was a French actor. He appeared in more than 50 films between 1922 and 1961. Blanchar was married to actress Marthe Vinot, with whom he had a daughter, actress Dominique Blanchar. He playe ...
.


Laennec's landmarks in Paris

On the exterior wall of the " Hôpital Necker – Enfants Malades", where Laennec wrote ''Mediate auscultation'', near the entrance of the hospital in 149, Rue de Sèvres, there is a marble memorial tablet with an engraved portrait of Laennec and this inscription: "Dans cet hôpital Laennec découvrit l'auscultation. 1781–1826". Some of the oldest buildings of the hospital can be seen on the same front of this large and modern medical area. Image:Laennec memorial, Necker Hospital, Paris 1.jpg, The entrance in Rue de Sèvres Image:Hopital_Necker_Laennec_stethoscope_2.jpg, Laennec's memorial tablet Image:Laennec memorial, Necker Hospital, Paris 3.jpg, One of the old buildings of the hospital Image:Rene-Theophile-Hyacinthe Laennec (1781-1826) thesis title page.jpg , De l'auscultation médiate ... Paris: J.-A. Brosson et J.-S. Chaude, 1819. Image:Rene-Theophile-Hyacinthe Laennec (1781-1826) Drawings stethoscope and lungs.jpg , ''De l'auscultation médiate ...''. Drawings of the stethoscope and lungs. Image:Rene-Theophile-Hyacinthe Laennec (1781-1826) Drawings diseased lungs.jpg , ''De l'auscultation médiate ...'' Most of the plates in his book illustrate the diseased lung as do these four images that are consistent with lungs affected by
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
.


Footnotes


References


Further reading

* * * — ''The complete title of this book, often referred to as the'' 'Treatise' ''is'' De l'Auscultation Médiate ou Traité du Diagnostic des Maladies des Poumons et du Coeur (''On Mediate Auscultation or Treatise on the Diagnosis of the Diseases of the Lungs and Heart''). * – lick 'à télécharger' for the English version/small>. * {{DEFAULTSORT:Laennec, Rene 1781 births 1826 deaths People from Quimper 19th-century French inventors 19th-century French physicians 19th-century deaths from tuberculosis French Roman Catholics French pulmonologists Tuberculosis deaths in France