Relebactam is a chemical compound used in combination with antibiotics to improve their efficacy. As a
beta-lactamase inhibitor
Beta-lactamases, (β-lactamases) are enzymes () produced by bacteria that provide multi-resistance to beta-lactam antibiotics such as penicillins, cephalosporins, cephamycins, monobactams and carbapenems (ertapenem), although carbapenem ...
, it blocks the ability of bacteria to break down a
beta-lactam antibiotic
β-lactam antibiotics (beta-lactam antibiotics) are antibiotics that contain a beta-lactam ring in their chemical
structure. This includes penicillin derivatives (penams), cephalosporins and cephamycins (cephems), monobactams, carbapenems and ...
. In the United States, relebactam is approved for use in the combination
imipenem/cilastatin/relebactam (Recarbrio).
See also
*
Avibactam
Avibactam is a non-β-lactam Β-Lactamase inhibitor, β-lactamase inhibitor developed by Actavis (now Teva Pharmaceuticals, Teva) jointly with AstraZeneca. A new drug application for avibactam in Ceftazidime/avibactam, combination with ceftazidim ...
References
Antibiotics
Beta-lactamase inhibitors
Nitrogen heterocycles
4-Piperidinyl compounds
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