Rao Yi
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Rao Yi (; born 1962) is a Chinese
neurobiologist A neuroscientist (or neurobiologist) is a scientist who has specialised knowledge in neuroscience, a branch of biology that deals with the physiology, biochemistry, psychology, anatomy and molecular biology of neurons, neural circuits, and glial c ...
. A Ph.D. graduate from the
University of California, San Francisco The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It cond ...
, Rao held a Helen Hay Whitney fellowship at
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
and was on the faculty of
Washington University in St. Louis Washington University in St. Louis (WashU or WUSTL) is a private research university with its main campus in St. Louis County, and Clayton, Missouri. Founded in 1853, the university is named after George Washington. Washington University is r ...
and
Northwestern University Northwestern University is a private research university in Evanston, Illinois. Founded in 1851, Northwestern is the oldest chartered university in Illinois and is ranked among the most prestigious academic institutions in the world. Charte ...
before moving back to China to take up the deanship of
Peking University Peking University (PKU; ) is a public research university in Beijing, China. The university is funded by the Ministry of Education. Peking University was established as the Imperial University of Peking in 1898 when it received its royal charter ...
's School of Life Sciences in 2007 . He is currently the director the IDG/McGovern Institute for Brain Research at Peking University. He took office as the President of the
Capital Medical University Capital Medical University (CMU) ) is a public research university in Beijing, China. Capital Medical University was founded in 1960, with the original name of Beijing Second Medical College. Rankings Capital Medical University is listed as o ...
on June 25, 2019.


Personal life and education

Rao was born in
Jiangxi Jiangxi (; ; formerly romanized as Kiangsi or Chianghsi) is a landlocked province in the east of the People's Republic of China. Its major cities include Nanchang and Jiujiang. Spanning from the banks of the Yangtze river in the north int ...
in 1962. In college, he was friends with Mei Lin, who also became a neurobiologist later. In graduate school at Shanghai Medical University, Rao was roommates with , now also an eminent neurobiologist. At SMU, his interests began to turn to
molecular neurobiology Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject covers topics such as molecular neuroanatomy, mechanisms of molecular signaling in ...
. In 1985, Rao enrolled as a graduate student at the
University of California, San Francisco The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It cond ...
. He describes the atmosphere at UCSF as far more exciting than that to which he had previously been exposed in China. His advisors were Yuh-Nung and Lily Jan. He discovered the ''big brain'' gene, which is required for a binary decision in neural development: to form a neuron or an epidermal cell. He defended his doctoral thesis on molecular and genetic analysis of intercellular communication in ''
Drosophila ''Drosophila'' () is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species ...
''
neurogenesis Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells (NSCs). It occurs in all species of animals except the porifera (sponges) and placozoans. Types of NSCs include neuroepithelial cells (NECs) ...
at UCSF in 1991.


Career and research interests

After graduating from UCSF, Rao received a Helen Hay Whitney fellowship for postdoctoral research in the Department of Biochemistry and Molecular Biology at Harvard University, where he worked on embryonic induction in vertebrates. He then joined the faculty of
Washington University in St. Louis Washington University in St. Louis (WashU or WUSTL) is a private research university with its main campus in St. Louis County, and Clayton, Missouri. Founded in 1853, the university is named after George Washington. Washington University is r ...
in 1994, where he established his first laboratory. He moved to
Northwestern University Northwestern University is a private research university in Evanston, Illinois. Founded in 1851, Northwestern is the oldest chartered university in Illinois and is ranked among the most prestigious academic institutions in the world. Charte ...
in Chicago in 2004, and was named the university's first Elsa A. Swanson Research Professor in 2006. Other honours he received include the Esther A. and Joseph Klingenstein Fellowship in Neuroscience in 2000, as well as the Charles B. Wilson Brain Tumor Research Excellence Award in Neuroscience. He also served on the editorial board of ''The Journal of Neuroscience'', ''Developmental Biology'', ''Developmental Brain Research'', ''Neuroscience Research'' ''He moved back to China in 2007 to be the dean of
Peking University Peking University (PKU; ) is a public research university in Beijing, China. The university is funded by the Ministry of Education. Peking University was established as the Imperial University of Peking in 1898 when it received its royal charter ...
's School of Life Sciences.'' He stepped down from the deanship in 2013. In 1997, Rao discovered that a single origin gave rise to two eyes in frog and chicken embryos . In 1999, he demonstrated that the secreted protein encoded by the Slit gene was a repellent guidance cue for axons. He has later found that Slit could repel migrating neurons, chemotactic leukocytes and brain tumor cells. Rao has uncovered major components in the signal transduction pathways for Slit and the axon attractant Netrin . In China, Rao switched to studies of molecular and cellular mechanisms of behaviors and has found neurotransmitters required for aggression and courtship in Drosophila and the mouse.


Science funding reform advocacy

Rao Yi is one of the leading reformers of science and education in China . He participated directly in the reform or establishment of five institutes and writes about science and culture for a wide audience. While in the U.S., he began his involvement with academia in China, working with Lu Bai and Mei Lin to establish a joint lab in Shanghai in 1995. They then joined
Mu-ming Poo Mu-ming Poo (; born October 31, 1948) is a Chinese-American neuroscientist. He is the Paul Licht Distinguished Professor Emeritus at the University of California, Berkeley and the Founding Director of the Shanghai-based Institute of Neuroscienc ...
of UC Berkeley on a proposal to establish the Institute of Neuroscience in Shanghai in 1999. In 2002, Rao and Uli Schwarz of the Max Planck Institute established the Shanghai Institute of Advanced Studies at the Chinese Academy of Sciences, for which they served as co-directors till 2005. In 2004, Xiaodong Wang, Xingwang Deng and Rao established the National Institute of Biological Sciences, for which Rao served as an Associate Director for Academic Affairs until 2009. In 2004, Rao, Bai Lu and Chenlu Tsou advocated for changes in China's system of grants for scientific research, questioning the involvement of bureaucrats and the emphasis on connections rather than merit in a paper () which suggested alternatives to the Mid-to-Long Term Plan of Science and Technology. He levelled sharper criticisms in a 2010 ''
Science Science is a systematic endeavor that builds and organizes knowledge in the form of testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence for ...
'' editorial with fellow ex-American Shi Yigong () which drew widespread focus to corruption and embezzlement from research funds. The
Ministry of Science and Technology A Science Ministry or Department of Science is a ministry or other government agency charged with science. The ministry is often headed by a Minister for Science. List of Ministries of Science Many countries have a Ministry of Science or Ministry ...
disputed Shi and Rao's claims, stating that there was "zero tolerance" for misconduct. The year after the article, both Rao and Shi failed to be named to the
Chinese Academy of Sciences The Chinese Academy of Sciences (CAS); ), known by Academia Sinica in English until the 1980s, is the national academy of the People's Republic of China for natural sciences. It has historical origins in the Academia Sinica during the Republ ...
in the first round of voting among members in its biennial membership elections. Rao and Shi's failure to be named among the 145 candidates on the longlist for membership was widely believed to be tied to their criticisms, and in response Rao announced in a post on ScienceNet.cn that he would refuse to stand for election to the CAS again in the future. Since 2007, Rao successfully established the tenure track system in the School of Life Sciences, with international peer reviews of academic merits as the important criteria for hiring, promotion and firing . In 2012, Rao and Yigong Shi established the Center for Life Sciences, with Rao serving as the director of Peking part and Shi as the director of the Tsinghua part . In 2013, Rao established the IDG/McGovern Institute for Brain Research at Peking University and serves as its founding director . In 2018, Rao established the Chinese Institute for Brain Research (CIBR), Beijing and serves as its founding co-director . In 2019, Rao was appointed the president of the Capital Medical University .


Other views

In 2009, two years after his return to China, Rao renounced his U.S. citizenship; in a written statement to the
U.S. embassy in Beijing The Embassy of the United States in Beijing is the diplomatic mission of the United States in China. It serves as the administrative office of the United States Ambassador to China. The embassy complex is in Chaoyang District, Beijing, Chaoyang ...
during that process, he criticized the US government for its behaviors after the
September 11th attacks The September 11 attacks, commonly known as 9/11, were four coordinated suicide terrorist attacks carried out by al-Qaeda against the United States on Tuesday, September 11, 2001. That morning, nineteen terrorists hijacked four commercial ...
. Rao went on to a major Chinese TV program in 2016 and denounced Donald Trump . Rao had failed to obtain a visa to visit the US since 2016. A large number of Chinese viewed Rao as ridiculous in denouncing Trump in 2016. However, this turned by 2020 when most Chinese were also against Trump. Rao is a supporter of
genetically modified food Genetically modified foods (GM foods), also known as genetically engineered foods (GE foods), or bioengineered foods are foods produced from organisms that have had changes introduced into their DNA using the methods of genetic engineering. Gene ...
, and believes that even if China opposes GM food, it will simply result in the collapse of local companies while foreign companies strengthen their hold on the industry. Rao came under criticism from both
Kuomintang The Kuomintang (KMT), also referred to as the Guomindang (GMD), the Nationalist Party of China (NPC) or the Chinese Nationalist Party (CNP), is a major political party in the Republic of China, initially on the Chinese mainland and in Tai ...
and
Democratic Progressive Party The Democratic Progressive Party (DPP) is a Taiwanese nationalist and centre-left political party in the Republic of China (Taiwan). Controlling both the Republic of China presidency and the unicameral Legislative Yuan, it is the majori ...
politicians in
Taiwan Taiwan, officially the Republic of China (ROC), is a country in East Asia, at the junction of the East and South China Seas in the northwestern Pacific Ocean, with the People's Republic of China (PRC) to the northwest, Japan to the nort ...
for his private letter relating to the addresses of Beijing and Taiwan researchers involved in scientific collaboration. In a 2011 letter to National Science Council head Lee Lou-chuang, Rao proposed that a paper in which Peking University researchers had collaborated with
National Tsing Hua University National Tsing Hua University (NTHU; ) is a public research university in Hsinchu City, Taiwan. National Tsing Hua University was first founded in Beijing. After the Chinese Civil War, the then-president of the university, Mei Yiqi, and other ...
researchers in Taiwan identify each institution's location without the use of political terms "People's Republic" or "Republic". This would lead to Peking University's location being listed as "Beijing, China", and NTHU as located in " Taipei, China". However, Taiwan's
National Science Council The National Science and Technology Council (NSTC; ) is a statutory agency of Executive Yuan of the Republic of China (Taiwan) for the promotion and funding of academic research, development of science and technology and science parks. NSTC is ...
requires researchers it funds to list their location either as "Taiwan" or "Taiwan, Republic of China". The director of Taiwan's National Science Council did not reply to Rao's letter, but revealed it to the general public of Taiwan instead. KMT caucus whip Chao Li-yun () conveyed the KMT's condemnation of Rao for his suggestion, while Chen Ting-fei of the DPP criticised President
Ma Ying-jeou Ma Ying-jeou ( zh, 馬英九, born 13 July 1950) is a Hong Kong-born Taiwanese politician who served as president of the Republic of China from 2008 to 2016. Previously, he served as justice minister from 1993 to 1996 and mayor of Taipei from ...
for "submitting to humiliation" by not speaking up about the matter.


Selected works


Scientific research

*


Opinion and popular press

*With Lu Bai and Tsou Chen-Lu: * *With Shi Yigong:


References


External links


Personal blog on ScienceNet.cn

Personal blog on Caixin.com
{{DEFAULTSORT:Rao, Yi 1962 births Living people Chinese neuroscientists Fudan University alumni Northwestern University faculty Peking University faculty Former United States citizens Biologists from Jiangxi University of California, San Francisco alumni Washington University in St. Louis faculty Chinese molecular biologists Educators from Jiangxi