Ramachandra "(Ram)" S. Hosmane (1944-) is a retired Senior Professor of Organic Chemistry at
University of Maryland, Baltimore County
The University of Maryland, Baltimore County (UMBC) is a public research university in Baltimore County, Maryland. It has a fall 2022 enrollment of 13,991 students, 61 undergraduate majors, over 92 graduate programs (38 master, 25 doctoral, ...
. Dr. Hosmane has over 160 peer-reviewed research publications in reputed international journals.
He holds seven U.S. and World patents,
some of which have been licensed to industries. His current research focus is on drug discovery for dual inhibition of
HCV and
HIV
The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
as well as lung, breast, and prostate cancers.
Early life
Ram Hosmane was born in
Gokarna Gokarna may refer to:
Places
* Gokarna, Karnataka, a town in Karnataka, India
* Gokarna, West Bengal, a village in West Bengal, India
* Gokarnamatam, a village in Andhra Pradesh, India
* Trincomalee, a city in Eastern Province, Sri Lanka also known ...
,
Uttara Kannada
Uttara Kannada is a district in the Indian state of Karnataka. Uttara Kannada District is a major coastal district of Karnataka, and currently holding the title of the largest district in Karnataka. It is bordered by the state of Goa and Bela ...
, India and completed
Bhadrakali High School, Gokarna
Bhadrakali High School, Gokarna is one of the oldest high schools in Kumta taluk, Uttar Kannada district, India. Bhadrkali is the name of the Hindu Goddess Kali. The school is named after the Goddess Kali.
The school was founded in 1946 < ...
. In 1966, he earned a B.Sc. in chemistry from Karnataka University,
Dharwar
Dharwad (), also known as Dharwar, is a city located in the north western part of the Indian state of Karnataka. It is the headquarters of the Dharwad district of Karnataka and forms a contiguous urban area with the city of Hubballi. It was merge ...
, followed by a M.Sc. degree in
Organic Chemistry
Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; ...
from the same institution in 1968.
Career
Hosmane moved to the United States in the early 1970s to pursue a doctoral degree in
organic synthesis
Organic synthesis is a special branch of chemical synthesis and is concerned with the intentional construction of organic compounds. Organic molecules are often more complex than inorganic compounds, and their synthesis has developed into one o ...
and
medicinal chemistry
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and developm ...
at the
University of South Florida
The University of South Florida (USF) is a public research university with its main campus located in Tampa, Florida, and other campuses in St. Petersburg and Sarasota. It is one of 12 members of the State University System of Florida. USF is ...
, where he earned
M.S.
A Master of Science ( la, Magisterii Scientiae; abbreviated MS, M.S., MSc, M.Sc., SM, S.M., ScM or Sc.M.) is a master's degree in the field of science awarded by universities in many countries or a person holding such a degree. In contrast to ...
(1976) and
Ph.D.
A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is a ...
degrees (1978). After completing his postdoctoral training (1979–82) at the
University of Illinois, Urbana-Champaign
The University of Illinois Urbana-Champaign (U of I, Illinois, University of Illinois, or UIUC) is a public land-grant research university in Illinois in the twin cities of Champaign and Urbana. It is the flagship institution of the Universi ...
, Hosmane joined
UMBC
The University of Maryland, Baltimore County (UMBC) is a public research university in Baltimore County, Maryland. It has a fall 2022 enrollment of 13,991 students, 61 undergraduate majors, over 92 graduate programs (38 master, 25 doctoral, ...
as an assistant professor in 1982 and was promoted to associate professor with academic tenure in 1986. He was promoted to the rank of full professor in 1994.
His research work has been supported by about 50 grants from federal and state agencies such as the
National Institutes of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
and the Maryland Industrial Partnerships (MIPS), and private foundations such as the
American Heart Association
The American Heart Association (AHA) is a nonprofit organization in the United States that funds cardiovascular medical research, educates consumers on healthy living and fosters appropriate cardiac care in an effort to reduce disability and death ...
,
American Cancer Society
The American Cancer Society (ACS) is a nationwide voluntary health organization dedicated to eliminating cancer. Established in 1913, the society is organized into six geographical regions of both medical and lay volunteers operating in more than ...
, and the Petroleum Research Fund
as well as a variety of industrial sources. He has contributed significantly to the development of
organic
Organic may refer to:
* Organic, of or relating to an organism, a living entity
* Organic, of or relating to an anatomical organ
Chemistry
* Organic matter, matter that has come from a once-living organism, is capable of decay or is the product ...
and
medicinal chemistry
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and developm ...
.
He was honored as the University Presidential Research Professor for 1998–2001. In 1996, he was recognized as Outstanding Mentor of Project SEED of the American Chemical Society.
Two major research areas of Hosmane include
blood substitute
A blood substitute (also called artificial blood or blood surrogate) is a substance used to mimic and fulfill some functions of biological blood. It aims to provide an alternative to blood transfusion, which is transferring blood or blood-based ...
s based on
hemoglobin
Hemoglobin (haemoglobin BrE) (from the Greek word αἷμα, ''haîma'' 'blood' + Latin ''globus'' 'ball, sphere' + ''-in'') (), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein present in red blood cells (erythrocyte ...
s and the discovery of
antiviral
Antiviral drugs are a class of medication used for treating viral infections. Most antivirals target specific viruses, while a broad-spectrum antiviral is effective against a wide range of viruses. Unlike most antibiotics, antiviral drugs do no ...
and
anticancer An anticarcinogen (also known as a carcinopreventive agent) is a substance that counteracts the effects of a carcinogen or inhibits the development of cancer. Anticarcinogens are different from anticarcinoma agents (also known as anticancer or ant ...
compounds based on ring-expanded nucleoside structures. Th
Hosmane is a managing editor of ''
Current Topics in Medicinal Chemistry'' and ''
Frontiers in Bioscience
''Frontiers in Bioscience'' is a peer reviewed scientific journal. It was established in 1996 and covers all biological and medical sciences. The editor-in-chief is Graham Pawelec. The journal consists of three sections: ''Landmark Edition'', ''Sc ...
'', part of the
Frontiers Media
Frontiers Media SA is a publisher of peer-reviewed, open access, scientific journals currently active in science, technology, and medicine. It was founded in 2007 by Kamila and Henry Markram, and has since expanded to other academic fields. Fro ...
group, and Regional Editor, ''
Molecules
A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioche ...
'' .
[http://www.mdpi.org/molecules/]
References
{{DEFAULTSORT:Hosmane, Ramachandra S.
1944 births
Indian organic chemists
Living people
People from Uttara Kannada
University of Maryland, Baltimore County faculty
Karnatak University alumni
Scientists from Karnataka