RU-24,969 is a

drug A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...

and

research chemical Research chemicals are chemical substances used by scientists for medical and scientific research purposes. One characteristic of a research chemical is that it is for laboratory research use only; a research chemical is not intended for human o ...

widely used in scientific studies. It is a selective

agonist An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...

at the 5-HT_1A and 5-HT_1B

receptors Receptor may refer to: *Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds to a n ...

, with preference for the latter. As with other 5-HT_1B agonists such as

CP-94,253 CP-94253 is a drug which acts as a potent and selective serotonin 5-HT1B receptor Receptor may refer to: * Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse *Recept ...

, RU-24,969 has been found to increase the reinforcing properties of cocaine, suggesting a role for 5-HT_1B receptors in

cocaine addiction Cocaine dependence is a neurological disorder that is characterized by withdrawal symptoms upon cessation from cocaine use. It also often coincides with cocaine addiction which is a biopsychosocial disorder characterized by persistent use of coc ...

References

5-HT1A agonists 5-HT1B agonists 5-HT7 agonists Phenol ethers Tetrahydropyridines {{nervous-system-drug-stub

See also

References