Replication protein A 14 kDa subunit is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''RPA3''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Interactions
RPA3 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with
replication protein A1
Replication protein A 70 kDa DNA-binding subunit is a protein that in humans is encoded by the ''RPA1'' gene.
Interactions
Replication protein A1 has been shown to interact with:
* BRCA2,
* BLM,
* MCM2,
* MCM4,
* MCM6,
* MCM7,
* MUTYH, ...
and
replication protein A2
Replication protein A 32 kDa subunit is a protein that in humans is encoded by the ''RPA2'' gene.
Interactions
RPA2 has been shown to interact with:
* Cyclin O,
* DNA-PKcs,
* Ku70,
* MEN1,
* RPA3,
* Replication protein A1,
* STAT3,
* ...
.
[
]
See also
* Single-stranded binding protein
Single-stranded binding proteins (SSBs) are a class of proteins that have been identified in both viruses and organisms from bacteria to humans.
Viral SSB
Although the overall picture of ''human cytomegalovirus'' (HHV-5) DNA synthesis appears ...
* Replication protein A
Replication protein A (RPA) is the major protein that binds to single-stranded DNA (ssDNA) in eukaryotic cells. In vitro, RPA shows a much higher affinity for ssDNA than RNA or double-stranded DNA. RPA is required in replication, recombinatio ...
* Replication protein A1
Replication protein A 70 kDa DNA-binding subunit is a protein that in humans is encoded by the ''RPA1'' gene.
Interactions
Replication protein A1 has been shown to interact with:
* BRCA2,
* BLM,
* MCM2,
* MCM4,
* MCM6,
* MCM7,
* MUTYH, ...
* Replication protein A2
Replication protein A 32 kDa subunit is a protein that in humans is encoded by the ''RPA2'' gene.
Interactions
RPA2 has been shown to interact with:
* Cyclin O,
* DNA-PKcs,
* Ku70,
* MEN1,
* RPA3,
* Replication protein A1,
* STAT3,
* ...
References
Further reading
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