Ras-related protein Rab-6A is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''RAB6A''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
located in the eleventh chromosome.
Its main function is the regulation of protein transport from the
Golgi complex
The Golgi apparatus (), also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells. Part of the endomembrane system in the cytoplasm, it packages proteins into membrane-bound vesicles insi ...
to the
endoplasmic reticulum
The endoplasmic reticulum (ER) is, in essence, the transportation system of the eukaryotic cell, and has many other important functions such as protein folding. It is a type of organelle made up of two subunits – rough endoplasmic reticulum ( ...
and the exocytosis along with the microtubules.
Interactions
RAB6A has been shown to
interact
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with:
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BICD1,
DCTN1
Dynactin subunit 1 is a protein that in humans is encoded by the ''DCTN1'' gene.
Function
This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 23 subunits (11 individual proteins ranging in size from 22 to ...
ERC1
ELKS/RAB6-interacting/CAST family member 1 is a protein that in humans is encoded by the ''ERC1'' gene. The name ELKS is derived from "protein rich in the amino acids E, L, K and S"
The protein encoded by this gene is a member of a family of R ...
,KIF20A
Kinesin-like protein KIF20A is a protein that in humans is encoded by the ''KIF20A'' gene.
Interactions
KIF20A has been shown to interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3 ...
.
References
Further reading
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