R. Kip Guy is an American pharmaceutical chemist. , he is the dean of the University of Kentucky College of Pharmacy.

Early life and education

Guy was born in Alabama but was raised in various places including

Jacks Creek, Tennessee Jacks Creek (or Jack's Creek) is an unincorporated community in Chester County, Tennessee, United States. History The area was settled in the 1820s.

, England, and Ohio. He completed his Bachelor of Arts degree in chemistry from Reed College before working as a process development chemist in the process translation unit at IBM Research. Following this, he received his PhD in organic chemistry in 1996 based on the total synthesis of taxol from the Scripps Research Institute. His thesis was conducted under the guidance of

K. C. Nicolaou Kyriacos Costa Nicolaou ( el, Κυριάκος Κ. Νικολάου; born July 5, 1946) is a Cypriot-American chemist known for his research in the area of natural products total synthesis. He is currently Harry C. and Olga K. Wiess Professor of ...

and was titled ''An Exploration of the Chemistry of Taxol.'' After this, Guy accepted a postdoctoral fellowship in cellular biology at the

University of Texas Southwestern Medical Center The University of Texas Southwestern Medical Center (UT Southwestern or UTSW) is a public academic health science center in Dallas, Texas. With approximately 18,800 employees, more than 2,900 full-time faculty, and nearly 4 million outpatient vi ...

and additional training in physiology at the

Woods Hole Oceanographic Institution The Woods Hole Oceanographic Institution (WHOI, acronym pronounced ) is a private, nonprofit research and higher education facility dedicated to the study of marine science and engineering. Established in 1930 in Woods Hole, Massachusetts, it i ...

Career

After completing his postdoctoral fellowship, Guy joined the

University of California, San Francisco The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It cond ...

as an assistant professor with joint appointments in pharmaceutical chemistry and cellular and molecular pharmacology. While there, he established an independent laboratory to develop strategies for targeting and signaling systems for testosterone and estrogen. In 2005, Guy moved to

St. Jude Children's Research Hospital St. Jude Children's Research Hospital is a pediatric treatment and research facility located in Memphis, Tennessee. Founded in 1962, it is a 501(c)(3) designated nonprofit medical corporation which focuses on children's catastrophic diseases, pa ...

to found and chair its new department of chemical biology and therapeutics as the Robert J. Ulrich Chair in Chemical Biology and Therapeutics. While serving in this position, he led the anti-malarial drug-discovery effort and preclinical development of SJ733. In October 2016, Guy left St. Jude's to become the dean of the University of Kentucky College of Pharmacy. While serving in this role, he continued his research from St. Jude studying blocking cancer-causing proteins on a cellular level. In 2017, his research team became the first to show that protein interaction controlled by N-terminal acetylation could be blocked. Following this discovery, Guy was elected a Fellow of the

American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific respons ...

(AAAS).

Personal life

Guy and his wife, pediatric psychologist Caitlin Allen, have two children together.

References

External links

{{DEFAULTSORT:Guy, R. Kip Living people Physicians from Alabama Scientists from Alabama Reed College alumni University of Kentucky faculty University of California, San Francisco faculty Fellows of the American Association for the Advancement of Science Year of birth missing (living people)