Quassinoids are degraded

triterpene Triterpenes are a class of chemical compounds composed of three terpene units with the molecular formula C30H48; they may also be thought of as consisting of six isoprene units. Animals, plants and fungi all produce triterpenes, including squale ...

lactones (similar to

limonoids Limonoids are phytochemicals of the triterpenoid class which are abundant in sweet or sour-scented citrus fruit and other plants of the families Cucurbitaceae, Rutaceae, and Meliaceae. Certain limonoids are antifeedants such as azadirachtin from ...

) of the

Simaroubaceae The Simaroubaceae are a small, mostly tropical, family in the order Sapindales. In recent decades, it has been subject to much taxonomic debate, with several small families being split off. A molecular phylogeny of the family was published in 200 ...

plant family grouped into C-18, C-19, C-20, C-22 and C-25 types. The prototypical member of the group,

quassin Quassin is a white, bitter, crystalline substance that is the prototypical example of the family of quassinoids. It can be extracted from the quassia tree, from which it gets its name. It was first isolated in 1937 and its chemical structure was ...

, was first described in the 19th century from plants of the genus ''

Quassia ''Quassia'' ( or ) is a plant genus in the family Simaroubaceae. Its size is disputed; some botanists treat it as consisting of only one species, ''Quassia amara'' from tropical South America, while others treat it in a wide circumscription as a ...

'' from which it gets its name. It was isolated in 1937 and its structure elucidated in 1961. They are a biologically potent class of natural products, possessing antimalarial, antifeedant, insecticidal, anti-inflammatory, and anticancer properties. The quassinoid bruceantin reached two separate phase II clinical trials in 1982 and 1983. Other quassinoids include: * Bruceanols * Bruceolide *

Eurycomanone Eurycomanone is a chemical compound that has been isolated from ''Eurycoma longifolia'', also known as the longjack plant or tongkat ali. Mechanism of action Eurycomanone is thought to be central to the sex-hormone increasing effects of ''Euryc ...

* Gutolactone * Isobrucein A * Neoquassin * Nigakihemiacetal A * Quassimarin * Samaderines * Simalikalactones

References

External links

* * {{wiktionary inline, quassinoid Heterocyclic compounds with 4 rings