Pyraclostrobin
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Pyraclostrobin is a quinone outside inhibitor ( QI)-type
fungicide Fungicides are biocidal chemical compounds or biological organisms used to kill parasitic fungi or their spores. A fungistatic inhibits their growth. Fungi can cause serious damage in agriculture, resulting in critical losses of yield, quality, ...
used in
agriculture Agriculture or farming is the practice of cultivating plants and livestock. Agriculture was the key development in the rise of sedentary human civilization, whereby farming of domesticated species created food surpluses that enabled people to ...
. Among the QIs, it lies within the
strobilurin Strobilurins are a group of natural products and their synthetic analogs. A number of strobilurins are used in agriculture as fungicides. They are part of the larger group of QIs (Quinone outside Inhibitors), which act to inhibit the respiratory c ...
chemical class.


Use

Pyraclostrobin is used to protect ''
Fragaria ''Fragaria'' () is a genus of flowering plants in the rose family, Rosaceae, commonly known as strawberries for their edible fruits. There are more than 20 described species and many hybrids and cultivars. The most common strawberries grown com ...
'', ''
Rubus idaeus ''Rubus idaeus'' (raspberry, also called red raspberry or occasionally European red raspberry to distinguish it from other raspberry species) is a red-fruited species of ''Rubus'' native to Europe and northern Asia and commonly cultivated in othe ...
'', ''
Vaccinium corymbosum ''Vaccinium corymbosum'', the northern highbush blueberry, is a North American species of blueberry which has become a food crop of significant economic importance. It is native to eastern Canada and the eastern and southern United States, from ...
'', ''
Ribes rubrum The redcurrant or red currant (''Ribes rubrum'') is a member of the genus ''Ribes'' in the gooseberry family. It is native to western Europe. The species is widely cultivated and has escaped into the wild in many regions. Description ''Ribes r ...
'', ''
Ribes uva-crispa ''Ribes uva-crispa'', known as gooseberry or European gooseberry, is a species of flowering shrub in the currant family, Grossulariaceae. It is native to Europe, the Caucasus and northern Africa. Gooseberry bushes produce an edible fruit and ar ...
'',
blackberry The blackberry is an edible fruit produced by many species in the genus ''Rubus'' in the family Rosaceae, hybrids among these species within the subgenus ''Rubus'', and hybrids between the subgenera ''Rubus'' and ''Idaeobatus''. The taxonomy of ...
(various ''
Rubus ''Rubus'' is a large and diverse genus of flowering plants in the rose family, Rosaceae, subfamily Rosoideae, with over 1,350 species. Raspberries, blackberries, and dewberries are common, widely distributed members of the genus. Most of these ...
'' spp.), and '' Pistachio vera''.


Target pathogens

Pyraclostrobin is used against ''
Botrytis cinerea ''Botrytis cinerea'' is a necrotrophic fungus that affects many plant species, although its most notable hosts may be wine grapes. In viticulture, it is commonly known as "botrytis bunch rot"; in horticulture, it is usually called "grey mould" or ...
'' and ''
Alternaria alternata ''Alternaria alternata'' is a fungus which has been recorded causing leaf spot and other diseases on over 380 host species of plant. It is an opportunistic pathogen on numerous hosts causing leaf spots, rots and blights on many plant parts. It ...
''.


Resistance

Resistant populations have been identified in: *''
Botrytis cinerea ''Botrytis cinerea'' is a necrotrophic fungus that affects many plant species, although its most notable hosts may be wine grapes. In viticulture, it is commonly known as "botrytis bunch rot"; in horticulture, it is usually called "grey mould" or ...
'' on ''
Fragaria ''Fragaria'' () is a genus of flowering plants in the rose family, Rosaceae, commonly known as strawberries for their edible fruits. There are more than 20 described species and many hybrids and cultivars. The most common strawberries grown com ...
'' in the
Carolinas The Carolinas are the U.S. states of North Carolina and South Carolina, considered collectively. They are bordered by Virginia to the north, Tennessee to the west, and Georgia to the southwest. The Atlantic Ocean is to the east. Combining Nort ...
, conferred by the G143A mutation in the partial
cytochrome b Cytochrome b within both molecular and cell biology, is a protein found in the mitochondria of eukaryotic cells. It functions as part of the electron transport chain and is the main subunit of transmembrane cytochrome bc1 and b6f complexes. F ...
(CYTB) gene. *''
Botrytis cinerea ''Botrytis cinerea'' is a necrotrophic fungus that affects many plant species, although its most notable hosts may be wine grapes. In viticulture, it is commonly known as "botrytis bunch rot"; in horticulture, it is usually called "grey mould" or ...
'' on ''Fragaria'', ''
Rubus idaeus ''Rubus idaeus'' (raspberry, also called red raspberry or occasionally European red raspberry to distinguish it from other raspberry species) is a red-fruited species of ''Rubus'' native to Europe and northern Asia and commonly cultivated in othe ...
'', ''
Vaccinium corymbosum ''Vaccinium corymbosum'', the northern highbush blueberry, is a North American species of blueberry which has become a food crop of significant economic importance. It is native to eastern Canada and the eastern and southern United States, from ...
'', ''
Ribes rubrum The redcurrant or red currant (''Ribes rubrum'') is a member of the genus ''Ribes'' in the gooseberry family. It is native to western Europe. The species is widely cultivated and has escaped into the wild in many regions. Description ''Ribes r ...
'', ''
Ribes uva-crispa ''Ribes uva-crispa'', known as gooseberry or European gooseberry, is a species of flowering shrub in the currant family, Grossulariaceae. It is native to Europe, the Caucasus and northern Africa. Gooseberry bushes produce an edible fruit and ar ...
'', and
blackberry The blackberry is an edible fruit produced by many species in the genus ''Rubus'' in the family Rosaceae, hybrids among these species within the subgenus ''Rubus'', and hybrids between the subgenera ''Rubus'' and ''Idaeobatus''. The taxonomy of ...
(various ''
Rubus ''Rubus'' is a large and diverse genus of flowering plants in the rose family, Rosaceae, subfamily Rosoideae, with over 1,350 species. Raspberries, blackberries, and dewberries are common, widely distributed members of the genus. Most of these ...
'' spp.) in
Northern Germany Northern Germany (german: link=no, Norddeutschland) is a linguistic, geographic, socio-cultural and historic region in the northern part of Germany which includes the coastal states of Schleswig-Holstein, Mecklenburg-Vorpommern and Lower Saxony an ...
. *''
Botrytis cinerea ''Botrytis cinerea'' is a necrotrophic fungus that affects many plant species, although its most notable hosts may be wine grapes. In viticulture, it is commonly known as "botrytis bunch rot"; in horticulture, it is usually called "grey mould" or ...
'' on ''Fragaria'' in
Florida Florida is a state located in the Southeastern region of the United States. Florida is bordered to the west by the Gulf of Mexico, to the northwest by Alabama, to the north by Georgia, to the east by the Bahamas and Atlantic Ocean, and to ...
. *''
Alternaria alternata ''Alternaria alternata'' is a fungus which has been recorded causing leaf spot and other diseases on over 380 host species of plant. It is an opportunistic pathogen on numerous hosts causing leaf spots, rots and blights on many plant parts. It ...
'' on '' Pistachio vera'' in
California California is a U.S. state, state in the Western United States, located along the West Coast of the United States, Pacific Coast. With nearly 39.2million residents across a total area of approximately , it is the List of states and territori ...
.


Geography of use


United States

Pyraclostrobin was widely used throughout the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
, but especially in the
Upper Midwest The Upper Midwest is a region in the northern portion of the U.S. Census Bureau's Midwestern United States. It is largely a sub-region of the Midwest. Although the exact boundaries are not uniformly agreed-upon, the region is defined as referring ...
.


Off-target toxicity

Although toxic, and recommended to be avoided by humans, pyraclostrobin is of temporary and low toxicity, that is to say it is merely an irritant of eyes and skin. It does cause some degree of reproductive and developmental failure in mammals but does not absorb well through the skin. It is likely to
bioaccumulate Bioaccumulation is the gradual accumulation of substances, such as pesticides or other chemicals, in an organism. Bioaccumulation occurs when an organism absorbs a substance at a rate faster than that at which the substance is lost or eliminated ...
in aquatic organisms.


Residues in diet

Pyraclostrobin does not accumulate in foods to a significant degree.


Biodegradability

Pyraclostrobin is described by one source as not very
biodegradable Biodegradation is the breakdown of organic matter by microorganisms, such as bacteria and fungi. It is generally assumed to be a natural process, which differentiates it from composting. Composting is a human-driven process in which biodegradati ...
, and by another as possibly significantly biodegradable.


References


Further reading

* *{{cite web , title=Pyraclostrobine , website=NIST WebBook , publisher=
National Institute of Standards and Technology The National Institute of Standards and Technology (NIST) is an agency of the United States Department of Commerce whose mission is to promote American innovation and industrial competitiveness. NIST's activities are organized into physical sci ...
, url=http://webbook.nist.gov/cgi/inchi/InChI%3D1S/C19H18ClN3O4/c1-25-19(24)23(26-2)17-6-4-3-5-14(17)13-27-18-11-12-22(21-18)16-9-7-15(20)8-10-16/h3-12H%2C13H2%2C1-2H3 , access-date=2021-03-02 Fungicides Carbamates Pyrazoles Anilines Chloroarenes Strobilurins