Parity (biology)

In biology and human medicine, gravidity and parity are the number of times a woman is or has been pregnant (gravidity) and carried the pregnancies to a viable gestational age (parity). These terms are usually coupled, sometimes with additional terms, to indicate more details of the woman's obstetric history. When using these terms:
* Gravida indicates the number of times a woman is or has been pregnant, regardless of the pregnancy outcome. A current pregnancy, if any, is included in this count. A multiple pregnancy (e.g., twins, triplets, etc.) is counted as 1.
* Parity, or "para", indicates the number of births (including live births and stillbirths) where pregnancies reached viable gestational age. A multiple pregnancy (e.g., twins, triplets, etc.) carried to viable gestational age is still counted as 1.
* Abortus is the number of pregnancies that were lost prior to viable gestational age for any reason, including induced abortions or miscarriages but not stillbirths. The abortus term is sometimes dropped when no pregnancies have been lost.

Gravidity in human medicine

In human medicine, "gravidity" refers to the number of times a woman has been pregnant, regardless of whether the pregnancies were interrupted or resulted in a live birth. “Gravidity” is an important component of a patient’s reproductive history, as it provides insight into the risk factors that the patient has for pregnancy outcomes, such as risk for gestational diabetes, pre-ecclampsia, spontaneous abortion, preterm birth, fetal growth restriction, and more. The gravidity of the patient is associated with risk for other conditions as well, including risk for breast, ovarian, and endometrial cancer. Knowing a patient’s obstetric history in a prenatal assessment or early in gestation allows the patient to receive early intervention to prevent these associated risks.

* The term "gravida" can be used to refer to a pregnant woman.
* A "nulligravida" is a woman who has never been pregnant.
* A "primigravida" is a woman who is pregnant for the first time or has been pregnant once.
* A "multigravida" or "secundigravida" is a woman who has been pregnant more than once.

Terms such as "gravida 0", referring to a nulligravida, "gravida 1" for a primigravida, and so on, can also be used. The term "elderly primigravida" has also been used to refer to a woman in their first pregnancy who is at least 35 years old. Advanced maternal age, the term "gravid" ( la, gravidus "burdened, heavy") is used to describe the condition of an animal (most commonly fish or reptiles) when carrying eggs internally. For example, ''Astatotilapia burtoni'' females can transform between reproductive states, one of which is gravid, and the other non-gravid. In entomology it describes a mated female insect.

Parity in medicine

In human medicine, ''parity'' is the number of pregnancies carried by a woman for at least 20 weeks (duration varies from region to region, 20 – 28 weeks, depending upon age of viability). If a woman carries the fetus to viable age, even if ultimately the fetus is born deceased, this still counts as an instance of parity, as parity is based on the time of gestation prior to a birth, and not the status of the offspring once born.

A woman who has never carried a pregnancy beyond 20 weeks is ''nulliparous'' and is called a ''nullipara'' or ''para 0''.F. Gary Cunningham, 2005. Williams Obstetrics, 22nd Edition, McGraw-Hill Companies. A woman who has given birth once is ''primiparous'' and is referred to as a ''primipara'' or ''primip''. A woman who has given birth two, three, or four times is multiparous and is called a ''multip''. ''Grand multipara'' describes the condition of having given birth five or more times.

Like gravidity, parity may also be counted. A woman who has given birth one or more times can also be referred to as para 1, para 2, para 3, and so on.

Viable gestational age varies from region to region.

Nulliparity

A ''nulliparous'' () woman (a ''nullipara'' or ''para 0'') has never given birth. It includes women who have experienced spontaneous miscarriages and induced abortions before the mid-point of pregnancy, but not women who have experienced pregnancy loss after 20 weeks. Nulliparity has been implicated in the development of various complications during pregnancy including preeclampsia, gestational diabetes and pre-term labor.

Long-term and permanent nulliparity () are risk factors for breast cancer. For instance, a meta-analysis of 8 population-based studies in the Nordic countries found that never giving birth was associated with a 30% increase in the risk of breast cancer compared with women who have given birth, and for every 2 births, the risk was reduced by about 16%. Women having their first birth after the age of 35 years had a 40% increased risk compared to those with a first birth before the age of 20 years.

Parity in biology

In agriculture, parity in biology is a factor in productivity in domestic animals kept for milk production. Animals that have given birth once are described as "primiparous"; those that have given birth more than once are described as "pluriparous". Those that have given birth twice may also be described as "secondiparous", in which case "pluriparous" is applied to those that have given birth three times or more.

Recording systems

A number of systems are incorporated into a woman's obstetric history to record the number of past pregnancies and pregnancies carried to viable age. These include:
* The gravida/para/abortus (GPA) system, or sometimes just ''gravida/para'' (GP), is one such shorthand. For example, the obstetric history of a woman who has had two pregnancies (both of which resulted in live births) would be noted as G₂P₂. The obstetric history of a woman who has had four pregnancies, one of which was a miscarriage before 20 weeks, would be noted in the GPA system as G₄P₃A₁ and in the GP system as G₄P₃. The obstetric history of a woman who has had one pregnancy of twins with successful outcomes would be noted as G₁P₁₊₁.
* TPAL is one of the methods to provide a quick overview of a person's obstetric history. In TPAL, the T refers to term births (after 37 weeks' gestation), the P refers to premature births, the A refers to abortions, and the L refers to living children. When reported, the "abortions" number refers to the total number of spontaneous or induced abortions and miscarriages, including ectopic pregnancies, prior to 20 weeks. If a fetus is aborted after 20 weeks, spontaneously or electively, then it is counted as a premature birth and P will increase but L will not. The TPAL is described by numbers separated by hyphens. Multiple births (twins, triplets and higher multiples) count as one pregnancy (gravidity) and as one birth. For example, a pregnant woman who carried one pregnancy to term with a surviving infant; carried one pregnancy to 35 weeks with surviving twins; carried one pregnancy to 9 weeks as an ectopic (tubal) pregnancy; and has three living children would have a TPAL annotation of T1, P1, A1, L3. This could also be written as 1-1-1-3.
* The term GTPAL is used when the TPAL is prefixed with gravidity, and GTPALM when GTPAL is followed by number of multiple pregnancies. For example, the gravidity and parity of a woman who has given birth at term once and has had one miscarriage at 12 weeks would be recorded as G2 T1 P0 A1 L1. This notation is not standardized and can lead to misinterpretations.

Though similar, GPA should not be confused with the TPAL system, the latter of which may be used to provide information about the number of miscarriages, preterm births, and live births by dropping the "A" from "GPA" and including four separate numbers after the "P", as in G₅P₃₁₁₄. This TPAL form indicates five pregnancies, with three term births, one preterm birth, one induced abortion or miscarriage, and four living children.

Criticism

In obstetrics, the term can lead to some ambiguity for events occurring between 20 and 24 weeks, and for multiple pregnancies.

References

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