PGG-glucan
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Poly- -6-D-glucopyranosyl- -3-D-glucopyranose glucan (PGG glucan, proprietary name Betafectin) is an anti-infective agent and a form or type of
beta-glucan Beta-glucans, β-glucans comprise a group of β-D-glucose polysaccharides ( glucans) naturally occurring in the cell walls of cereals, bacteria, and fungi, with significantly differing physicochemical properties dependent on source. Typically, ...
. Betafectin is a PGG-glucan, a novel β-(1,6) branched β-(1,3) glucan, purified from the cell walls of ''
Saccharomyces cerevisiae ''Saccharomyces cerevisiae'' () (brewer's yeast or baker's yeast) is a species of yeast (single-celled fungus microorganisms). The species has been instrumental in winemaking, baking, and brewing since ancient times. It is believed to have been o ...
''. Effect on progenitor blood cells
/ref> It is a
macrophage Macrophages (abbreviated as M φ, MΦ or MP) ( el, large eaters, from Greek ''μακρός'' (') = large, ''φαγεῖν'' (') = to eat) are a type of white blood cell of the immune system that engulfs and digests pathogens, such as cancer cel ...
-specific
immunomodulator Immunotherapy or biological therapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as ''activation immunotherapies,'' while immunotherap ...
.


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Clinical trial in surgical patients
Immunology {{pharma-stub