Purine Imidazole-ring Cyclase
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The enzyme purine imidazole-ring cyclase (EC 4.3.2.4)
catalyzes Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the chemical reaction :DNA 4,6-diamino-5-formamidopyrimidine \rightleftharpoons DNA adenine + H2O This enzyme belongs to the family of
lyase In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. ...
s, specifically amidine lyases. The systematic name of this enzyme class is DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing DNA-adenine-forming). Other names in common use include DNA-4,6-diamino-5-formamidopyrimidine 8-''C'',9-''N''-lyase (cyclizing), DNA-4,6-diamino-5-formamidopyrimidine 8-''C'',9-''N''-lyase (cyclizing, DNA-adenine-forming).


References

* EC 4.3.2 Enzymes of unknown structure {{enzyme-stub