The purD RNA motif is a conserved

RNA Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid ( DNA) are nucleic acids. Along with lipids, proteins, and carbohydra ...

structure found in Campylobacterota, such as the genera '' Helicobacter'' and ''

Campylobacter ''Campylobacter'' (meaning "curved bacteria") is a genus of Gram-negative bacteria. ''Campylobacter'' typically appear comma- or s-shaped, and are motile. Some ''Campylobacter'' species can infect humans, sometimes causing campylobacteriosis, a d ...

''. The RNA is consistently found in the apparent

5' UTR The 5′ untranslated region (also known as 5′ UTR, leader sequence, transcript leader, or leader RNA) is the region of a messenger RNA (mRNA) that is directly upstream from the initiation codon. This region is important for the regulation of ...

of ''purD'' genes. ''purD'' genes encode the enzyme Phosphoribosylamine-glycine ligase, which catalyzes an early step in de novo purine synthesis. Although a possible ''cis''-regulatory role was proposed for this motif, experimental results indicate that it overlaps the 6S RNA of the relevant species, and that the second hairpin of the motif might not be biological.

References

External links

* Cis-regulatory RNA elements {{molecular-cell-biology-stub