In
enzymology
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
, a pterocarpin synthase () is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that
catalyzes
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:medicarpin + NADP
+ + H
2O
vestitone + NADPH + H
+
The 3
substrates of this enzyme are
medicarpin
Medicarpin is a pterocarpan, a derivative of isoflavonoids.
Natural occurrences
Medicarpin is found in ''Medicago truncatula'' and ''Swartzia madagascariensis''. It can also be found in ''Maackia amurensis'' cell cultures.
The root nodule form ...
,
NADP+, and
H2O, whereas its 3
products
Product may refer to:
Business
* Product (business), an item that serves as a solution to a specific consumer problem.
* Product (project management), a deliverable or set of deliverables that contribute to a business solution
Mathematics
* Produ ...
are
vestitone,
NADPH
Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NAD ...
, and
H+.
This enzyme belongs to the family of
oxidoreductase
In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule, the reductant, also called the electron donor, to another, the oxidant, also called the electron acceptor. This group of enzymes usually ut ...
s, specifically those acting on the CH-OH group of donor with NAD
+ or NADP
+ as acceptor. The
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
of this enzyme class is medicarpin:NADP
+ 2'-oxidoreductase. This enzyme is also called pterocarpan synthase. This enzyme participates in
isoflavonoid biosynthesis The biosynthesis of isoflavonoids involves several enzymes; These are:
Liquiritigenin,NADPH:oxygen oxidoreductase (hydroxylating, aryl migration), also known as Isoflavonoid synthase, is an enzyme that uses liquiritigenin (a flavanone), O2, NADPH ...
.
References
*
EC 1.1.1
NADPH-dependent enzymes
Enzymes of unknown structure
Isoflavonoids metabolism
{{1.1.1-enzyme-stub