Ψ-DOM, or 2,6-dimethoxy-4-methylamphetamine, is a

hallucinogenic Hallucinogens are a large, diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes. Most hallucinogens can be categorized ...

, psychedelic drug and a structural isomer of the better-known hallucinogen DOM. Ψ-DOM was first reported by Alexander Shulgin in his book '' PiHKAL''.Ψ-DOM Entry in PiHKAL
/ref> Ψ-DOM has similar effects to DOM, but is only around one third to one half the potency, with an active dose reported to be between 15-25 milligrams. The effects of Ψ-DOM last for around six to eight hours. The activity of Ψ-DOM (and Ψ-

2C-T-4 2C-T-4 (2,5-dimethoxy-4-isopropylthiophenethylamine) is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and is used as entheogenic recreational drug. Chemistry 2C-T-4 is the 2-carbon homolog of ...

) demonstrates that the two methoxy groups on the psychedelic phenethylamines are not strictly limited to the 2,5-positions on the phenyl ring. Indeed, any of the 2Cx or DOx series of drugs could alternatively be made as the 2,6-isomer and would still be expected to show similar activity, although slightly less potent. In theory this would vastly expand the range of different hallucinogens that could be derived from this family of drugs. The 2,6-isomer of another similar drug 2C-D-FLY (see

2C-B-FLY 2C-B-FLY is a psychedelic phenethylamine and designer drug of the 2C family. It was first synthesized in 1996 by Aaron P. Monte. Chemistry 2C-B-FLY is 8-bromo-2,3,6,7-benzo-dihydro-difuran-ethylamine. The full name of the chemical is 2-(8-bromo ...

) has also been made by David E. Nichols and found to be active, this might by extension be referred to as Ψ-2C-D-FLY.

References

{{Hallucinogenic phenethylamines Substituted amphetamines