The ''Pseudomonas'' rpsL leader is a putative attenuator

RNA Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid ( DNA) are nucleic acids. Along with lipids, proteins, and carbohydra ...

element identified by

bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...

searches within bacteria of the

Pseudomonadaceae The Pseudomonadaceae are a family of bacteria which includes the genera ''Azomonas'', ''Azorhizophilus'', ''Azotobacter'', '' Mesophilobacter'', ''Pseudomonas'' (the type genus), and '' Rugamonas''. The family Azotobacteraceae was recently recl ...

phylum. It is located upstream of the operon encoding

ribosomal protein A ribosomal protein (r-protein or rProtein) is any of the proteins that, in conjunction with rRNA, make up the ribosomal subunits involved in the cellular process of translation. ''E. coli'', other bacteria and Archaea have a 30S small subunit an ...

s S12 and S7 (''rpsL'' and ''rpsG'' genes respectively), and presents a Rho-independent terminator at the 3' end. This RNA is presumed to operate as a non-coding ribosomal protein leader potentially interacting with the S12 or S7 proteins, which are encoded by the

operon In genetics, an operon is a functioning unit of DNA containing a cluster of genes under the control of a single promoter. The genes are transcribed together into an mRNA strand and either translated together in the cytoplasm, or undergo splic ...

. The motif might be related to other rpsL leaders, such as the Rickettsia rpsL leader.

References

External links

* {{Rfam, id=RF01773, name=Pseudomonas rpsL leader Cis-regulatory RNA elements