Proxibarbital (Ipronal) is a

barbiturate Barbiturates are a class of depressant drugs that are chemically derived from barbituric acid. They are effective when used medically as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential as we ...

derivative synthesized in 1956. It has anti-anxiety properties and is, in contrast to most barbiturates, almost without hypnotic action. It was also used in the treatment of

migraine Migraine (, ) is a common neurological disorder characterized by recurrent headaches. Typically, the associated headache affects one side of the head, is pulsating in nature, may be moderate to severe in intensity, and could last from a few hou ...

headaches in a similar manner to butalbital.

Valofane Valofane is a sedative drug structurally related to the barbiturates and similar drugs such as primidone Primidone, sold under various brand names, is a barbiturate medication that is used to treat partial and generalized seizures, as well ...

isomerises to Proxibarbal in vivo.

References

Barbiturates Antimigraine drugs Allyl compounds {{sedative-stub