Proscillaridin is a

cardiac glycoside Cardiac glycosides are a class of organic compounds that increase the output force of the heart and decrease its rate of contractions by inhibiting the cellular sodium-potassium ATPase pump. Their beneficial medical uses are as treatments for co ...

, a kind of drug that can be used in the treatment of

congestive heart failure Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome, a group of signs and symptoms caused by an impairment of the heart's blood pumping function. Symptoms typically include shortness of breath, excessive fatigue, a ...

and

cardiac arrhythmia Arrhythmias, also known as cardiac arrhythmias, heart arrhythmias, or dysrhythmias, are irregularities in the heartbeat, including when it is too fast or too slow. A resting heart rate that is too fast – above 100 beats per minute in adults ...

(irregular heartbeat). It is of the

bufanolide Bufanolide is a C24 steroid and, indirectly, a parent structure of bufadienolide. Its derivatives was found in ''Bufo'' and ''Scilla'', as an aglycone of cardiac glycosides and is usually toxic Toxicity is the degree to which a chemical su ...

type and can be obtained from plants of the genus ''

Scilla ''Scilla'' () is a genus of about 30 to 80 species of bulb-forming perennial herbaceous plants in the family Asparagaceae, subfamily Scilloideae. Sometimes called the squills in English, they are native to woodlands, subalpine meadows, and sea ...

'' and in ''

Drimia maritima ''Drimia maritima'' ( syn. ''Urginea maritima'') is a species of flowering plant in the family Asparagaceae, subfamily Scilloideae (formerly the family Hyacinthaceae). This species is known by several common names, including squill, sea squill, s ...

'' (''Scilla maritima''). The

aglycone An aglycone (aglycon or genin) is the compound remaining after the glycosyl group on a glycoside is replaced by a hydrogen atom. For example, the aglycone of a cardiac glycoside would be a steroid molecule. Detection A way to identify aglycone ...

of proscillaridin is scillarenin.

References

Rhamnosides Bufanolides {{cardiovascular-drug-stub