Propionyl Chloride
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Propionyl chloride (also propanoyl chloride) is the
organic compound In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. T ...
with the formula CH3CH2C(O)Cl. It is the acyl chloride derivative of propionic acid. It undergoes the characteristic reactions of acyl chlorides. It is a colorless, corrosive, volatile liquid. It is used as a reagent for organic synthesis. In derived chiral amides and esters, the methylene protons are diastereotopic.


Synthesis

Propionyl chloride is industrially produced by chlorination of propionic acid with phosgene: :CH3CH2CO2H + COCl2 → CH3CH2COCl + HCl + CO2


References

{{reflist, 30em Acyl chlorides Reagents for organic chemistry