Procyanidin B2 is a
B type proanthocyanidin. Its structure is (−)-
Epicatechin
Catechin is a flavan-3-ol, a type of secondary metabolite providing antioxidant roles in plants. It belongs to the subgroup of polyphenols called flavonoids.
The name of the catechin chemical family derives from ''catechu'', which is the tanni ...
-(4β→8)-(−)-epicatechin.
Procyanidin B2 can be found in ''
Cinchona pubescens'' (Chinchona: in the rind, bark, and cortex), in ''
Cinnamomum verum
''Cinnamomum verum'', called true cinnamon tree or Ceylon cinnamon tree, is a small evergreen tree belonging to the family Lauraceae, native to Sri Lanka. The inner bark of several other '' Cinnamomum'' species are also used to make cinnamon, but ...
'' (Ceylon cinnamon: in the rind, bark, and cortex), in ''
Crataegus monogyna
''Crataegus monogyna'', known as common hawthorn, one-seed hawthorn, or single-seeded hawthorn, is a species of flowering plant in the rose family Rosaceae. It is native to Europe, northwestern Africa, and West Asia, but has been introduced in ...
'' (Common hawthorn: in the flower and blossom), in ''
Uncaria guianensis
''Uncaria guianensis'', the cat's claw, is a plant species in the genus ''Uncaria'' found in the Amazon biome. Other names for the plant include ''uña de gato'', ''Paraguayo'' and ''vincaria''.
''Uncaria guianensis'' contains many phytochemica ...
'' (Cat's claw: in the root), in ''
Vitis vinifera
''Vitis vinifera'', the common grape vine, is a species of flowering plant, native to the Mediterranean region, Central Europe, and southwestern Asia, from Morocco and Portugal north to southern Germany and east to northern Iran. There are curr ...
'' (Common grape vine: in the leaf), in ''
Litchi chinensis
Lychee (US: ; UK: ; ''Litchi chinensis''; ) is a monotypic taxon and the sole member in the genus ''Litchi'' in the soapberry family, ''Sapindaceae''.
It is a tropical tree native to Southeast and Southwest China (the Guangdong, Fujian, Yun ...
'' (litchi: in the pericarp),
[Immunomodulatory and anticancer activities of flavonoids extracted from litchi (Litchi chinensis Sonn.) pericarp. Mouming Zhao; Bao Yang; Jinshui Wang; Yang Liu; Limei Yu; Yueming Jiang, 2007](_blank)
/ref> in the apple
An apple is an edible fruit produced by an apple tree (''Malus domestica''). Apple trees are cultivated worldwide and are the most widely grown species in the genus ''Malus''. The tree originated in Central Asia, where its wild ancestor, ' ...
, and in '' Ecdysanthera utilis''.
Procyanidin B2 can be converted into procyanidin A2 by radical oxidation using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals under neutral conditions.
Procyanidin B2 has been shown to inhibit the formation of the advanced glycation end-product
Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars. They are a bio-marker implicated in aging and the development, or worsening, of many degenerative diseases, such as diabetes, ath ...
s pentosidine, carboxymethyllysine (CML), and methylglyoxal
Methylglyoxal (MGO) is the organic compound with the formula CH3C(O)CHO. It is a reduced derivative of pyruvic acid. It is a reactive compound that is implicated in the biology of diabetes. Methylglyoxal is produced industrially by degradation ...
(MGO).
See also
* Phenolic content in wine
The phenolic content in wine refers to the phenolic compounds—natural phenol and polyphenols—in wine, which include a large group of several hundred chemical compounds that affect the taste, color and mouthfeel of wine. These compounds include ...
References
Procyanidin dimers
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